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Circulating myeloid-derived suppressor cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosis

Authors: Mari Paz Serrano-Regal, Celia Camacho-Toledano, Inmaculada Alonso-García, María Cristina Ortega, Isabel Machín-Díaz, Rafael Lebrón-Galán, Jénnifer García-Arocha, Leticia Calahorra, Manuel Nieto-Díaz, Diego Clemente

Journal: Neurobiology of Disease

PubMed ID: 40250717

Doi: 10.1016/j.nbd.2025.106919

Products & Services: Peptide Synthesis

Epitope-Optimized Influenza Hemagglutinin Nanoparticle Vaccine Provides Broad Cross- Reactive Immunity against H9N2 Influenza Virus

Authors: Mengchan Hao, Yanhai Wang, Wenxue Yang, Meng Xu, Yiwei Guan, Yuan Zhang, JianJun Chen

Journal: ACS Nano

PubMed ID: 40452158

Doi: 10.1021/acsnano.5c03199

Products & Services: Endotoxin Detection & Removal System

Rice E3 ubiquitin ligase BLAST AND BTH-INDUCED 1 targets jasmonic acid signaling co-repressors to release Myelocytomatosis protein 2 for modulating immune responses against blast fungus

Authors: Yan Bi , Yuqing Yan , Hui Wang , Leeza Tariq , Dayong Li , Fengming Song

Journal: International Journal of Biological Macromolecules

PubMed ID: 40543771

Doi: doi.org/10.1016/j.ijbiomac.2025.145363

Products & Services: Catalog Peptides

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Authors: Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng

Journal: Advanced Science

Doi: doi.org/10.1002/advs.202416809

Products & Services: Peptide Synthesis

Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma

Authors: Juanfen Mo, YuXuan Zhang, Chenxi Cao, WeiLi Zheng, Li Zheng, Xiaoguang Wang, Shiyue Wang, Jiayuan Wu, Yi Bao

Journal: Cell Communication and Signaling

PubMed ID: 40514668

Doi: 10.1186/s12964-025-02289-7

Products & Services: Protein and Antibody Isolation

Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation

Authors: Keke Huang, Yuqing Wu, Yu Kong, Qingyuan Xu, Mingwei Lv, Yirou Zhang, Yiteng Lu, Quanxiao Li, Cheng Li, Wenping Song, Xiaoyi Zhu, Zhenlin Yang, Changchang Xin, Xujiao Zhou, Tianlei Ying, Yanling Wu, Jiaxu Hong

Journal: Cellular & molecular immunology

PubMed ID: 40500403

Doi: 10.1038/s41423-025-01305-7

Products & Services: Protein and Antibody Isolation

An all-silk-based functional system promotes tendon regeneration by regulating the cell fate of TSPCs in an inflammatory microenvironment

Authors: Qingyun Mo, Haotian Zheng, Chuanquan Liu, Yuzhi Sun, Zhicheng Cao, Renwang Sheng, Yanan Zhang, Mingyue Wang, Baian Kuang, Ludvig J Backman, Jiaxiang Li, Wei Zhang, Jialin Chen

Journal: Acta Biomaterialia

PubMed ID: 40409996

Doi: 10.1016/j.actbio.2025.05.040

Products & Services: Recombinant Proteins

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition

Authors: Keyu Kong, Li Liu, Renfang Zhang, Yongyun Chang, Yueming Shao, Chen Zhao, Hua Qiao, Minghao Jin, Xuzhuo Chen, Wentao Shi, Xinru Wu, Wenxuan Fan, Yuehao Hu, Kewei Rong, Pu Zhang, Baixing Li, Jingwei Zhang, Peixiang Ma, Xiaoling Zhang, Huiwu Li, Zanjing Zhai

Journal: Bone Research

PubMed ID: 40461512

Doi: 10.1038/s41413-025-00431-2

Products & Services: Recombinant Proteins

Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy

Authors: Shunqiao Jin; Xiaojiao Liu; Lingqin Cai; Jiayu Yan; Ling Li; Hongjun Dong; Yuxue Gao; Xicong Zhu; Cong Zhang; Xuezhu Xu

Journal: Frontiers in pharmacology

PubMed ID: 39917616

Doi: 10.3389/fphar.2025.1545243

Products & Services: Recombinant Proteins

H19 influenza A virus exhibits species-specific MHC-II receptor usage

Authors: Umut Karakus; Ignacio Mena; Jithesh Kottur; Sara S. El Zahed; Roc o Seoane; Soner Yildiz; Leanne Chen; Magdalena Plancarte; LeAnn Lindsay; Rebecca Halpin; Timothy B Stockwell; David E. Wentworth; Geert-Jan Boons; Florian Krammer; Silke Stertz; Walter Boyce; Robert P de Vries; Aneel K Aggarwal; Adolfo Garc a-Sastre

Journal: Cell Host & Microbe

PubMed ID: 38889725

Doi: 10.1016/j.chom.2024.05.018