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The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance

Authors: Rujia Si, Yihan Zhang, Bowen Hu, Yuxin Du, Dan Zou, Shaodi Wen, Xiaoyue Du, Xin Chen, Chen Peng, Shulei Fu, Shiying Zhu, Fan Du, Xiaofeng Sha, Ning Ding, Cong Xu, Bo Shen

Journal: Anti-Cancer Agents in Medicinal Chemistry

Doi: 10.2174/0118715206430859250915050817

Products & Services: Protein Electrophoresis and Western

Provision of a Redox Donor to Oxy-Ferrous PrnB Is Required for Pyrrolnitrin Synthesis

Authors: R Brian McMillan, Hannah E Gering, Anastasia E Ledinina, Shan Xue, Sayali Karandikar, Shuangjun Lin, Garim You, Tzu-Yu Chen, Yisong Guo, Wei-Chen Chang, Thomas M Makris

Journal: Biochemistry

PubMed ID: 40827054

Doi: 10.1021/acs.biochem.5c00263

Products & Services: Gene Synthesis PCR Cloning and Subcloning Codon Optimization

Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity

Authors: Yujiao Zu; Ling Zhao; Lei Hao; Yehia Mechref; Masoud Zabet-Moghaddam; Peter A. Keyel; Mehrnaz Abbasi; Dayong Wu; John A. Dawson; Ruiwen Zhang; Shufang Nie; Naima Moustaid-Moussa; Mikhail G. Kolonin; Alexes C. Daquinag; Luis Brandi; Irfan Warraich; Susan K. San Francisco; Xiaocun Sun; Zhaoyang Fan; Shu Wang

Journal: Journal of controlled release : official journal of the Controlled Release Society

PubMed ID: 33766692

Doi: 10.1016/j.jconrel.2021.03.022

Products & Services: Peptide Synthesis

A rationally designed 18-amino acid peptide with potential as GLP-1 receptor agonist

Authors: Aditi Singh; Sucharita Shadangi; Soumendra Rana

Journal: Frontiers in pharmacology

PubMed ID: 42244872

Doi: 10.3389/fphar.2026.1789257

Mining the CD4 antigen repertoire for next-generation tuberculosis vaccines

Authors: Samuel J Vidal, Ninaad Lasrado, Lisa H Tostanoski, Jayeshbhai Chaudhari, Esther R Mbiwan, Ganad D Neka, Ellis A Strutton, Alejandro A Espinosa Perez, Daniel Sellers, Julia Barrett, Michelle Lifton, Shoko Wakabayashi, Behnaz Eshaghi, Erica N Borducchi, Malika Aid, Wenjun Li, Thomas J Scriba, Ana Jaklenec, Robert Langer, Dan H Barouch

Journal: Cell

PubMed ID: 40957415

Doi: 10.1016/j.cell.2025.08.027

Products & Services: Peptide Services Peptide Synthesis

Intrinsically disordered region of Clr4/Suv39 regulates its enzymatic activity and ensures heterochromatin spreading

Authors: Rinko Nakamura, Aki Hayashi, Reiko Nakagawa, Yuriko Yoshimura, Naoki Horikoshi, Hitoshi Kurumizaka, Jun-Ichi Nakayama

Journal: Nucleic Acids Research

PubMed ID: 40923761

Doi: 10.1093/nar/gkaf878

Computational design of potent and selective binders of BAK and BAX

Authors: Stephanie Berger, Erinna F Lee, Tiffany J Harris, Sharon Tran, Asim K Bera, Lauren Arguinchona, Alex Kang, Banumathi Sankaran, Sila Kasapgil, Michelle S Miller, Sean Smyth, Mariam Lutfi, Rachel T Uren, Ruth M Kluck, Peter M Colman, Walter D Fairlie, Peter E Czabotar, David Baker, Richard W Birkinshaw

Journal: SCIENCE ADVANCES

PubMed ID: 40911686

Doi: 10.1126/sciadv.adt4170

Microgel Aspect Ratio Influences Injectable Granular Hydrogel Scaffold Pore Structure and Cellular Invasion for Tissue Repair

Authors: Gabriel J Rodriguez-Rivera, Siddharth Sharma, Chima V Maduka, Sara Boyd, Amy R Perry, Nikolas Di Caprio, Lindsay Riley, Connor E Miksch, Daeyeon Lee, Tatiana Segura, David Issadore, Jason A Burdick

Journal: Advanced Science

PubMed ID: 40940307

Doi: 10.1002/advs.202511513

Products & Services: Peptide Services

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Authors: Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang

Journal: Advanced Science

PubMed ID: 40940305

Doi: 10.1002/advs.202503534

Products & Services: Gene Services

Neofunctionalized RGF pathways drive haustorial organogenesis in parasitic plants

Authors: Maxwell R Fishman, Anne Greifenhagen, Takanori Wakatake, Anuphon Laohavisit, Ryoko Hiroyama, Sachiko Masuda, Arisa Shibata, Satoko Yoshida, Ken Shirasu

Journal: SCIENCE ADVANCES

PubMed ID: 40961186

Doi: 10.1126/sciadv.adw3965

Products & Services: Gene Services