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页码: 101/5234 每页显示数量

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus

Authors: Min Lin, Yifan Yin, Xiaomeng Zhao, Chen Wang, Xueqing Zhu, Letao Zhan, Li Chen, Siling Wang, Xue Lin, Jun Zhang, Ningshao Xia, Zizheng Zheng

Journal: Nat Commun

PubMed ID: 39910047

Doi: 10.1038/s41467-025-56302-1

Products & Services: Protein and Antibody Isolation

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

Authors: Shahid Banday, Alok K Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T Yustein, Michelle A Kelliher, Lihua Julie Zhu, Sara K Deibler, Sunil K Malonia, Michael R Green

Journal: Nature Communications

PubMed ID: 39894896

Doi: 10.1038/s41467-025-56632-0

Products & Services: Plasmid DNA Preparation

Structural basis of SIRT7 nucleosome engagement and substrate specificity

Authors: Carlos Moreno-Yruela, Babatunde E Ekundayo, Polina N Foteva, Dongchun Ni, Esther Calvino-Sanles, Henning Stahlberg, Beat Fierz

Journal: Nature Communications

PubMed ID: 39900593

Doi: 10.1038/s41467-025-56529-y

Products & Services: Protein Electrophoresis and Western

Synthetic lethality of mRNA quality control complexes in cancer

Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik

Journal: Nature

PubMed ID: 39910291

Doi: 10.1038/s41586-024-08398-6

Products & Services: Custom Vector Construction

Antibody prophylaxis may mask subclinical SIV infections in macaques

Authors: Christopher A Gonelli, Hannah A D King, SungYoul Ko, Christine M Fennessey, Nami Iwamoto, Rosemarie D Mason, Ashley Heimann, Dillon R Flebbe, John-Paul Todd, Kathryn E Foulds, Brandon F Keele, Jeffrey D Lifson, Richard A Koup, Mario Roederer.

Journal: Nature

PubMed ID: 39910294

Doi: 10.1038/s41586-024-08500-y

Products & Services: Gene Synthesis

Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I

Authors: Bryan Neumann, Stephen McCarthy, Shane Gonen

Journal: Nature Communications

PubMed ID: 39920100

Doi: 10.1038/s41467-024-55764-z

Products & Services: Codon Optimization

Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism

Authors: Laleh Khodaparast, Ladan Khodaparast, Ramon Duran-Romaña, Guiqin Wu, Bert Houben, Wouter Duverger, Matthias De Vleeschouwer, Katerina Konstantoulea, Fleur Nysen, Thomas Schalck, Daniel J Curwen, Lisandra L Martin, Sebastien Carpentier, Bernard Scorneaux, Jan Michiels, Joost Schymkowitz, Frederic Rousseau

Journal: Nature Communications

PubMed ID: 39939597

Doi: 10.1038/s41467-025-56873-z

Products & Services: Peptide Synthesis

Cascaded immunotherapy with implantable dual-drug depots sequentially releasing STING agonists and apoptosis inducers

Authors: Kai Li, Xuan Yu, Yanteng Xu, Haixia Wang, Zheng Liu, Chong Wu, Xing Luo, Jiancheng Xu, Youqiang Fang, Enguo Ju, Shixian Lv, Hon Fai Chan, Yeh-Hsing Lao, Weiling He, Yu Tao, Mingqiang Li

Journal: Nature Communications

PubMed ID: 39952937

Doi: 10.1038/s41467-025-56407-7

Products & Services: Recombinant Proteins

Proteasomes accumulate in the plant apoplast where they participate in microbe-associated molecular pattern (MAMP)-triggered pathogen defense

Authors: Hana Zand Karimi, Kuo-En Chen, Marilee Karinshak, Xilin Gu, Jason K Sello, Richard D Vierstra

Journal: Nature Communications

PubMed ID: 39952938

Doi: 10.1038/s41467-025-56594-3

Products & Services: Peptide Synthesis