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The mitotic chromosome periphery modulates chromosome mechanics

Authors: Tania Mendonca, Roman Urban, Kellie Lucken, George Coney, Neil M Kad, Manlio Tassieri, Amanda J Wright, Daniel G Booth

Journal: Nature Communications

PubMed ID: 40640170

Doi: 10.1038/s41467-025-61755-5

Products & Services: Gene Synthesis

The defensome of prokaryotes in aquifers

Authors: Pengwei Li, Zongzhi Wu, Tang Liu, Chunfang Deng, Quan Liu, Jinren Ni

Journal: Nature Communications

PubMed ID: 40659683

Doi: 10.1038/s41467-025-61467-w

Products & Services: PCR Cloning and Subcloning

Structure-guided engineering of snake toxins for selective modulation of adrenergic and muscarinic receptors

Authors: Yixuan Zhong, Huihui Tao, Yu Zhang, Binbin He, Haizhan Jiao, Dandan Wang, Maikun Teng, Hongli Hu, Qiong Guo, Yuyong Tao

Journal: Nature Communications

PubMed ID: 40659608

Doi: 10.1038/s41467-025-61695-0

Scaffold-hopping for molecular glues targeting the 14-3-3/ERα complex

Authors: Markella Konstantinidou, Marios Zingiridis, Marloes A M Pennings, Michael Fragkiadakis, Johanna M Virta, Jezrael L Revalde, Emira J Visser, Christian Ottmann, Luc Brunsveld, Constantinos G Neochoritis, Michelle R Arkin

Journal: Nature Communications

PubMed ID: 40659654

Doi: 10.1038/s41467-025-61176-4

Products & Services: Peptide Synthesis

Higher resolution pooled genome-wide CRISPR knockout screening in Drosophila cells using integration and anti-CRISPR (IntAC)

Authors: Raghuvir Viswanatha, Samuel Entwisle, Yanhui Hu, Ah-Ram Kim, Kelly Reap, Matthew Butnaru, Mujeeb Qadiri, Stephanie E Mohr, Norbert Perrimon

Journal: Nature Communications

PubMed ID: 40659672

Doi: 10.1038/s41467-025-61692-3

Products & Services: Custom Vector Construction

Non-antibiotics disrupt colonization resistance against enteropathogens

Authors: Anne Grießhammer, Jacobo de la Cuesta-Zuluaga, Patrick Müller, Cordula Gekeler, Jan Homolak, Hsuan Chang, Katharina Schmitt, Chiara Planker, Verena Schmidtchen, Suchira Gallage, Erwin Bohn, Taylor H Nguyen, Jenny Hetzer, Mathias Heikenwälder, Kerwyn Casey Huang, Taiyeb Zahir, Lisa Maier

Journal: Nature

PubMed ID: 40670795

Doi: 10.1038/s41586-025-09217-2

Products & Services: Gene Synthesis

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Authors: Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S Yarla, Lu Wang, Jindan Yu, Jonathan C Zhao, Ivet Bahar, Yong Wan

Journal: Advanced Science

PubMed ID: 40671262

Doi: 10.1002/advs.202415585

Products & Services: Custom Vector Construction

Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

Authors: De Xing, Tao Bai, Ozlem Neyisci, Seyedeh Zahra Paylakhi, Alexander J Duval, Yasemin Tekin, Mazhar Adli

Journal: Nature Communications

PubMed ID: 40681502

Doi: 10.1038/s41467-025-61848-1

Products & Services: Gene Synthesis

Natural variation of an E3 ubiquitin ligase encoding gene Chalk9 regulates grain chalkiness in rice

Authors: Zhi Hu, Hongchun Liu, Min Guo, Xiang Han, Youguang Li, Rujia Chen, Yifan Guo, Yihao Yang, Shengyuan Sun, Yong Zhou, Minghong Gu, Changjie Yan

Journal: Nature Communications

PubMed ID: 40683885

Doi: 10.1038/s41467-025-61683-4

Products & Services: Polyclonal Antibody Services

Metabolic modulation-driven self-reinforcing pyroptosis-STING nanoadjuvant for potentiated metalloimmunotherapy

Authors: Linzhu Zhang, Di Wang, Yiming Liu, Nailin Yang, Shumin Sun, Chunjie Wang, Duo Wang, Jihu Nie, Juan Qin, Lei Zhang, Liang Cheng, Haidong Zhu

Journal: Bioactive Materials

PubMed ID: 40792115

Doi: 10.1016/j.bioactmat.2025.07.040

Products & Services: Protein and Antibody Isolation