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A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity

Authors: Fernanda Ana-Sosa-Batiz; Shailendra Kumar Verma; Norazizah Shafee; Robyn Miller; Chris Conner; Kathryn M. Hastie; Julia Timis; Erin Maule; Michael N. Nguyen; Linda Tran; Krithik Varghese; Henry Madany; Audrey Elizabeth Street; Michelle Zandonatti; Meng Ling Moi; Kurt Jarnagin; David R. Webb; Erica Ollmann Saphire; Kenneth Kim; Sujan Shresta

Journal: EBioMedicine

PubMed ID: 40020261

Doi: 10.1016/j.ebiom.2025.105619

Products & Services: Protein and Antibody Isolation

Astragalus Polysaccharides Ameliorate Diabetic Bladder Dysfunction via Normalization of Neuromuscular Conduction

Authors: Shaochan Liang, Siyuan Xu, Shenglian Ye, Lang Liang, Hongliang Li, Jiaye Liu, Yao Zhang, Feng Zou, Xiaodan Liang, Bo Tan, Hongying Cao

Journal: J Agric Food Chem

PubMed ID: 40032633

Doi: 10.1021/acs.jafc.4c11577

Products & Services: Protein and Antibody Isolation

The structure and function of the ghrelin receptor coding for drug actions

Authors: Yuki Shiimura, Dohyun Im, Ryosuke Tany, Hidetsugu Asada, Ryoji Kise, Eon Kurumiya, Hideko Wakasugi-Masuho, Satoshi Yasuda, Kazuma Matsui, Jun-Ichi Kishikawa, Takayuki Kato, Takeshi Murata, Masayasu Kojima, So Iwata, Ikuo Masuho

Journal: Nat Struct Mol Biol

PubMed ID: 39833471

Doi: 39833471

Products & Services: Gene Synthesis

Expediting Genome Synthesis of Corynebacterium glutamicum with An Artificial Chromosome Vector

Authors: Zhanhua Zhang, Peixiong Hong, Zebin Li, Baitao Li, Tai Chen, Yue Shen, Xiaofeng Yang, Yanrui Ye, Yun Wang, Zhanglin Lin

Journal: Trends Biotechnol

PubMed ID: 40155267

Doi: 10.1016/j.tibtech.2025.02.019

Products & Services: Protein and Antibody Isolation

The E3 ubiquitin ligase SlATL2 suppresses tomato immunity by promoting SlCSN5a degradation during Pseudomonas syringae pv. tomato DC3000 infection

Authors: Yujie Dai, Xiaodan Li, Yeling He, Liya Zhu, Yan Bi, Fengming Song, Dayong Li

Journal: Horticulture research

PubMed ID: 40303438

Doi: 10.1093/hr/uhaf078

Products & Services: Protein and Antibody Isolation

The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Authors: Yijian Qiu; Olivia T. Stamatatos; Qingting Hu; Jed de Ruiter Swain; Suzanne Russo; Ava Sann; Ana S. H. Costa; Sara Violante; David L. Spector; Justin R. Cross; Michael J. Lukey

Journal: Nature metabolism

PubMed ID: 39192144

Doi: 10.1038/s42255-024-01104-w

Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Authors: Junquan Song, Rongyuan Wei, Chenchen Liu, Zhenxiong Zhao, Xuanjun Liu, Yanong Wang, Fenglin Liu, Xiaowen Liu

Journal: Nature Communications

PubMed ID: 40038297

Doi: 10.1038/s41467-025-57465-7

Products & Services: Peptide Services

Structural basis for the activation of plant bunyavirus replication machinery and its dual-targeted inhibition by ribavirin

Authors: Jia Li, Lei Cao, Yaqian Zhao, Jinghan Shen, Lei Wang, Mingfeng Feng, Min Zhu, Yonghao Ye, Richard Kormelink, Xiaorong Tao, Xiangxi Wang

Journal: Nat Plants

PubMed ID: 40044941

Doi: 10.1038/s41477-025-01940-y

Oxytocin induces embryonic diapause

Authors: Jessica L Minder, Sarah B Winokur, Janaye Stephens, Jie Tong, Naomi L Cassel, Luisa Schuster, Habon A Issa, Michael Cammer, Latika Khatri, Gaia Moisan, Maria Alvarado-Torres, Orlando Aristizábal, Youssef Z Wadghiri, Sang Yong Kim, Silvana Valtcheva, Catherine Pei-Ju Lu, Moses V Chao, Robert C Froemke

Journal: SCIENCE ADVANCES

PubMed ID: 40043121

Doi: 10.1126/sciadv.adt1763

Products & Services: Peptide Synthesis

Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Authors: Gabrielle S Blizard, Garima Dwivedi, Yi-Gen Pan, Catherine Hou, Jean M Etersque, Hooda Said, Anik Chevrier, Marc Lavertu, Houping Ni, Benjamin Davis, Ying Tam, Quy Cao, Robert H Mach, Drew Weissman, Mohamad-Gabriel Alameh, Mark A Sellmyer

Journal: Nature Communications

PubMed ID: 40044669

Doi: 10.1038/s41467-025-57446-w

Products & Services: Endotoxin Detection & Removal System