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页码: 52/5357 每页显示数量

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade

Authors: Adam J. Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna DeVries, Paul Castillo, Rishabh Lohray, Michael K. Rooney, Benjamin R. Schrank, Yifan Wang, Yifan Ma, D3CODE Team, …Steven H. Lin

Journal: Nature

PubMed ID: 41125896

Doi: 10.1038/s41586-025-09655-y

Combining evidence from human genetic and functional screens to identify pathways altering obesity and fat distribution

Authors: Nikolas A. Baya; Ilknur Sur Erdem; Samvida S. Venkatesh; Saskia Reibe; Philip D. Charles; Elena Navarro-Guerrero; Barney Hill; Frederik H. Lassen; Melina Claussnitzer; Duncan S. Palmer; Cecilia M. Lindgren

Journal: American journal of human genetics

PubMed ID: 40912257

Doi: 10.1016/j.ajhg.2025.08.013

Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer

Authors: Jin Heon Jeon; Mark D. Slayton; Ben Krinkel; Olamide Animasahun; Ajay Shankaran; Fulei Wuchu; Minal Nenwani; Zackariah Farah; Julia Burke; Abhinav Achreja; Brisilda Nilaj; Kerslee Kohagen; Yi-Hsien Eu; Alyssa Rosenfeld; Mason Collard; Liwei Bao; Xu Cheng; Celina Kleer; Christopher Squire; Kerry Loomes; Deepak Nagrath; Sofia D. Merajver

Journal: Cancer & Metabolism

PubMed ID: 41088330

Doi: 10.1186/s40170-025-00410-5

Insights into next generation sequencing guided antibody selection strategies

Authors: M. Frank Erasmus; Fortunato Ferrara; Sara D Angelo; Laura Spector; Camila Leal-Lopes; Andr A. Teixeira; Jesper S rensen; Suhani Nagpal; Kathryn Perea-Schmittle; Alok Choudhary; William Honnen; David Calianese; Luis Antonio Rodriguez Carnero; Simon Cocklin; Victor Greiff; Abraham Pinter; Andrew R. M. Bradbury

Journal: Scientific REPORTS

PubMed ID: 37884618

Doi: 10.1038/s41598-023-45538-w

Products & Services: Catalog Antibodies

Insights into next generation sequencing guided antibody selection strategies

Journal: Scientific REPORTS

PubMed ID: 37884618

Doi: 10.1038/s41598-023-45538-w

Products & Services: Catalog Antibodies

Protocol for production and characterization of SARS-CoV-2 PL pro in Escherichia coli

Authors: Anna De Falco; Rebecca Greene-Cramer; Ben A. Shurina; Suren Zakian; Thomas B. Acton; Theresa A. Ramelot; Gaetano T. Montelione

Journal: STAR Protocols

PubMed ID: 40682779

Doi: 10.1016/j.xpro.2025.103952

An AI-derived peptide PCa2 suppresses pancreatic cancer growth via modulation of the ErbB/PI3K/AKT/mTOR/MYC signaling axis

Authors: Weimin Zuo; Siyuan Luo; Haixin Qin; Koon Ho Wong; Shirley W. I. Siu; Alexandre K. Tashima; Yehuda G. Assaraf; Hang Fai Kwok

Journal: Cell Communication and Signaling : CCS

PubMed ID: 41957678

Doi: 10.1186/s12964-026-02856-6

Products & Services: Peptide Synthesis

A D-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis

Authors: Michael J. Pepi; Shibin Chacko; Gary M. Marqus; Vinayak Singh; Zhe Wang; Kyle Planck; Ryan T. Cullinane; Penchala N. Meka; Deviprasad R. Gollapalli; Thomas R. Ioerger; Kyu Y. Rhee; Gregory D. Cuny; Helena I.M. Boshoff; Lizbeth Hedstrom

Journal: ACS Infectious Diseases

PubMed ID: 35015509

Doi: 10.1021/acsinfecdis.1c00461

Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries

Authors: Mark A. Tornetta; Brian P. Whitaker; Olivia M. Cantwell; Peter N. Haytko; Eileen D. Pisors; Fulai Zhou; Mark L. Chiu

Journal: Antibodies

PubMed ID: 40843683

Doi: 10.3390/antib14030071

Development of Pyrimido Pyridazine Analogs through Increased Whole Cell Target Engagement of the Dihydropteroate Synthase Pterin Binding Site in Gram-Negative Bacteria

Authors: Hannah E. Snoke; Stephanie M. Reeve; Suresh Dharuman; Miranda J. Wallace; Victoria C. Loudon; Ying Zhao; John J. Bowling; Patricia A. Murphy; Brett Waddell; Robin B. Lee; J rgen B. Bulitta; Richard E. Lee

Journal: ACS Infectious Diseases

PubMed ID: 41116192

Doi: 10.1021/acsinfecdis.5c00635