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Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

Products & Services: Gene Synthesis

Chemical inhibition of a bacterial immune system

Authors: Zhiyu Zang; Olivia K. Duncan; Dziugas Sabonis; Iana Fedorova; Yun Shi; Gause Miraj; Shuai Le; Jun Deng; Yuhao Zhu; Yanyao Cai; Chengqian Zhang; Garima Arya; Shelley A. H. Dixon; Steven P. Angus; Breck A. Duerkop; Haihua Liang; Robert H. Pepin; Thomas Ve; Joseph Bondy-Denomy; Giedre Tamulaitiene; Joseph P. Gerdt

Journal: Cell Host & Microbe

PubMed ID: 41619738

Doi: 10.1016/j.chom.2026.01.003

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

Enhanced Production of HCV E1E2 Subunit Vaccine Candidates via Protein-Protein Interaction Identification in Glycoengineered CHO cells

Authors: Mina Ying Min Wu; Frances Rocamora; Caressa M. Robinson; Seunghyeon Shin; Eric A. Toth; Thomas R. Fuerst; Svetlana Maurya; Nathan E. Lewis

Journal: biorxiv

PubMed ID: 40475571

Doi: 10.1101/2025.05.20.655202

Structure of the Prenyltransferase in Bifunctional Copalyl Diphosphate Synthase from Penicillium fellutanum Reveals an Open Hexamer Conformation

Authors: Matthew N. Gaynes; Trey A. Ronnebaum; Kollin Schultz; Jacque L. Faylo; Ronen Marmorstein; David W. Christianson

Journal: Journal of structural biology

PubMed ID: 38184156

Doi: 10.1016/j.jsb.2023.108060

Products & Services: Plasmid DNA Preparation

WDR5 remodels NANOG condensates to drive transcriptional programs and sustain stem cell identity

Authors: Duo Wang, Xianle Shi, Jiaying Xie, Lijie Zhao, Bin Wu, Qiman Dong, Yaoguang Huang, Jinlong Suo, Xinyu Wang, Beixuan He, Shukun Yan, Hongjuan Xue, Yuheng Shi, Yingbin Liu, Jianlong Wang, Yong Chen, Yanjing Li

Journal: Nature Communications

PubMed ID: 41565645

Doi: 10.1038/s41467-026-68623-w

Products & Services: Custom DNA/RNA Oligos

An integrated valved microfluidic platform for rapid and simultaneous nucleic acid detection

Authors: Zihan Wang, Fuwan Yang, Shuai Zeng, Rui Sun, Qifei Hu, Yichen Du

Journal: Lab on a chip

PubMed ID: 41439322

Doi: 10.1039/D5LC01096A

Products & Services: Synthetic Guide RNA

Stress controls heterochromatin inheritance via histone H3 ubiquitylation

Authors: Bharat Bhatt, Yi Wei, Ashis Kumar Pradhan, Jothy Dhakshnamoorthy, Martin Zofall, Hua Xiao, Drisya Vijayakumari, Shweta Jain, Hernan Diego Folco, Hongyun Qi, David A Ball, Tatiana S Karpova, David Wheeler, Jiemin Wong, Shiv I S Grewal

Journal: Nature

PubMed ID: 41501458

Doi: 10.1038/s41586-025-09899-8

Products & Services: Protein and Antibody Isolation

Microbiota-induced T cell plasticity enables immune-mediated tumour control

Authors: Tariq A Najar, Yuan Hao, Yuhan Hao, Gabriela Romero-Meza, Alexandra Dolynuk, Emma Almo, Dan R Littman

Journal: Nature

PubMed ID: 41535459

Doi: 10.1038/s41586-025-09913-z

Products & Services: Codon Optimization