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页码: 138/5357 每页显示数量
Active- and Allosteric-Site Cyclic Peptide Inhibitors of Secreted M. tuberculosis Chorismate Mutase
Authors: Renier H P van Neer, Patricia K Dranchak, Mahesh Aitha, Lijun Liu, Emma K Carlson, Isabella E Jacobsen, Kevin Battaile, Yuhong Fang, Dingyin Tao, Ganesha Rai, Janak Padia, Scott Lovell, Hiroaki Suga, James Inglese
Journal: ACS Infectious Diseases
PubMed ID: 39903128
Doi: 10.1021/acsinfecdis.4c00798
Products & Services: Peptide Synthesis   Plasmid DNA Preparation   
Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody
Authors: Wen Peng, Gen Wan, Sufang Cheng, Guyue Li, Liling Liu, Juan Chen, Pei Liu, Xiaoquan Guo, Xiaona Gao, Gaofeng Cai, Zhanhong Zheng, Ping Liu
Journal: Int J Biol Macromol
PubMed ID: 39798767
Doi: doi.org/10.1016/j.ijbiomac.2025.139741
Products & Services: Protein Electrophoresis and Western   
A coronavirus assembly inhibitor that targets the viral membrane protein
Authors: Manon Laporte; Dirk Jochmans; Doroth e Bardiot; Lowiese Desmarets; Oliver J. Debski-Antoniak; Giulia Mizzon; Rana Abdelnabi; Pieter Leyssen; Winston Chiu; Zhikuan Zhang; Norimichi Nomura; Sandro Boland; Umeharu Ohto; Yannick Stahl; Jurgen Wuyts; Steven De Jonghe; Annelies Stevaert; Martijn J. van Hemert; Brenda W. Bontes; Patrick Wanningen; G. J. Mirjam Groenewold; Aneta Zegar; Katarzyna Owczarek; Sanjata Joshi; Mohamed Koukni; Philippe Arzel; Hugo Klaassen; Jean-Christophe Vanherck; Ilse Vandecaetsbeek; Niels Cremers; Kim Donckers; Thibault Francken; Tina Van Buyten; Jasper Rymenants; Joost Schepers; Krzysztof Pyrc; Rolf Hilgenfeld; Jean Dubuisson; Berend-Jan Bosch; Frank Van Kuppeveld; Cecilia Eydoux; Etienne Decroly; Bruno Canard; Lieve Naesens; Birgit Weynand; Eric J. Snijder; Sandrine Belouzard; Toshiyuki Shimizu; Ralf Bartenschlager; Daniel L. Hurdiss; Arnaud Marchand; Patrick Chaltin; Johan Neyts
Journal: Nature
PubMed ID: 40140569
Doi: 10.1038/s41586-025-08773-x
A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice
Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino
Journal: Vaccines
PubMed ID: 40432154
Doi: 10.3390/vaccines13050545
A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice
Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino
Journal: Vaccines
PubMed ID: 40432154
Doi: 10.3390/vaccines13050545
De novo design of a two-step approach targeting Claudin-6 for enhanced drug delivery to solid tumors
Authors: Jiayao Yan; Liqing Zhong; Xiaotong Chen; Lin Li; Fangcen Liu; Lei Lei; Mengchao An; Xiao Wei; Ying Wang; Tianran Chen; Jingyi Guo; Jie Shao; Xiaoxiao Yu; Yingjie Zhao; Rutian Li; Qin Liu; Baorui Liu
Journal: Journal of translational medicine
PubMed ID: 41267074
Doi: 10.1186/s12967-025-07316-2
De novo design of a two-step approach targeting Claudin-6 for enhanced drug delivery to solid tumors
Authors: Jiayao Yan; Liqing Zhong; Xiaotong Chen; Lin Li; Fangcen Liu; Lei Lei; Mengchao An; Xiao Wei; Ying Wang; Tianran Chen; Jingyi Guo; Jie Shao; Xiaoxiao Yu; Yingjie Zhao; Rutian Li; Qin Liu; Baorui Liu
Journal: Journal of translational medicine
PubMed ID: 41267074
Doi: 10.1186/s12967-025-07316-2
Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus
Authors: Yansi Xian, Bin Liu, Tao Shen, Lin Yang, Rui Peng, Hongdou Shen, Xueying An, Yutian Wang, Yu Ben, Qing Jiang, Baosheng Guo
Journal: Bone Res
PubMed ID: 40025004
Doi: 10.1038/s41413-024-00399-5
Products & Services: Protein and Antibody Isolation   
Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs
Authors: Jibin Cui , Qingyun Zheng , Yicheng Weng , Xiaoguo Zhai , Zhen Su , Yunxiang Du , Xiaoxiong Wei , Yuanyuan Yu , Qian Qu , Man Pan
Journal: Analytical Chemistry
PubMed ID: 40000409
Doi: doi.org/10.1002/anie.202501488
Products & Services: Codon Optimization   Gene Synthesis   
Rational Design Assisted by Evolutionary Engineering Allows (De)Construction and Optimization of Complex Phenotypes in Pseudomonas putida KT2440
Authors: Blas Blázquez, Juan Nogales
Journal: Microbial biotechnology
PubMed ID: 40126873
Doi: 10.1111/1751-7915.70132
Products & Services: Gene Synthesis   
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