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Senescence-regulating agents remodel mesenchymal stem cell-schwann cell circuitry for diabetic bone regeneration

Authors: An Lao, Yiting Sun, Weiqi Li, Yu Zhuang, Ziyang Liu, Chenci Xu, Xiangbing Wu, Linhu Ge, Kaili Lin, Jianyong Wu, Jing Mao, Jiaqiang Liu

Journal: Biomaterials

PubMed ID: 40916241

Doi: 10.1016/j.biomaterials.2025.123656

Products & Services: Protein and Antibody Isolation

Optimised modular anti‐FLAG CAR T cells for solid tumor therapy

Authors: Xiaomeng Zhang, Rachel Xu, Dmitry Zorin, Evan G Pappas, Jiawei Tang, Yuchen Bai, Vicky M Qin, Bianca von Scheidt, Ruihong Huang, Weronika Kulakowska, Charbel Darido, Phillip K Darcy, Michael H Kershaw, Clare Y Slaney

Journal: Clinical & Translational Immunology

PubMed ID: 40851786

Doi: 10.1002/cti2.70046

Products & Services: Recombinant Proteins Gene Synthesis

A receptor antagonist counterbalances multiple systemin phytocytokines in tomato

Authors: Lei Wang, Louis-Philippe Maier, Nga Pham, Yan L Wang, Xu Wang, Andreas Schaller, Judith Fliegmann, Matthias Erb, Thomas Boller, Georg Felix

Journal: Cell

PubMed ID: 40845839

Doi: 10.1016/j.cell.2025.07.044

Products & Services: Peptide Synthesis

Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies

Authors: Julia Lederhofer, Andrew J Borst, Lam Nguyen, Rebecca A Gillespie, Connor J Williams, Emma L Walker, Julie E Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon-Xhi Tan, Thi H T Do, Michelle Ravichandran, Adrian B McDermott, Valerie Le Sage, Sarah F Andrews, Barney S Graham, Adam K Wheatley, Douglas S Reed, Neil P King, Masaru Kanekiyo

Journal: Nature Communications

PubMed ID: 40750617

Doi: 10.1038/s41467-025-62339-z.

Products & Services: Custom Vector Construction

Identification of distinct epitopes in dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid

Authors: Shoko Mai https://orcid.org/0000-0001-5468-6851, Yosuke Mai https://orcid.org/0000-0001-6356-7192, Inkin Ujiie https://orcid.org/0000-0002-7931-949X, Kentaro Izumi https://orcid.org/0000-0001-8221-9644, Ken Natsuga https://orcid.org/0000-0003-3865-6366, Wataru Nishie https://orcid.org/0000-0002-0486-9112, and Hideyuki Ujiie

Journal: SCIENCE ADVANCES

PubMed ID: 40749047

Doi: 10.1126/sciadv.adv9423

Products & Services: Custom Vector Construction

An Apple Susceptibility-Related LRR Receptor-Like Kinase MdRLKT21 Activates Plant Immunity by Hijacking a Trans-Kingdom Fungal microRNA-Like RNA

Authors: Mingliang Lei, Jian Zhang, Jie Wang, Chengyu Gao, Yanting He, Runze Tian, Hao Feng, Lili Huang

Journal: Advanced Science

PubMed ID: 40755370

Doi: 10.1002/advs.202417426

A rapid, simple, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies

Authors: Jessey Erath, Danielle Kemper, Elisha Mugo, Alex Jacoby, Elizabeth Valenzuela, Courtney F Jungers, Wandy L Beatty, Yaser Hashem, Marko Jovanovic, Sergej Djuranovic, Slavica Pavlovic Djuranovic

Journal: Nature Communications

PubMed ID: 40764614

Doi: 10.1038/s41467-025-62314-8.

Products & Services: CRISPR Cell Lines

14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state

Authors: Juliana A Martinez Fiesco, Alexandra Beilina, Astrid Alvarez de la Cruz, Ning Li, Riley D Metcalfe, Mark R Cookson, Ping Zhang

Journal: Nature Communications

PubMed ID: 40764514

Doi: 10.1038/s41467-025-62337-1.

Products & Services: Codon Optimization

Structural basis of fast N-type inactivation in Kv channels

Authors: Xiao-Feng Tan, Ana I Fernández-Mariño, Yan Li, Tsg-Hui Chang, Kenton J Swartz

Journal: Nature

PubMed ID: 40770100

Doi: 10.1038/s41586-025-09339-7

Products & Services: Peptide Synthesis

Lipid interactions and gating hysteresis suggest a physiological role for mechanosensitive channel YnaI

Authors: Nathan Will, Giorgos Hiotis, Yoshitaka Nakayama, Gabriella Angiulli, Zijing Zhou, Charles D Cox, Boris Martinac, Thomas Walz

Journal: Nature Communications

PubMed ID: 40796571

Doi: 10.1038/s41467-025-62805-8.

Products & Services: PCR Cloning and Subcloning