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Mechanism and spectrum of inhibition of a 4´-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses

Authors: Calvin J Gordon, Simon M Walker, Egor P Tchesnokov, Dana Kocincova, Jared Pitts, Dustin S Siegel, Jason K Perry, Joy Y Feng, John P Bilello, Matthias Götte

Journal: J Biol Chem

PubMed ID: 38945449

Doi: 10.1016/j.jbc.2024.107514

Products & Services: Molecular Biology Reagents

Broadly Applicable Bispecific Linker Approach to Noncovalently Target Therapeutic Nanoparticles to Tumor Cells Expressing Carcinoembryonic Antigen

Authors: Ann Fernando, Amanda Sparkes, Esther I Matus, Ayushi Patel, F Stuart Foster, David Goertz, Peter Lee, Jean Gariépy

Journal: ACS Pharmacol Transl Sci

PubMed ID: 38898951

Doi: 10.1021/acsptsci.4c00140

Products & Services: Catalog Peptides

Unraveling the Roles of Neuropeptides in the Chemosensation of the Root-Knot Nematode

Authors: Chenmi Mo, Lei Zhang

Journal: Int J Mol Sci

PubMed ID: 38928010

Doi: 10.3390/ijms25126300

Products & Services: Catalog Peptides

Cathepsins L and B target HIF1α for oxygen-independent proteolytic cleavage

Authors: Sarah Stuart, Daniel Tarade, Michael Ohh

Journal: Sci Rep

PubMed ID: 38926538

Doi: 10.1038/s41598-024-65537-9

Products & Services: Custom Vector Construction

Functional surface expression of immunoglobulin cleavage systems in a candidate Mycoplasma vaccine chassis

Authors: Sergi Torres-Puig, Silvia Crespo-Pomar, Hatice Akarsu, Thatcha Yimthin, Valentina Cippà, Thomas Démoulins, Horst Posthaus, Nicolas Ruggli, Peter Kuhnert, Fabien Labroussaa, Jörg Jores

Journal: Commun Biol

PubMed ID: 38942984

Doi: 10.1038/s42003-024-06497-8

Products & Services: Gene Synthesis

A chimeric membrane enzyme and an engineered whole-cell biocatalyst for efficient 1-alkene production

Authors: Tabish Iqbal, Subhashini Murugan, Debasis Das

Journal: Sci Adv

PubMed ID: 38924395

Doi: 10.1126/sciadv.adl2492

Products & Services: Protein and Antibody Isolation

A Plasmodium apicoplast-targeted unique exonuclease/FEN exhibits interspecies functional differences attributable to an insertion that alters DNA-binding

Authors: Tribeni Chatterjee, Anupama Tiwari, Ritika Gupta, Himadri Shukla, Aastha Varshney, Satish Mishra, Saman Habib

Journal: Nucleic Acids Res

PubMed ID: 38888125

Doi: 10.1093/nar/gkae512

Products & Services: Gene Synthesis

Optimization of dilution rate and mixed carbon feed for continuous production of recombinant plant sucrose:sucrose 1-fructosyltransferase in Komagataella phaffii

Authors: Avijeet S Jaswal, Ravikrishnan Elangovan, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 38904715

Doi: 10.1007/s00449-024-03045-w

Products & Services: PCR Cloning and Subcloning

CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels

Authors: Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xingxu Huang, Kui Li, Xinjie Wang, Fuling Zhou

Journal: Nat Commun

PubMed ID: 38866774

Doi: 10.1038/s41467-024-49414-7

Products & Services: Gene Synthesis

Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria

Authors: Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten

Journal: Nat Commun

PubMed ID: 38866748

Doi: 10.1038/s41467-024-49103-5

Products & Services: Recombinant Proteins