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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies

Authors: Ester Blanco, Noelia Silva-Pilipich, Ana Bocanegra, Luisa Chocarro, Antonio Procopio, Karina Ausín, Joaquín Fernandez-Irigoyen, Leticia Fernández, Nerea Razquin, Ana Igea, Maider Garnica, Miriam Echaide, Hugo Arasanz, Ruth Vera, David Escors, Cristian Smerdou, Grazyna Kochan

Journal: Br J Cancer

PubMed ID: 38195888

Doi: 10.1038/s41416-023-02561-y

Products & Services: Molecular Biology Reagents

Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines

Authors: Roizza Beth So, Gang Li, Victoria Brentville, Janet M Daly, James E Dixon

Journal: J Control Release

PubMed ID: 38244841

Doi: 10.1016/j.jconrel.2024.01.031

Products & Services: ELISA Kits

Studying the topology of peroxisomal acyl-CoA synthetases using self-assembling split sfGFP

Authors: Serhii Chornyi, Janet Koster, Lodewijk IJlst, Hans R Waterham

Journal: Histochem Cell Biol

PubMed ID: 38243092

Doi: 10.1007/s00418-023-02257-7

Products & Services: Molecular Biology Reagents

Minimalist Nanovaccine with Optimized Amphiphilic Copolymers for Cancer Immunotherapy

Authors: Le Niu , Yu Miao , Zhiqin Cao , Ting Wei , Jiafei Zhu , Maoyi Li , Boxiong Bai , Linfu Chen , Nanhui Liu , Feng Pan , Junjie Zhu , Cheng Wang , Yang Yang , Qian Chen

Journal: ACS Nano .

PubMed ID: 38230639

Doi: 10.1021/acsnano.3c10174

Products & Services: Peptide Synthesis

Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide

Authors: Tian Xie , Feitong Dong , Gongshe Han , Xinyue Wu , Peng Liu , Zike Zhang , Jianlong Zhong , Somashekarappa Niranjanakumari , Kenneth Gable , Sita D Gupta , Wenchen Liu , Peter J Harrison , Dominic J Campopiano , Teresa M Dunn , Xin Gong

Journal: Cell Rep .

PubMed ID: 38285738

Doi: 10.1016/j.celrep.2024.113717

Products & Services: Protein and Antibody Isolation

Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit

Authors: Fuwen Zan, Yao Zhou, Ting Chen , Yahan Chen, Zhixia Mu, Zhaohui Qian , Xiuyuan Ou

Journal: Viruses.

PubMed ID: 38399999

Doi: 10.3390/v16020223

Products & Services: Gene Synthesis

Supramolecular Hydrogel with Ultra-Rapid Cell-Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration

Authors: Zhuo Li, Boguang Yang, Zhengmeng Yang, Xian Xie, Zhengnan Guo, Jianyang Zhao, Ruinan Wang, Hao Fu, Pengchao Zhao, Xin Zhao, Guosong Chen, Gang Li, Fuxin Wei, Liming Bian

Journal: Adv Mater .

PubMed ID: 38295393

Doi: 10.1002/adma.202307176

Products & Services: Peptide Synthesis

TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing

Authors: Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska

Journal: Brain

PubMed ID: 38226698

Doi: 10.1093/brain/awae014

Products & Services: Gene Synthesis Mutagenesis Services Plasmid DNA Preparation

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

Authors: Thomas E Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J Mentzer, Kathryn S Lilley, C Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E D Thaventhiran, Anne E Willis

Journal: Nature

PubMed ID: 38057663

Doi: 10.1038/s41586-023-06800-3

Products & Services: PCR Cloning and Subcloning Gene Synthesis

Predicting multiple conformations via sequence clustering and AlphaFold2

Authors: Hannah K Wayment-Steele, Adedolapo Ojoawo, Renee Otten, Julia M Apitz, Warintra Pitsawong, Marc Hömberger, Sergey Ovchinnikov, Lucy Colwell, Dorothee Kern

Journal: Nature

PubMed ID: 37956700

Doi: 10.1038/s41586-023-06832-9

Products & Services: Custom Vector Construction