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页码: 90/5356 每页显示数量
PPP2R1A mutations portend improved survival after cancer immunotherapy
Authors: Yibo Dai, Anne Knisely, Mitsutake Yano, Minghao Dang, Emily M Hinchcliff, Sanghoon Lee, Annalyn Welp, Manoj Chelvanambi, Matthew Lastrapes, Heng Liu, Zhe Yuan, Chen Wang, Hao Nie, Stephanie Jean, Luis J Montaner, Jiakai Hou, Ami Patel, Shrina Patel, Bryan Fellman, Ying Yuan, Baohua Sun, Renganayaki Krishna Pandurengan, Edwin Roger Parra Cuentas, Joseph Celestino, Yan Liu, Jinsong Liu, R Tyler Hillman, Shannon N Westin, Anil K Sood, Pamela T Soliman, Aaron Shafer, Larissa A Meyer, David M Gershenson, David Vining, Dhakshinamoorthy Ganeshan, Karen Lu, Jennifer A Wargo, Weiyi Peng, Rugang Zhang, Linghua Wang, Amir A Jazaeri
Journal: Nature
PubMed ID: 40604275
Doi: 10.1038/s41586-025-09203-8
Products & Services: Gene Synthesis   
Induction of lung mucosal immunity by a next-generation inhaled aerosol COVID-19 vaccine: an open-label, multi-arm phase 1 clinical trial
Authors: Mangalakumari Jeyanathan, Sam Afkhami, Michael R D'Agostino, Imran Satia, Dominik K Fritz, Kate Miyasaki, Jann C Ang, Anna Zganiacz, Karen J Howie, Marilyn Swinton, Emilio Aguirre, Michael B Zheng, Natallia Kazhdan, Anna Dvorkin-Gheva, Lawrence Mbuagbaw, Maria Fe C Medina, Nermin Diab, Danica L Brister, Gail M Gauvreau, Brian D Lichty, Matthew S Miller, Fiona Smaill, Zhou Xing
Journal: Nature Communications
PubMed ID: 40603330
Doi: 10.1038/s41467-025-60726-0
Products & Services: Codon Optimization   
Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria
Authors: Belen Sotomayor, Thomas C Donahue, Sai Pooja Mahajan, May N Taw, Sophia W Hulbert, Erik J Bidstrup, D Natasha Owitipana, Alexandra Pang, Xu Yang, Souvik Ghosal, Christopher A Alabi, Parastoo Azadi, Jeffrey J Gray, Michael C Jewett, Lai-Xi Wang, Matthew P DeLisa
Journal: Nature Communications
PubMed ID: 40610439
Doi: 10.1038/s41467-025-61440-7
Products & Services: Peptide Synthesis   
Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2
Authors: Qian Wang, Yicheng Guo, Ryan G Casner, Jian Yu, Manoj S Nair, Jerren Ho, Eswar R Reddem, Ian A Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D Ho
Journal: Nature Communications
PubMed ID: 40615407
Doi: 10.1038/s41467-025-61472-z
Products & Services: Gene Synthesis   
Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses
Authors: Tobias Plowman, Tom Hofland, Callum Hall, Rachael Thompson, Judith Pape, Kevin W Ng, Laura Doglio, George Kassiotis
Journal: SCIENCE ADVANCES
PubMed ID: 40614216
Doi: 10.1126/sciimmunol.adr1105
Products & Services: Gene Synthesis   
Engineering precision zebrafish alleles of human disease
Authors: Holly R. Thomas; Bradley K. Yoder; Matthew S. Alexander; John M. Parant
Journal: biorxiv
PubMed ID: 40475461
Doi: 10.1101/2025.05.18.654701
Products & Services: Molecular Biology Reagents   
Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter -derived cephalosporinase-33 (ADC-33), a class C -lactamase present in carbapenem-resistant Acinetobacter baumannii (CR Ab )
Authors: Rachel A. Powers; Bradley J. Wallar; Hannah R. Jarvis; Zoe X. Ziegler; Cynthia M. June; Christopher R. Bethel; Andrea M. Hujer; Magdalena A. Taracila; Susan D. Rudin; Kristine M. Hujer; Fabio Prati; Emilia Caselli; Robert A. Bonomo
Journal: MBio
PubMed ID: 40377322
Doi: 10.1128/mbio.00287-25
The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM
Authors: Emil Gustavsson; Kay Gr newald; Per Elias; B Martin H llberg
Journal: Nucleic Acids Research
PubMed ID: 41125242
Doi: 10.1093/nar/gkaf1029
The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM
Authors: Emil Gustavsson; Kay Gr newald; Per Elias; B Martin H llberg
Journal: Nucleic Acids Research
PubMed ID: 41125242
Doi: 10.1093/nar/gkaf1029
Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis
Authors: Austin Tedman; Muskan Goel; Sohan Shah; Mathew K. Howard; Laura M. Chamness; Antonio Bonifasi; Ismalia Adams; Jacklyn M. Gallagher; Wesley D. Penn; Katarina Nemec; Eli F. McDonald; Brianna N. Corman; J. Paul Robinson; Carol Beth Post; Patricia L. Clark; M. Madan Babu; Aashish Manglik; Charles P. Kuntz; Willow Coyote-Maestas; Jonathan P. Schlebach
Journal: biorxiv
PubMed ID: 41000614
Doi: 10.1101/2025.09.19.677468
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