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页码: 117/5356 每页显示数量

Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori

Authors: Md. Nahian; Md. Rasel Khan; Fabiha Rahman; Hossain Mohammed Reza; Imren Bayil; Tanjum Ahmed Nodee; Tabassum Basher; Mostafizur Rahaman Sany; Rabeya Najnin Munmun; S. M. Ariful Habib; Lincon Mazumder; Mrityunjoy Acharjee; Abu Tayab Moin; Abu Tayab Moin; Abu Tayab Moin

Journal: PLoS ONE

PubMed ID: 39919064

Doi: 10.1371/journal.pone.0318750

De Novo Multi Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Authors: Xiaojuan Li; Haifan Gong; Yue Wang; Yinuo Zhao; Lixiang Li; Peijing Bao; Qingzhou Kong; Jialu Fu; Boyao Wan; Yumeng Zhang; Jinghui Zhang; Jiekun Ni; Zhongxue Han; Xueping Nan; Kunping Ju; Longfei Sun; Yuerui Ma; Huijun Chang; Mengqi Zheng; Yanbo Yu; Xiaoyun Yang; Xiuli Zuo; Haina Wang; Yanqing Li

Journal: Advanced Science

PubMed ID: 41801219

Doi: 10.1002/advs.202515835

Products & Services: Peptide Synthesis

SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling

Authors: Imene Hamaidi; Pingyan Cheng; Soo Young Jun; Alak Manna; Min-Hsuan Wang; Anh Nguyen; Ismail Can; Min G. Zhang; Odesha O. Taylor; Luis Uriel Lopez Bailon; Bin Fang; Bradford Perez; Ben C. Creelan; Andriy Marusyk; Dongjun Shin; Tae Hyun Hwang; Anders E. Berglund; Virginia S. Shapiro; Haitao M. Ji; Jos R. Conejo-Garcia; Sungjune Kim

Journal: nature immunology

PubMed ID: 41611868

Doi: 10.1038/s41590-025-02377-3

Products & Services: Custom Vector Construction

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Authors: Chunlong Ma; Michael Dominic Sacco; Zilei Xia; George Lambrinidis; Julia Alma Townsend; Yanmei Hu; Xiangzhi Meng; Tommy Szeto; Mandy Ba; Xiujun Zhang; Maura Gongora; Fushun Zhang; Michael Thomas Marty; Yan Xiang; Antonios Kolocouris; Yu Chen; Jun Wang

Journal: ACS central science

PubMed ID: 34341772

Doi: 10.1021/acscentsci.1c00519

Virus glycoprotein nanodisc platform for vaccine design

Authors: Kimmo Rantalainen; Alessia Liguori; Gabriel Ozorowski; Claudia Flynn; Jon M. Steichen; Olivia Swanson; Patrick J. Madden; Sabyasachi Baboo; Swastik Phulera; Anant Gharpure; Danny Lu; Oleksandr Kalyuzhniy; Patrick Skog; Sierra Terada; Monolina Shil; Jolene K. Diedrich; Erik Georgeson; Ryan Tingle; Saman Eskandarzadeh; Wen-Hsin Lee; Nushin Alavi; Diana Goodwin; Michael Kubitz; Sonya Amirzehni; Sunny Himansu; Devin Sok; Jeong Hyun Lee; John R. Yates; James C. Paulson; Shane Crotty; Torben Schiffner; Andrew B. Ward; William R. Schief

Journal: biorxiv

PubMed ID: 40666859

Doi: 10.1101/2025.05.02.651272

Products & Services: Catalog Antibodies

Stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids

Authors: Jennifer M. Podgorski, Joshua Podgorski, Lawrence Abad, Deborah Jacobs-Sera, Krista G. Freeman, Colin Brown, Graham F. Hatfull, Antoni Luque & Simon J. White

Journal: Nature Communications

PubMed ID: 40175362

Doi: 10.1038/s41467-025-58298-0

Products & Services: Gene Synthesis

Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment

Authors: Zhuoyao Chen, Gamma Chi, Timea Balo, Xiangrong Chen, Beatriz Ralsi Montes, Steven C. Clifford, Vincenzo D’Angiolella, Timea Szabo, Arpad Kiss, Tibor Novak, András Herner, András Kotschy & Alex N. Bullock

Journal: Nature Communications

PubMed ID: 40175372

Doi: 10.1038/s41467-025-58350-z

Products & Services: Gene Synthesis

Enhanced the Trans-Cleavage Activity of CRISPR-Cas12a Using Metal-Organic Frameworks as Stimulants for Efficient Electrochemical Sensing of Circulating Tumor DNA

Authors: Shuai Wu, Yincheng Liu, Tianyu Zeng, Tianci Zhou, Yanting Sun, Ying Deng, Juan Zhang, Genxi Li, Yongmei Yin

Journal: Advanced Science

PubMed ID: 40184611

Doi: 10.1002/advs.202417206

Products & Services: Gene Synthesis

CD22 TCR-engineered T cells exert antileukemia cytotoxicity without causing inflammatory responses

Authors: Kilyna A Nguyen, Zhihui Liu, John S Davies, Crystal P McIntosh, Lindsey M Draper, Scott M Norberg, Zachary Rae, Sooraj R Achar, Gregoire Altan-Bonnet, Ling Zhang, Xiaolin Wu, Thomas J Meyer, Michael C Kelly, Naomi Taylor, Christian S Hinrichs, Kazusa Ishii

Journal: SCIENCE ADVANCES

PubMed ID: 40203088

Doi: 10.1126/sciadv.adq4297

Products & Services: Gene Synthesis

Engineered depalmitoylases enable selective manipulation of protein localization and function

Authors: Srinidhi Jayaraman, Audrey Kochiss, Thy-Lan Alcalay, Pedro J. del Rivero Morfin & Manu Ben-Johny

Journal: Nature Communications

PubMed ID: 40223127

Doi: 10.1038/s41467-025-58908-x

Products & Services: Catalog Antibodies