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页码: 135/5356 每页显示数量

Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis

Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang

Journal: JACS Au

Doi: doi/10.1021/jacsau.5c00067

Products & Services: Protein Electrophoresis and Western

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants

Authors: Shouya Feng, Matthew C Wierzbowski, Katja Hrovat-Schaale, Andreas Dumortier, Yaoyuan Zhang, Maria Zyulina, Paul J Baker, Thomas Reygaerts, Annemarie Steiner, Dominic De Nardo, Dhanya Lakshmi Narayanan, Florian Milhavet, Alberto Pinzon-Charry, Juan Ignacio Arostegui, Raju P Khubchandani, Matthias Geyer, Guilaine Boursier, Seth L Masters

Journal: nature immunology

PubMed ID: 39930093

Doi: 10.1038/s41590-025-02088-9

Products & Services: Mutagenesis Services

GLP1 alleviates oleic acid-propelled lipocalin-2 generation by tumor-infiltrating CD8+ T cells to reduce polymorphonuclear MDSC recruitment and enhances viral immunotherapy in pancreatic cancer

Authors: Jingyi Wu, Peng Qian, Yifeng Han, Chuning Xu, Mao Xia, Ping Zhan, Jiwu Wei, Jie Dong

Journal: Cellular & molecular immunology

PubMed ID: 39910336

Doi: 10.1038/s41423-025-01260-3

Products & Services: Custom Vector Construction

Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

Authors: Wenjing Zhu; Zhengjie Zhang; Xinyuan Wang

Journal: Frontiers in molecular biosciences

PubMed ID: 40191037

Doi: 10.3389/fmolb.2025.1552360

AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens

Authors: Chenkai Li; Darcy Sutherland; S. Austin Hammond; Chen Yang; Figali Taho; Lauren Bergman; Simon Houston; Ren L. Warren; Titus Wong; Linda M. N. Hoang; Caroline E. Cameron; Caren C. Helbing; Inanc Birol

Journal: BMC Genomics

PubMed ID: 35078402

Doi: 10.1186/s12864-022-08310-4

Products & Services: Peptide Synthesis

A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545

The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Authors: Yijian Qiu; Olivia T. Stamatatos; Qingting Hu; Jed de Ruiter Swain; Suzanne Russo; Ava Sann; Ana S. H. Costa; Sara Violante; David L. Spector; Justin R. Cross; Michael J. Lukey

Journal: Nature metabolism

PubMed ID: 39192144

Doi: 10.1038/s42255-024-01104-w

A coronavirus assembly inhibitor that targets the viral membrane protein

Authors: Manon Laporte; Dirk Jochmans; Doroth e Bardiot; Lowiese Desmarets; Oliver J. Debski-Antoniak; Giulia Mizzon; Rana Abdelnabi; Pieter Leyssen; Winston Chiu; Zhikuan Zhang; Norimichi Nomura; Sandro Boland; Umeharu Ohto; Yannick Stahl; Jurgen Wuyts; Steven De Jonghe; Annelies Stevaert; Martijn J. van Hemert; Brenda W. Bontes; Patrick Wanningen; G. J. Mirjam Groenewold; Aneta Zegar; Katarzyna Owczarek; Sanjata Joshi; Mohamed Koukni; Philippe Arzel; Hugo Klaassen; Jean-Christophe Vanherck; Ilse Vandecaetsbeek; Niels Cremers; Kim Donckers; Thibault Francken; Tina Van Buyten; Jasper Rymenants; Joost Schepers; Krzysztof Pyrc; Rolf Hilgenfeld; Jean Dubuisson; Berend-Jan Bosch; Frank Van Kuppeveld; Cecilia Eydoux; Etienne Decroly; Bruno Canard; Lieve Naesens; Birgit Weynand; Eric J. Snijder; Sandrine Belouzard; Toshiyuki Shimizu; Ralf Bartenschlager; Daniel L. Hurdiss; Arnaud Marchand; Patrick Chaltin; Johan Neyts

Journal: Nature

PubMed ID: 40140569

Doi: 10.1038/s41586-025-08773-x

A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545

A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545