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页码: 102/5357 每页显示数量

RIG-I-Inducing Small Molecules Potently Inhibit HMA-Resistant AML Through Igniting the Overloaded dsRNA Arsenal

Authors: Xueqin Chen 1, Jiaqi Wu 1, Yuntong Li 1, Jiayu Huang 1, Xiangqin Weng 1, Jiale Wu 1, Shujun Xiao 1 2, Huaxin Song 1, Zhengyuan Wang 1, Ni Yan 1, Fangfang Shi 1, Derun Zheng 1 2, Kai Tan 1 2, Hesong Zhang 1, Jingyi Cui 1 2, Wen Wu 1, Wei Wu 3, Sujiang Zhang 1, Min Lu 1

Journal: Advanced Science

PubMed ID: 40568903

Doi: 10.1002/advs.202414477

Products & Services: Catalog Antibodies

Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis

Authors: Kewei Rong, Dezheng Wang, Xiting Pu, Cheng Zhang, Pu Zhang, Xiankun Cao, Jinglin Zheng, Xiao Yang, Kexin Liu, Lei Shi, Yin Li, Peixiang Ma, Dan Ye, Jie Zhao, Pu Wang, An Qin

Journal: Bone Research

PubMed ID: 40500265

Doi: 10.1038/s41413-025-00437-w

Products & Services: Protein and Antibody Isolation

Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish

Authors: Sema Elif Eski, Jiarui Mi, Macarena Pozo-Morales, Gabriel Garnik Hovhannisyan, Camille Perazzolo, Rita Manco, Imane Ez-Zammoury, Dev Barbhaya, Anne Lefort, Frédérick Libert, Federico Marini, Esteban N Gurzov, Olov Andersson, Sumeet Pal Singh

Journal: nature COMMUNICATION

PubMed ID: 40480975

Doi: 10.1038/s41467-025-60334-y

Products & Services: Gene Synthesis

Histidine-Specific Modification of Chitin-Binding protein21 via Visible Light-Mediated C–H Functionalization and Protein Ligation

Authors: Xinliang Liu, Ping Wang and Farong Ye

Journal: CCS Chemistry

Doi: 10.31635/ccschem.024.202404864

Products & Services: Gene Synthesis Plasmid DNA Preparation

High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1

Authors: Judith Reeks, Pravin Mahajan, Mellissa Clark, Suzanna R Cowan, Elena Di Daniel, Christopher P Earl, Samantha Fisher, Rhian S Holvey, Scott M Jackson, Emyr Lloyd-Evans, Carmine M Morgillo, Paul N Mortenson, Marc O'Reilly, Caroline J Richardson, Patrick Schöpf, Daniel M Tams, Helen Waller-Evans, Simon E Ward, Stuart Whibley, Pamela A Williams, Christopher N Johnson

Journal: Structure

PubMed ID: 40532704

Doi: 10.1016/j.str.2025.05.014

Products & Services: Codon Optimization

Host protein ARF1 is a proviral factor for SARS-CoV-2 and a candidate broad-spectrum therapeutic target

Authors: Cunhuan Zhang, Yuan-Qin Min, Heng Xue, Haiyan Zhang, Kunpeng Liu, Yichao Tian, Ziying Yang, Zihan Zhao, Hang Yang, Chao Shan, Xiulian Sun & Yun-Jia Ning

Journal: nature COMMUNICATION

Doi: 10.1038/s41467-025-61431-8

Products & Services: Peptide Synthesis

Patch-Clamp-like Micropipette Electrode with Exterior and Interior Interfaces for Simultaneous Monitoring of Extracellular and Intracellular Serotonin across Neuron

Authors: Jie Liu, Qin Zhou, Yuandong Liu,Yang Tian

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Doi: 10.1002/anie.202504408

Products & Services: Gene Synthesis

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Authors: Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A Hoffmann, Jichao Fang, Rui Ji

Journal: Advanced Science

PubMed ID: 40167256

Doi: 10.1002/advs.202415474

Products & Services: Peptide Synthesis

Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cells

Authors: Elisabetta Petrozziello, Amina Sayed, João A Freitas, Christine Federle, Jelena Nedjic, Sarina Ravens, Batuhan Akçabozan, Anna M Schulz, Dietmar Zehn, Marc Schmidt-Supprian, Reinhard Obst, Immo Prinz, Martijn Verdoes, Jan Kisielow, Thomas Reinheckel, Tobias Straub, Stephen R Daley, Ludger Klein

Journal: nature immunology

PubMed ID: 40514418

Doi: 10.1038/s41590-025-02182-y

Products & Services: Peptide Synthesis

Constitutive down-regulation of liguleless alleles in sorghum drives increased productivity and water use efficiency

Authors: Nikhil Jaikumar, Truyen Quach, Zhengxiang Ge, Natalya Nersesian, Shirley J Sato, Scott M McCoy, Ming Guo, Andrew D B Leakey, Stephen P Long, Tom Elmo Clemente

Journal: Plant Biotechnology Journal.

PubMed ID: 40452217

Doi: 10.1111/pbi.70150

Products & Services: Gene Synthesis