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页码: 123/5358 每页显示数量

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Authors: Chunlong Ma; Michael Dominic Sacco; Zilei Xia; George Lambrinidis; Julia Alma Townsend; Yanmei Hu; Xiangzhi Meng; Tommy Szeto; Mandy Ba; Xiujun Zhang; Maura Gongora; Fushun Zhang; Michael Thomas Marty; Yan Xiang; Antonios Kolocouris; Yu Chen; Jun Wang

Journal: ACS central science

PubMed ID: 34341772

Doi: 10.1021/acscentsci.1c00519

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication

Authors: Martina Tuttolomondo; Stephanie Thuy Duong Pham; Mikkel Green Terp; Virginia Cend n Castillo; Nazmie Kalisi; Stefan Vogel; Niels Langkj r; Ulla Melchior Hansen; Helge Thisgaard; Henrik Daa Schr der; Yaseelan Palarasah; Henrik J rn Ditzel

Journal: Molecular therapy. Nucleic acids

PubMed ID: 38939051

Doi: 10.1016/j.omtn.2024.102227

Products & Services: Peptide Synthesis

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication

Journal: Molecular therapy. Nucleic acids

PubMed ID: 38939051

Doi: 10.1016/j.omtn.2024.102227

Products & Services: Peptide Synthesis

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication

Journal: Molecular therapy. Nucleic acids

PubMed ID: 38939051

Doi: 10.1016/j.omtn.2024.102227

Products & Services: Peptide Synthesis

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication

Journal: Molecular therapy. Nucleic acids

PubMed ID: 38939051

Doi: 10.1016/j.omtn.2024.102227

Products & Services: Peptide Synthesis

Eukaryotic Initiation Factor 2 Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens

Authors: Heather A. Walters; Brenda H. Welter; Harrison C. Moss; Martha A. Villano; Ronny Orobio-Hurtado; William J. Sullivan; Lesly A. Temesvari

Journal: mSphere

PubMed ID: 35638357

Doi: 10.1128/msphere.00131-22

Products & Services: Plasmid DNA Preparation

The PYRIN domain is required for TLR4-mediated inflammation by PYHIN family members

Authors: Andrea Iannucci, Davide Lacarbonara, Valeria Caneparo, Federica Castiglioni, Andrea Butticè, Stefano Raviola, Chiara Porta, Riccardo Miggiano, Ivan Zanoni, Marisa Gariglio, Marco De Andrea

Journal: iScience

PubMed ID: 40454096

Doi: 10.1016/j.isci.2025.112413

Products & Services: Mutagenesis Services

Synergistic impact of macrolide resistance and H3N2 infection on M. pneumoniae outbreak in children

Authors: Jiali Chen, Yingdan Wang, Juan Cheng, Yunping Ma, Xin Zhang, Xuezhou Bai, Palizhati Rehati, Huashun Cui, Fan Wu, Qiuhui Pan, Jinghe Huang

Journal: Microbiology Spectrum

PubMed ID: 39998323

Doi: 10.1128/spectrum.01844-24

Products & Services: Gene Synthesis

Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A

Authors: Nitesh Kumar Khandelwal, Meghna Gupta, James E Gomez, Sulyman Barkho, Ziqiang Guan, Ashley Y Eng, Tomohiko Kawate, Sree Ganesh Balasubramani, Andrej Sali, Deborah T Hung, Robert M Stroud

Journal: Nature Communications

PubMed ID: 40169593

Doi: 10.1038/s41467-025-58133-6

Products & Services: Mutagenesis Services

Structural basis for allosteric modulation of M. tuberculosis proteasome core particle

Authors: Madison Turner, Adwaith B. Uday, Algirdas Velyvis, Enrico Rennella, Natalie Zeytuni & Siavash Vahidi

Journal: Nature Communications

PubMed ID: 40169579

Doi: 10.1038/s41467-025-58430-0

Products & Services: Peptide Synthesis