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Augmenting macropinocytosis enhances the apoptotic body-mediated tumor deep penetration of nanomedicines

Authors: Bin Wan, Qiu Wang, Xiwei Jiang, Xianlu Zhang, Xiaoyuan Fan, Fengxiang Liu, Shipeng Ning, Meiling Zhang, Dongyan Liang, Lianwen Qi, Zhonggui He, Yinglei Zhai, Kaiyuan Wang, Jin Sun, Wei Tang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.112285

Products & Services: Peptide Synthesis

A GM-CSF-Flt3L Fused Adjuvant Enhances Immune Responses and Protective Efficacy of Influenza DNA Vaccine in Mice

Authors: Hongzhe Lin, Mingyue Chen, Rong Xiang, Yating Kang, Yiwei Zhong, Duan Ma, Bin Wang

Journal: Vaccines

Doi: 10.3390/vaccines14080671

Products & Services: Gene Fragments

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol-Mediated Cellular Uptake for miRNA Nano-Drugs

Authors: Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan

Journal: Advanced science

PubMed ID: 42658549

Doi: 10.1002/advs.77389

Products & Services: Peptide Synthesis

Reprogramming RNA Degraders as Intracellular Molecule Sensors for Tumor Cell Sensing and Manipulation

Authors: Pin-Ru Chen, Ying Han, Pei-Pei Qin, Ying-Yue Xu, Qian Tao, Bang-Ce Ye, Bin-Cheng Yin

Journal: ACS Sensors

PubMed ID: 42681980

Doi: 10.1021/acssensors.6c01983

Products & Services: Gene Synthesis

Nociceptive sensory nerves induce an IL4Rαhi anti-inflammatory macrophage subset that protects against kidney ischemia-reperfusion injury

Authors: Shun Zhang, Xiuwu Pan, Hailong Liu, Kaikai Chen, Shenggen Yu, Yu Shen, Jing Li, Ding Xu, Wang Zhou, Haibo Shen, Ying Wang, Xingang Cui

Journal: Kidney International

PubMed ID: 42176775

Doi: 10.1016/j.kint.2026.04.022

Products & Services: Recombinant Proteins

Caveola and Its Resident Proteins, Caveolin-1 and -2, Play Critical Roles in the Pathogenesis of nAMD and PCV

Authors: Richard Ming Chuan Yu, Gokce Oguz, Nai Yang Fu, Waseem Ahamed Shihabuddeen, Christine Cheung, Xiaomeng Wang, Tien Yin Wong, Chui Ming Gemmy Cheung, Adaikalavan Ramasamy, Yasuo Yanagi

Journal: investigative ophthalmology & visual science

PubMed ID: 42549844

Doi: 10.1167/iovs.67.10.10

Products & Services: Catalog IVT RNA products

siRNA-mediated mismatch repair disruption synergizes with oxaliplatin to restore immune surveillance in microsatellite-stable colorectal cancer

Authors: Jing Ni, Guantao He, Hongwei Wang, Yao Qin, Jianping Guo, Yuhang Wang, Keqian Du, Di Zhang, Yanxin Luo, Jiang Xia, Yingjie Li, Lin-Ping Wu

Journal: Molecular cancer

Doi: doi.org/10.1186/s12943-026-02752-0

Products & Services: Custom mRNA synthesis

A non-classical biosynthetic route enables tocopherol synthesis in bacteria

Authors: Yang Zhang, Zhizhen Li, Lichuang Cao, Yan Wang, Junyi Wang, Haofeng Chen, Wenhao Li, Xinyu Gao, Qingchen Li, Zhengxin Chen, Kaixuan Xu, Xiangpeng Yang, Xiangrui Wu, Jintao Luo, Jianzhong Liu, Jifeng Yuan

Journal: nature metabolism

PubMed ID: 42509462

Doi: 10.1038/s42255-026-01576-y

Products & Services: Codon Optimization

Neurabin I haploinsufficiency disrupts ion channel regulation and synaptic maturation in human cortical neurons in neurodevelopmental disorders

Authors: Binte Zehra, Nesrin Mohamed, Richa Tambi, Muhammad Faizan, Dharana Satsangi, Alexander D Giddey, Gilles Bru-Mercier, Ahmad Farhat, Nesreen K Al-Jezawi, Muhammad Kumail, Nasna Nassir, Bipin Balan, Noor Kosaji, Mariam Eldesouky, Talal Al Yazeedi, Shuhd BinEshaq, Suhana Shiyas, Nidhina Vinod, Saif S Alqassim, Awab Ahmed, Mohammad Amiruddin Hashmi, Nelson C Soares, Marc Woodbury-Smith, Stefan S Du Plessis, Dimitri J Stavropoulos, Stephen W Scherer, Alawi Alsheikh-Ali, Reem Khalil, Mauro Pessia, Maria Cristina D'Adamo, Bakhrom K Berdiev, Mohammed Uddin

Journal: Molecular Psychiatry

PubMed ID: 42603820

Doi: 10.1038/s41380-026-03818-7

Products & Services: PCR Cloning and Subcloning

RNA synthesis and substrate analog inhibition in the CCHFV polymerase

Authors: Hengxia Jia, Bo Tang, Shunli Liu, Xin Wen, Fan Wu, Xiao Hu, Hu Zhou, Tingting Chong, Lincan Lv, Qiaojie Liu, Guibo Rao, Mingyu Wei, Xuping Jing, Sheng Cao, Fei Deng, Zhihong Hu, Bo Shu, Rui Gong, Jiqin Wu, Manli Wang, Peng Gong

Journal: Nature

Doi: 10.1038/s41586-026-10913-w

Products & Services: PCR Cloning and Subcloning