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页码: 122/5356 每页显示数量

A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication

Authors: Martina Tuttolomondo; Stephanie Thuy Duong Pham; Mikkel Green Terp; Virginia Cend n Castillo; Nazmie Kalisi; Stefan Vogel; Niels Langkj r; Ulla Melchior Hansen; Helge Thisgaard; Henrik Daa Schr der; Yaseelan Palarasah; Henrik J rn Ditzel

Journal: Molecular therapy. Nucleic acids

PubMed ID: 38939051

Doi: 10.1016/j.omtn.2024.102227

Products & Services: Peptide Synthesis

Eukaryotic Initiation Factor 2 Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens

Authors: Heather A. Walters; Brenda H. Welter; Harrison C. Moss; Martha A. Villano; Ronny Orobio-Hurtado; William J. Sullivan; Lesly A. Temesvari

Journal: mSphere

PubMed ID: 35638357

Doi: 10.1128/msphere.00131-22

Products & Services: Plasmid DNA Preparation

Polyarginine Peptide R11 Actin Interaction Induces a Domino Effect on Cytoskeleton Remodeling to Suppress Bladder Cancer Metastasis

Authors: Zhenghong Liu; Chuanzan Zhou; Wentao Xu; Dahong Zhang; Bin Zheng; Facai Zhang; Xiaowen Qin; Heng Wang; Yixuan Mou; Yang Liu; Haichang Li; Jing Quan; Li Sun; Yiyang Chen; Chenkai Wang; Xuanyi Zhou; Xinyi Chen; Hong Tang; Dingyi Liu; Wenyan Zuo; Dechao Feng; Pu Zhang; Qi Zhang

Journal: RESEARCH

PubMed ID: 41624794

Doi: 10.34133/research.1109

Products & Services: Protein Electrophoresis and Western

Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A

Authors: Nitesh Kumar Khandelwal, Meghna Gupta, James E Gomez, Sulyman Barkho, Ziqiang Guan, Ashley Y Eng, Tomohiko Kawate, Sree Ganesh Balasubramani, Andrej Sali, Deborah T Hung, Robert M Stroud

Journal: Nature Communications

PubMed ID: 40169593

Doi: 10.1038/s41467-025-58133-6

Products & Services: Mutagenesis Services

Structural basis for allosteric modulation of M. tuberculosis proteasome core particle

Authors: Madison Turner, Adwaith B. Uday, Algirdas Velyvis, Enrico Rennella, Natalie Zeytuni & Siavash Vahidi

Journal: Nature Communications

PubMed ID: 40169579

Doi: 10.1038/s41467-025-58430-0

Products & Services: Peptide Synthesis

Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance

Authors: Amanda L. Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R. Tuttle, Chao Liu, Jiaming Li, Ji Sung Park, Samuel M. Hoenig, Marco Barone, Airi Furui, Andrea Mattevi & Brian B. Liau

Journal: Nature Communications

PubMed ID: 40175327

Doi: 10.1038/s41467-025-57477-3

Products & Services: Peptide Synthesis

CodonTransformer: a multispecies codon optimizer using context-aware neural networks

Authors: Adibvafa Fallahpour, Vincent Gureghian, Guillaume J. Filion, Ariel B. Lindner & Amir Pandi

Journal: Nature Communications

PubMed ID: 40180930

Doi: 10.1038/s41467-025-58588-7

Products & Services: Molecular Biology Tools

Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine

Authors: Kalvis Brangulis, Jill Malfetano, Ashley L. Marcinkiewicz, Alan Wang, Yi-Lin Chen, Jungsoon Lee, Zhuyun Liu, Xiuli Yang, Ulrich Strych, Dagnija Tupina, Inara Akopjana, Maria-Elena Bottazzi, Utpal Pal, Ching-Lin Hsieh, Wen-Hsiang Chen & Yi-Pin Lin

Journal: Nature Communications

PubMed ID: 40189575

Doi: 10.1038/s41467-025-58182-x

Products & Services: Gene Synthesis

Modified pegRNAs mitigate scaffold-derived prime editing by-products

Authors: Panagiotis Antoniou, Louis Dacquay, Hanna Mårtensson, Katja Madeyski-Bengtson, Anna-Lena Loyd, Anna Shiriaeva, Euan Gordon, Salman Mustfa, George Thom, Pei-Pei Hsieh, Saša Šviković, Mike Firth, Nina Akrap, Marcello Maresca & Martin Peterka

Journal: Nature Communications

PubMed ID: 40204736

Doi: 10.1038/s41467-025-58653-1

Products & Services: Gene Synthesis

Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5

Authors: Zhefan Stephen Chen, Shaohong Isaac Peng, Lok I Leong, Terence Gall-Duncan, Nathan Siu Jun Wong, Tsz Ho Li, Xiao Lin, Yuming Wei, Alex Chun Koon, Junzhe Huang, Jacquelyne Ka-Li Sun, Clinton Turner, Lynette Tippett, Maurice A. Curtis, Richard L. M. Faull, Kin Ming Kwan, Hei-Man Chow, Ho Ko, Ting-Fung Chan, Kevin Talbot, Christopher E. Pearson & Ho Yin Edwin Chan

Journal: Nature Communications

PubMed ID: 40204699

Doi: 10.1038/s41467-025-58618-4

Products & Services: Gene Synthesis