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Fused exosomal targeted therapy in periprosthetic osteolysis through regulation of bone metabolic homeostasis

Authors: Tianliang Ma, Qimeng Liu, Zheyu Zhang, Jiangyu Nan, Guanzhi Liu, Yute Yang, Yihe Hu, Jie Xie

Journal: Bioactive Materials

PubMed ID: 40248188

Doi: doi.org/10.1016/j.bioactmat.2025.04.006

Products & Services: Protein and Antibody Isolation

Identification of RC3H1 as antiviral host factor binding to the non-structural protein 1 of Influenza A virus via a 3-stage computational pipeline and cell-based analysis

Authors: Swee Teng Teo , Shamima Rashid , Kong Yen Liew , Kah Man Lai , Teng Ann Ng , Jifeng Jiao , Chee Keong Kwoh , Yee-Joo Tan

Journal: Virology Journal

PubMed ID: 40287742

Doi: 10.1186/s12985-025-02746-2

Products & Services: ORF cDNA Clones/MolecularCloud

Virus glycoprotein nanodisc platform for vaccine design

Authors: Kimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief

Journal: biorxiv

PubMed ID: 40666859

Doi: 10.1101/2025.05.02.651272

Products & Services: Catalog Antibodies

Polyarginine Peptide R11 Actin Interaction Induces a Domino Effect on Cytoskeleton Remodeling to Suppress Bladder Cancer Metastasis

Authors: Zhenghong Liu; Chuanzan Zhou; Wentao Xu; Dahong Zhang; Bin Zheng; Facai Zhang; Xiaowen Qin; Heng Wang; Yixuan Mou; Yang Liu; Haichang Li; Jing Quan; Li Sun; Yiyang Chen; Chenkai Wang; Xuanyi Zhou; Xinyi Chen; Hong Tang; Dingyi Liu; Wenyan Zuo; Dechao Feng; Pu Zhang; Qi Zhang

Journal: RESEARCH

PubMed ID: 41624794

Doi: 10.34133/research.1109

Products & Services: Protein Electrophoresis and Western

Phosphorylation dependent charge block regulate the relaxation of nuclear speckle networks

Authors: Mengjun Zhang, Zhuang Gu, Yingtian Sun, Yichen Dong, Junlin Chen, Li Shu, Suibin Ma, Jierui Guo, Yuhang Liang, Qingming Qu, Ning Fang, Chuan-Qi Zhong, Yifan Ge, Zhongwen Chen, Shaohui Huang, Xin Zhang, Bo Wang

Journal: Mol Cell

PubMed ID: 40233760

Doi: 10.1016/j.molcel.2025.03.016

Products & Services: Protein and Antibody Isolation

Inhibitor-based modulation of huntingtin aggregation mechanisms mitigates ﬁbrilinduced cellular stress

Authors: Greeshma Jain, Marina Trombetta-Lima, Irina Matlahov, Hennrique Taborda Ribas, Tingting Chen, Raffaella Parlato, Giuseppe Portale, Amalia M. Dolga & Patrick C. A. van der Wel

Journal: Nat Commun

PubMed ID: 40234398

Doi: 10.1038/s41467-025-58691-9

Products & Services: Plasmid DNA Preparation Catalog Antibodies

Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease

Authors: Emre Fertan; Jeff Y. L. Lam; Giulia Albertini; Maarten Dewilde; Yunzhao Wu; Oluwatomi E. S. Akingbade; Dorothea B ken; Elizabeth A. English; Bart De Strooper; David Klenerman

Journal: Alzheimer's & Dementia

PubMed ID: 40237235

Doi: 10.1002/alz.70086

Products & Services: Protein and Antibody Isolation

S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2

Authors: Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang

Journal: Advanced Science

PubMed ID: 40171943

Doi: 10.1002/advs.202416481

Products & Services: Protein and Antibody Isolation

A predatory gene drive for targeted control of self-transmissible plasmids

Authors: Ryan Tsoi, Hye-In Son, Grayson S Hamrick, Katherine Tang, Jonathan H Bethke, Jia Lu, Rohan Maddamsetti, Lingchong You