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AMPGen: an evolutionary information-reserved and diffusion-driven generative model for de novo design of antimicrobial peptides

Authors: Shuwen Jin, Zihan Zeng, Xiyan Xiong, Baicheng Huang, Li Tang, Hongsheng Wang, Xiao Ma, Xiaochun Tang, Guoqing Shao, Xingxu Huang, Feng Lin

Journal: Communications Biology

PubMed ID: 40447738

Doi: 10.1038/s42003-025-08282-7

Products & Services: Peptide Synthesis

Constitutive arrestin recruitment by orphan GPR52 via an atypical binding mode

Authors: Xi Lin, Xiaohu Wei, Ning Pu, Ling Wang, Zhibin Zhang, Cuixia Li, Yang Yue, Junlin Liu, Qiwen Tan, Qianqian Sun, Fei Xu

Journal: Cell Research

PubMed ID: 40813798

Doi: 10.1038/s41422-025-01165-w

Products & Services: Protein and Antibody Isolation

E. coli-mediated expedient biosynthesis of biotin-labeled ubiquitin probe enables activity-based profiling of deubiquitinases in cytoplasmic and nuclear compartments

Authors: Shuai Peng, Shaowen Wang, Xiaotong Liu, Hongrui Xu, Guoqiang Xu, Jia-bin Li

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.111760

Products & Services: Codon Optimization Gene Synthesis PCR Cloning and Subcloning

Retrograde transport of neurotrophin receptor TrkB-FL inducedby excitotoxicity regulates Golgi stability and is a target forstroke neuroprotection

Authors: Gema María Esteban-Ortega, Elena Torres-Campos, Margarita Díaz-Guerra

Journal: Cell death & disease

PubMed ID: 40883288

Doi: 10.1038/s41419-025-07990-6

Products & Services: Peptide Synthesis Protein and Antibody Isolation

Viral evolution prediction identifies broadly neutralizing antibodies to existing and rospective SARS-CoV-2 variants

Authors: Fanchong Jian, Anna Z Wec, Leilei Feng, Yuanling Yu, Lei Wang, Peng Wang, Lingling Yu, Jing Wang, Jacob Hou, Daniela Montes Berrueta, Diana Lee, Tessa Speidel, LingZhi Ma, Thu Kim, Ayijiang Yisimayi, Weiliang Song, Lu Liu, Sijie Yang, Xiao Niu, Tianhe Xiao, Ran An, Yao Wang, Fei Shao, Youchun Wang, Simone Pecetta, Xiangxi Wang, Laura M Walker, Yunlong Cao

Journal: Nature Microbiology

PubMed ID: 40494884

Doi: 10.1038/s41564-025-02030-7

Products & Services: Gene Synthesis Codon Optimization

USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4

Authors: Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Jiao Yang, Lijuan Wang, Lijun Dong, Wei Xie, Lin Liu

Journal: Nature Communications

PubMed ID: 40750602

Doi: 10.1038/s41467-025-62303-x.

Products & Services: Polyclonal Antibody Services

GTP hydrolysis triggers membrane remodeling by AMPH-1

Authors: Wei Gai https://orcid.org/0009-0005-5681-7380, Yuhang Wang https://orcid.org/0000-0002-8048-138X, Brianna Martin, Junjie Zhang https://orcid.org/0000-0002-7912-0819, Chavela M. Carr https://orcid.org/0009-0005-1292-1119, and Hays S. Rye

Journal: SCIENCE ADVANCES

PubMed ID: 40749062

Doi: 10.1126/sciadv.ads9443

Products & Services: Protein and Antibody Isolation

The EMC acts as a chaperone for membrane proteins

Authors: Carolin J Klose, Kevin M Meighen-Berger, Martin Kulke, Marina Parr, Barbara Steigenberger, Martin Zacharias, Dmitrij Frishman, Matthias J Feige

Journal: Nature Communications

PubMed ID: 40753078

Doi: 10.1038/s41467-025-62109-x

Products & Services: Catalog Antibodies

IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes

Authors: Lei Bao, Christian F Guerrero Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Aadil Ahmed, N Ishii, T Hashimoto, Bethany E Perez White, Stefan Green, Kevin Kunstman, Nicole C Nowak, Connor Cole, Virgilia Macias, Maria Sverdlov, M Allen McAlexander, Christopher McCrae, Christopher D Nazaroff, Enno Schmidt, Kyle T Amber

Journal: Nature Communications

PubMed ID: 40769980

Doi: 10.1038/s41467-025-62495-2.

Products & Services: Antibody Modification and Purification Services

Self-splicing RNA circularization facilitated by intact group I and II introns

Authors: Yong Shen, Bohan Li, Lei Dong, Wei Tang, Jiwu Ren, Feng Chen, Wenjuan Zheng, Ying Yu, Lu Gao, Wensheng Wei

Journal: Nature Communications

PubMed ID: 40784880

Doi: 10.1038/s41467-025-62607-y.

Products & Services: Protein Electrophoresis and Western