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Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL main protease (Mpro) from proteomic identification of P6-P6' active site specificity

Authors: Hugo Cesar Ramos de Jesus, Nestor Solis, Yoan Machado, Isabel Pablos, Peter A Bell, Reinhild Kappelhoff, Peter M Grin, Carlos A Sorgi, Georgina S Butler, Christopher M Overall

Journal: J Virol

PubMed ID: 38742901

Doi: 10.1128/jvi.00049-24

Products & Services: Peptide Synthesis

A vector system for single and tandem expression of cloned genes and multi-colour fluorescent tagging in

Authors: Solenne Ithurbide, Roshali T de Silva, Hannah J Brown, Vinaya Shinde, Iain G Duggin

Journal: Microbiology (Reading)

PubMed ID: 38787390

Doi: 10.1099/mic.0.001461

Products & Services: Protein and Antibody Isolation

Poc1 bridges basal body inner junctions to promote triplet microtubule integrity and connections

Authors: Marisa D Ruehle, Sam Li, David A Agard, Chad G Pearson

Journal: J Cell Biol

PubMed ID: 38743010

Doi: 10.1083/jcb.202311104

Products & Services: Molecular Biology Reagents

A converged ubiquitin‐proteasome pathway for the degradation of TOC and TOM tail‐anchored receptors

Authors: Meijing Yang , Shuai Chen , Shey-Li Lim , Lang Yang , Jia Yi Zhong , Koon Chuen Chan , Zhizhu Zhao , Kam-Bo Wong , Junqi Wang , Boon Leong Lim

Journal: Journal of integrative plant biology

PubMed ID: 38501483

Doi: doi.org/10.1111/jipb.13645

Products & Services: Catalog Antibodies

Amplifiable protein identification via residue-resolved barcoding and composition code counting

Authors: Weiming Guo , Yuan Liu , Yu Han , Huan Tang , Xinyuan Fan , Chu Wang , Peng R Chen

Journal: National Science Review

PubMed ID: 39055168

Doi: 10.1093/nsr/nwae183

Products & Services: Peptide Synthesis

Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes

Authors: Anna Ściuk, Kinga Wątor, Izabela Staroń, Paulina Worsztynowicz, Kinga Pokrywka, Joanna Sliwiak, Marta Kilichowska, Kamila Pietruszewska, Zofia Mazurek, Anna Skalniak, Krzysztof Lewandowski, Mariusz Jaskolski, Joanna I Loch, Marcin Surmiak

Journal: Molecules

PubMed ID: 38792133

Doi: 10.3390/molecules29102272

Products & Services: Gene Synthesis

Biophysical insights into the dimer formation of human Sirtuin 2

Authors: Noa Suzuki, Tsuyoshi Konuma, Takahisa Ikegami, Satoko Akashi

Journal: Protein Sci

PubMed ID: 38647411

Doi: 10.1002/pro.4994

Products & Services: Catalog Peptides

Identification and characterisation of novel CAR-T cells to target IL13Rα2 positive human glioma in vitro and in vivo

Authors: Pamela Leland, Heba Degheidy, Ashley Lea, Steven R Bauer, Raj K Puri, Bharat H Joshi

Journal: Clin Transl Med

PubMed ID: 38685487

Doi: 10.1002/ctm2.1664

Products & Services: Codon Optimization

Construction and in vitro characterisation of virus-vectored immunocontraceptive candidates derived from felid alphaherpesvirus 1

Authors: Ellen Cottingham, Thurid Johnstone, Paola K Vaz, Carol A Hartley, Joanne M Devlin

Journal: Vaccine

PubMed ID: 38824082

Doi: 10.1016/j.vaccine.2024.05.047

Products & Services: Custom Vector Construction

A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2

Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H Yennawar, Squire J Booker, Kirill A Afonin, Nikolay V Dokholyan

Journal: ACS Appl Bio Mater

PubMed ID: 38700999

Doi: 10.1021/acsabm.4c00222

Products & Services: Protein and Antibody Isolation