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页码: 19/5356 每页显示数量

Functional characterization of secreted Schistosoma mansoni serpin SmSPI reveals Factor XIIa inhibition as evidenced by biochemical, and human plasma assays and supported by AI-assisted structural modelling

Authors: Lukáš Konečný, Kristýna Peterková, Ingrid Hrachovinová, Alex Loukas, Tomáš Macháček, Jan Dvořák, Lucie Jedličková

Journal: Molecular Therapy

PubMed ID: 41724421

Doi: 10.1016/j.ijpara.2026.104808

Identifying microbial protease allergens through protein language model-guided homology

Authors: Kumar Thurimella, Elena Wu, Chenhao Li, Daniel B Graham, Róisín M Owens, Damian R Plichta, Caroline L Sokol, Ramnik J Xavier, Sergio Bacallado

Journal: Molecular Therapy

PubMed ID: 41722567

Doi: 10.1016/j.cels.2025.101510

Messenger RNA delivery to islet β cells using conjugated lipid nanoparticles

Authors: Jacob R Enriquez, Zhengjie Zhou, Jennifer B Nelson, Fei Huang, Kayla T Figatner, Advaita Chakraborty, Sarida Pratuangtham, Brian Xi, Sarah C May, Matthew V Tirrell, Sarah A Tersey, Yun Fang, Raghavendra G Mirmira

Journal: Molecular Therapy

PubMed ID: 41722565

Doi: 10.1016/j.xcrm.2026.102634

Products & Services: Recombinant Proteins

Identification of xenobiotics interfering with 5α-reductase (SRD5A2) activity

Authors: Jacek Kędzierski, Rianne E van Diest, Julien A Allard, Andreas M Erharter, Alex Odermatt, Martin Smieko

Journal: Molecular Therapy

PubMed ID: 41722875

Doi: 10.1016/j.toxlet.2026.111859

Products & Services: Custom Vector Construction

Targeting Langerhans cells using a modular mannosylated nucleic acid-based vaccine platform

Authors: Simon Christian Vinther, Antonia Resag, Karina Thao Thu Le, Claudia Christine Zelle-Rieser, Helen Strandt, Mette Galsgaard Malle, Stig Hill Christiansen, Barbara Del Frari, Theresia Stigger, Bastian Schilling, Jonas Wohlfarth, Steffen Thiel, Julián Valero, Patrizia Stoitzner, Jørgen Kjems

Journal: Molecular Therapy

PubMed ID: 41713595

Doi: 10.1016/j.jconrel.2026.114741

Products & Services: Custom Vector Construction

The protein phosphatase 2A-B56α complex regulates N-Myc degradation in neuroblastoma

Authors: Brian D Tran, Irene Peris, Ethan Wurman, Averie Huang, Gabrielle Hodges Onishi, Jiang Hu, Rita A Avelar, Erika A Newman, Analisa DiFeo, Caitlin M O'Connor, Goutham Narla

Journal: Molecular Therapy

PubMed ID: 41707997

Doi: 10.1016/j.jbc.2026.111298

Heterologous vs. homologous vaccine regimens: Sulfated lactosyl archaeol (SLA) archaeosome-adjuvanted SARS-CoV-2 spike protein boost following an mRNA/LNP prime induces robust and balanced immune responses

Authors: Tyler M Renner, Gerard Agbayani, Hiva Azizi, Lise Deschatelets, Renu Dudani, Blair A Harrison, Usha D Hemraz, Roger Koukiekolo, Matthew Stuible, Yves Durocher, Michael J McCluskie, Bassel Akache

Journal: Vaccine

PubMed ID: 41505874

Doi: 10.1016/j.vaccine.2025.128182

Products & Services: Codon Optimization Gene Synthesis

High-yield production of hydroxytyrosol through metabolic engineering of Yarrowia lipolytica

Authors: Bihuan Chen, Yuanyuan Wang, Danlin Wang, Yina Wang, Xiangyu Liu, Guanghui Zhang, Shengchao Yang

Journal: Synthetic and systems biotechnology

PubMed ID: 41766957

Doi: 10.1016/j.synbio.2026.01.022

Products & Services: Gene Synthesis Codon Optimization

Abstract Supplement Abstracts from AIDS 2022 the 24th International AIDS Conference, 29 July 2 August 2022, Montr al, Canada & Virtual

Authors:

Journal: Journal of the International AIDS Society

PubMed ID: 35916394

Doi: 10.1002/jia2.25935

Humanization and engineering of protective antibodies targeting severe fever with thrombocytopenia syndrome virus Gn protein

Authors: Xuanxiu Ren, Wei Deng, Feiyang Yu, Wenhua Kuang, Heya Na, Shangyu Yang, Jiawen Sun, Jianlun Xu, Bo Shu, Sheng Cao, Xianliang Ke, Zengqin Deng, Yun-Jia Ning, Haiyan Zhao

Journal: Cell Reports

PubMed ID: 41671090

Doi: 10.1016/j.celrep.2026.116936

Products & Services: Protein and Antibody Isolation