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Functional implications of hexameric dynamics in SARS-CoV-2 Nsp15

Authors: Manashi Sonowal, Gihan Ketawala, Nirupa Nagaratnam, Dhenugen Logeswaran, Shibom Basu, Daniele de Sanctis, Julien Orlans, Samuel L Rose, Rebecca J Jernigan, Hao Hu, Jose Domingo Meza Aguilar, Madurangi E Ranaweera, Michele A Zacks, Julian J-L Chen, Debra T Hansen, Lynn G Schrag, Raimund Fromme, Sabine Botha, Petra Fromme

Journal: Protein Science

PubMed ID: 40411374

Doi: 10.1002/pro.70115

Products & Services: Plasmids for SARS-CoV-2 Detection and Research Custom DNA/RNA Oligos

Electrochemical sensor toolkit for simultaneous glutamate detection at edge of cleft and peri-soma

Authors: Jie Liu, Yuandong Liu, Dongmin Yin, Yang Tian

Journal: Cell chemical biology

PubMed ID: 40466640

Doi: 10.1016/j.chembiol.2025.05.002

Products & Services: Gene Synthesis

Direct Observation of Secondary Nucleation in Huntingtin Amyloid Formation by High-Speed Atomic Force Microscopy

Authors: Chris van Ewijk, Greeshma Jain, Yari K Knelissen, Sourav Maity, Patrick C A van der Wel, Wouter H Roos

Journal: J Am Chem Soc

PubMed ID: 40505012

Doi: 10.1021/jacs.5c05571

Products & Services: Plasmid DNA Preparation

Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis

Authors: Manuel L. Merz; Veronika M. Shoba; Rajaiah Pergu; Zachary C. Severance; Dhanushka N. P. Munkanatta Godage; Arghya Deb; Hui Si Kwok; Prashant Singh; Sameek Singh; Jonathan B. Allen; Wenzhi Tian; Pallavi M. Gosavi; Santosh K. Chaudhary; Viktoriya Anokhina; Ellen L. Weisberg; N. Connor Payne; Yao He; Reilly Osadchey; Mrinal Shekhar; Ralph Mazitschek; Matthew G. Rees; Jennifer A. Roth; Qiang Cui; James D. Griffin; Brian B. Liau; Amit Choudhary

Journal: biorxiv

PubMed ID: 40661463

Doi: 10.1101/2025.06.13.659082

Products & Services: PCR Cloning and Subcloning

Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis

Journal: biorxiv

PubMed ID: 40661463

Doi: 10.1101/2025.06.13.659082

Products & Services: PCR Cloning and Subcloning

Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes

Authors: Jiangming Zhong; Ling Liang; Nan Zhao; Jing Wang; Peng Shu

Journal: Frontiers in pharmacology

PubMed ID: 40343007

Doi: 10.3389/fphar.2025.1562244

Products & Services: Protein Electrophoresis and Western

H19 influenza A virus exhibits species-specific MHC-II receptor usage

Authors: Umut Karakus; Ignacio Mena; Jithesh Kottur; Sara S. El Zahed; Roc o Seoane; Soner Yildiz; Leanne Chen; Magdalena Plancarte; LeAnn Lindsay; Rebecca Halpin; Timothy B Stockwell; David E. Wentworth; Geert-Jan Boons; Florian Krammer; Silke Stertz; Walter Boyce; Robert P de Vries; Aneel K Aggarwal; Adolfo Garc a-Sastre

Journal: Cell Host & Microbe

PubMed ID: 38889725

Doi: 10.1016/j.chom.2024.05.018

Doublet decoding of tRNASer3 demonstrates plasticity of ribosomal decoding center

Authors: Shruthi Krishnaswamy, Shirin Akbar, Daniel S D Larsson, Yang Chen, Maria Selmer

Journal: Nature Communications

PubMed ID: 40571681

Doi: 10.1101/2024.12.14.628468

Products & Services: Custom DNA/RNA Oligos

Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses

Authors: Kong Yen Liew, Yaju Wang, Sneha Sree Mullapudi, Dinah Binte Aziz, Wenjie Fan, Min Luo, Paul Anantharajah Tambyah, Yee-Joo Tan

Journal: Viruses

PubMed ID: 40733504

Doi: 10.3390/v17070886

Products & Services: Gene Synthesis Codon Optimization PCR Cloning and Subcloning

Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain

Authors: Guillaume Mas , Sebastian Hiller

Journal: Nature Communications

PubMed ID: 40449998

Doi: 10.1038/s41467-025-60343-x

Products & Services: Gene Synthesis