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IgG hexamers initiate complement-dependent acute lung injury

Authors: Simon J Cleary, Yurim Seo, Jennifer J Tian, Nicholas Kwaan, David P Bulkley, Arthur Eh Bentlage, Gestur Vidarsson, Éric Boilard, Rolf Spirig, James C Zimring, Mark R Looney

Journal: J Clin Invest

PubMed ID: 38530369

Doi: 10.1172/JCI178351

Products & Services: Protein and Antibody Isolation

The replication phenotype of hepatitis B virus (HBV) splice variants Sp3 and Sp9 and their impact on wild-type HBV replication

Authors: Laura C McCoullough, Tomas Sadauskas, Vitina Sozzi, Kai Yan Mak, Hugh Mason, Margaret Littlejohn, Peter A Revill

Journal: J Virol

PubMed ID: 38501924

Doi: 10.1128/jvi.01538-23

Products & Services: Protein and Antibody Isolation

A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results

Authors: Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson, Brian S Henick, Chih-Yi Liao, Amit Mahipal, Ardaman Shergill, Alexander I Spira, Jonathan W Goldman, Ciaran D Scallan, Desiree Schenk, Christine D Palmer, Matthew J Davis, Sonia Kounlavouth, Lindsey Kemp, Aaron Yang, Yaojun John Li, Molly Likes, Annie Shen, Gregory R Boucher, Milana Egorova, Robert L Veres, J Aaron Espinosa, Jason R Jaroslavsky, Lauren D Kraemer Tardif, Lindsey Acrebuche, Christopher Puccia, Leiliane Sousa, Rita Zhou, Kyounghwa Bae, J Randolph Hecht, David P Carbone, Benny Johnson, Andrew Allen, Andrew R Ferguson, Karin Jooss

Journal: Nat Med

PubMed ID: 38538867

Doi: 10.1038/s41591-024-02851-9

Products & Services: Molecular Biology Reagents

Long-term effects of Omicron BA2 breakthrough infection on immunity-metabolism balance: a 6-month prospective study

Authors: Yanhua Li, Shijie Qin, Lei Dong, Shitong Qiao, Xiao Wang, Dongshan Yu, Pengyue Gao, Yali Hou, Shouzhen Quan, Ying Li, Fengyan Fan, Xin Zhao, Yueyun Ma, George Fu Gao

Journal: Nat Commun

PubMed ID: 38503738

Doi: 10.1038/s41467-024-46692-z

Products & Services: Molecular Biology Reagents

Identification of mA RNA methylation genes in and expression profiling in response to different developmental and environmental stimuli

Authors: Mahbub Hasan, Zakia Sultana Nishat, Md Soyib Hasan, Tanvir Hossain, Ajit Ghosh

Journal: Biochem Biophys Rep

PubMed ID: 38511186

Doi: 10.1016/j.bbrep.2024.101677

Products & Services: Protein and Antibody Isolation

CIRP increases Foxp3 regulatory T cells and inhibits development of Th17 cells by enhancing TLR4-IL-2 signaling in the late phase of sepsis

Authors: Zongsheng Wu, Xu Liu, Wei Huang, Jing Chen, Songli Li, Jie Chao, Jianfeng Xie, Ling Liu, Yi Yang, Xiaojing Wu, Haibo Qiu

Journal: Int Immunopharmacol

PubMed ID: 38531201

Doi: 10.1016/j.intimp.2024.111924

Products & Services: Recombinant Proteins

Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity

Authors: Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, Jarek Juraszek, Aneesh Vijayan, Sonja Schmit-Tillemans, Johan Verspuij, Ying Choi, Chenandly E Daal, Aditya Perkasa, Shessy Torres Morales, Sebenzile K Myeni, Marjolein Kikkert, Jeroen Tolboom, Daniëlle van Manen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Johannes P M Langedijk

Journal: Sci Rep

PubMed ID: 38459086

Doi: 10.1038/s41598-024-56293-x

Products & Services: Codon Optimization

Atrogin-1 promotes muscle homeostasis by regulating levels of endoplasmic reticulum chaperone BiP

Authors: Avnika A Ruparelia, Margo Montandon, Jo Merriner, Cheng Huang, Siew Fen Lisa Wong, Carmen Sonntag, Justin P Hardee, Gordon S Lynch, Lee B Miles, Ashley Siegel, Thomas E Hall, Ralf B Schittenhelm, Peter D Currie

Journal: JCI Insight

PubMed ID: 38530354

Doi: 10.1172/jci.insight.167578

Products & Services: Molecular Biology Reagents

Mucosal tumor vaccination delivering endogenous tumor antigens protects against pulmonary breast cancer metastases

Authors: Friederike Oltmanns, Ana Vieira Antão, Pascal Irrgang, Vera Viherlehto, Leticia Jörg, Anna Schmidt, Jannik T Wagner, Michael Rückert, Ann-Sophie Flohr, Carol Imanuel Geppert, Benjamin Frey, Wibke Bayer, Claudia Gravekamp, Matthias Tenbusch, Udo Gaipl, Dennis Lapuente

Journal: J Immunother Cancer

PubMed ID: 38458636

Doi: 10.1136/jitc-2023-008652

Products & Services: Peptide Synthesis

CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

Authors: Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Inaki Etxeberria, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A Klebanoff

Journal: biorxiv

PubMed ID: 38464085

Doi: 10.1101/2024.02.26.582108

Products & Services: Gene Synthesis