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Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

Authors: Chen Xiang; Kaja Arusha; Danielle Springer; Sachiko Nakamori; Ping Du Jiang; Zhi-Hong Yang; Jing Cui; Yu Zhang; Huie Jing; Ann Y. Park; Maria H. Zhu; Sarah E. Weber; Deniz Cagdas; Hassan Abolhassan; Nasrin Behniafard; Margery G. Smelkinson; Qihui Liang; Elif Everest; Julia F. Kun; Alyssa Grogan; Jennifer D. Treat; Christa S. Zerbe; Steven M. Holland; Renu Virmani; Alan T. Remaley; Helen C. Su; Lixin Zheng; Michael J. Lenardo

Journal: biorxiv

PubMed ID: 41743988

Doi: 10.64898/2026.01.26.701509

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Authors: Michael Dominic Sacco; Chunlong Ma; Panagiotis Lagarias; Ang Gao; Julia Alma Townsend; Xiangzhi Meng; Peter Dube; Xiujun Zhang; Yanmei Hu; Naoya Kitamura; Brett Hurst; Bart Tarbet; Michael Thomas Marty; Antonios Kolocouris; Yan Xiang; Yu Chen; Jun Wang

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Authors: Ting-Syuan Lin; Jingting Wan; Jingjin He; Shidong Cui; Yun Huang; Bojian Zhang; Hsi-Yuan Huang; Kexin Zhu; Jihang Chen; Tao Zhang; Shangfu Li; Liao Hu; Yongfei Wang; Hsien-Da Huang; Ping Tang; Yang-Chi-Dung Lin

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody

Authors: Melanie Scherer, Nadia Djabeur, Oliver Siering, Jean-Marc Jeckelmann, Marianne Wyss, Marina Cresci, Morgane Di Palma Subran, Rainer Riedl, Patrick Chames, Christian K Pfaller, Bevan Sawatsky, Dimitrios Fotiadis, Philippe Plattet

Journal: Nature Communications

PubMed ID: 41501035

Doi: 10.1038/s41467-025-67600-z

Products & Services: Monoclonal Antibody Services