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Defining essential charged residues in fibril formation of a lysosomal derived N-terminal α-synuclein truncation

Authors: Ryan P McGlinchey, Sashary Ramos, Emilios K Dimitriadis, C Blake Wilson, Jennifer C Lee

Journal: Nature Communications

PubMed ID: 40268916

Doi: 10.1038/s41467-025-58899-9

Products & Services: Gene Synthesis

Unexpected enzymatic function of an ancient nucleic acid-binding fold

Authors: Rylan R Watkins, Stella Bockelman, Anna Vradi, Kaylee Grabarkewitz, Alexa Pyun, Josephine Stark, Vicki H Wysocki, Juan D Alfonzo, Karin Musier-Forsyth

Journal: Nucleic Acids Research

PubMed ID: 40274265

Doi: 10.1093/nar/gkaf328

Products & Services: Gene Synthesis

Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface

Authors: Lukas Broich, Hannah Wullenkord, Maria Kaukab Osman, Yang Fu, Mathias Müsken, Peter Reuther, Mark Brönstrup & Christian Sieben

Journal: Nature Communications

PubMed ID: 40280912

Doi: 10.1038/s41467-025-58935-8

Products & Services: Custom Vector Construction

Using Regular Porous Membrane-Based Blood−Brain Barrier Model to Screen Brain-Targeted Drugs with Nanochannel Electrochemistry

Authors: Yafeng Wu，Zixuan Chen，Fengxiang Chen，Juan Su，Jianyu Han，Songqin Liu

Journal: Anal Chem

PubMed ID: 40183921

Doi: 10.1021/acs.analchem.5c00365

Products & Services: Peptide Synthesis

Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus

Authors: Haining Li , Luyuan Shao , Zhe Liu , Qi Liu , Ye Xiang

Journal: Nat Commun

PubMed ID: 40301360

Doi: 10.1038/s41467-025-59301-4

Products & Services: Protein and Antibody Isolation

Self-oxygenating nanoplatform integrating CRISPR/Cas9 gene editing and immune activation for highly efficient photodynamic therapy

Authors: Shi-Cheng Tian, Xun-Huan Song, Ke-Ke Feng, Cheng-Lei Li, Yi-Fan Tu, Yong-Shan Hu, Jing-Wei Shao

Journal: Journal of colloid and interface science

PubMed ID: 40262200

Doi: 10.1016/j.jcis.2025.137632

Products & Services: Synthetic Guide RNA

Molecular determinants for the association of human hormone-sensitive lipase with lipid droplets

Authors: Han Peng, Qikui Xu, Ting Zhang, Jiakai Zhu, Jinheng Pan, Xiaoyu Guan, Shan Feng, Jianping Wu, Qi Hu

Journal: nature COMMUNICATION

PubMed ID: 40221426

Doi: 10.1038/s41467-025-58887-z

Products & Services: Protein and Antibody Isolation

Inhibition of CHI3L1 attenuates excessive autophagy in intestinal epithelial cells to reduce the severity of necrotizing enterocolitis

Authors: Yihui Li, Wenqiang Sun, Xinyun Jin, Huiwen Li, Xue Liu, Jingtao Bian, Xueping Zhu

Journal: Cell Death Discov

PubMed ID: 40188090

Doi: 10.1038/s41420-025-02443-7.

Products & Services: Protein and Antibody Isolation

Nanosized Shikonin Disrupts Tumor-cell Mismatch Repair and Synergizes with Manganese to Sensitize Squamous Carcinoma to Immunotherapy

Authors: Shan Yu, Jingyuan Li, Jie Zhang, Guozhong Zeng, Bin Zeng, Shuyuan Song, Zhentao Lao, Haolin Chen, Zhenfu Wen, Zeyu Yang, Xiang Li, Kan Li, Le Yang, Hong Liu, Lixin Liu, Guiqing Liao, Yongming Chen, Yujie Liang

Journal: ACS Nano

PubMed ID: 40190094

Doi: 10.1021/acsnano.4c17090.

Products & Services: Protein and Antibody Isolation

Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel

Authors: Young-Woo Nam, Dohyun Im, Ana Santa Cruz Garcia, Marios L Tringides, Hai Minh Nguyen, Yan Liu, Razan Orfali, Alena Ramanishka, Grigore Pintilie, Chih-Chia Su, Meng Cui, Diomedes E Logothetis, Edward W Yu, Heike Wulff, K George Chandy, Miao Zhang

Journal: Nat Commun

PubMed ID: 40246884

Doi: /10.1038/s41467-025-59061-1

Products & Services: Gene Synthesis