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页码: 91/5357 每页显示数量

Engineering precision zebrafish alleles of human disease

Authors: Holly R. Thomas; Bradley K. Yoder; Matthew S. Alexander; John M. Parant

Journal: biorxiv

PubMed ID: 40475461

Doi: 10.1101/2025.05.18.654701

Products & Services: Molecular Biology Reagents

Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter -derived cephalosporinase-33 (ADC-33), a class C -lactamase present in carbapenem-resistant Acinetobacter baumannii (CR Ab )

Authors: Rachel A. Powers; Bradley J. Wallar; Hannah R. Jarvis; Zoe X. Ziegler; Cynthia M. June; Christopher R. Bethel; Andrea M. Hujer; Magdalena A. Taracila; Susan D. Rudin; Kristine M. Hujer; Fabio Prati; Emilia Caselli; Robert A. Bonomo

Journal: MBio

PubMed ID: 40377322

Doi: 10.1128/mbio.00287-25

The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM

Authors: Emil Gustavsson; Kay Gr newald; Per Elias; B Martin H llberg

Journal: Nucleic Acids Research

PubMed ID: 41125242

Doi: 10.1093/nar/gkaf1029

The herpes simplex origin-binding protein: mechanisms for sequence-specific DNA binding and dimerization revealed by Cryo-EM

Authors: Emil Gustavsson; Kay Gr newald; Per Elias; B Martin H llberg

Journal: Nucleic Acids Research

PubMed ID: 41125242

Doi: 10.1093/nar/gkaf1029

Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis

Authors: Austin Tedman; Muskan Goel; Sohan Shah; Mathew K. Howard; Laura M. Chamness; Antonio Bonifasi; Ismalia Adams; Jacklyn M. Gallagher; Wesley D. Penn; Katarina Nemec; Eli F. McDonald; Brianna N. Corman; J. Paul Robinson; Carol Beth Post; Patricia L. Clark; M. Madan Babu; Aashish Manglik; Charles P. Kuntz; Willow Coyote-Maestas; Jonathan P. Schlebach

Journal: biorxiv

PubMed ID: 41000614

Doi: 10.1101/2025.09.19.677468

Polyketide synthase-derived sphingolipids mediate microbiota protection against a bacterial pathogen in C. elegans

Authors: Lena Peters, Moritz Drechsler, Michael A Herrera, Jing Liu, Barbara Pees, Johanna Jarstorff, Anna Czerwinski, Francesca Lubbock, Georgia Angelidou, Liesa Salzer, Karlis Arturs Moors, Nicole Paczia, Yi-Ming Shi, Hinrich Schulenburg, Christoph Kaleta, Michael Witting, Manuel Liebeke, Dominic J Campopiano, Helge B Bode, Katja Dierking

Journal: Nature Communications

PubMed ID: 40461452

Doi: 10.1038/s41467-025-60234-1

Products & Services: Gene Synthesis

Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response

Authors: Kenta Matsuda, Mitra Harrison, Eleanor Wettstein, Jessica Pederson, Alyssa A Pullano, Lyuba Bolkhovitinov, Breanna Kim, Isabel Steinberg, Trevor Griesman, Sarah Stuccio, Daniel Rogan, Andy Patamawenu, Tulley Shofner, Nathaniel E Wright, Jonathan D Webber, Freya Van't Veer, Rachel Roenicke, Emma Koory, Peyton M Roeder, Ellison Ober, Benjamin Leach, Yaroslav Tsybovsky, Tyler Stephens, Ivan Del Moral-Sanchez, Ilja Bontjer, Lori W McGinnes-Cullen, Eric Chu, Jason Liang, Jonathan L Torres, Ryan N Lin, Andy S Tran, Gabrielle Dziubla, Leonid Serebryannyy, Sandeep Narpala, Bob Lin, Mike Castro, Gabriel Ozorowski, Andrew B Ward, Rogier W Sanders, Peter D Kwong, Javier Guenaga, Richard Wyatt, Trudy Morrison, Mark Connors

Journal: Nature Communications

PubMed ID: 40461490

Doi: 10.1038/s41467-025-60481-2

Products & Services: Recombinant Proteins

H3.3 deposition counteracts the replication-dependent enrichment of H3.1 at chromocenters in embryonic stem cells

Authors: S Arfè, T Karagyozova, A Forest, D Bingham, H Hmidan, D Mazaud, M Garnier, P Le Baccon, E Meshorer, J-P Quivy, G Almouzni

Journal: Nature Communications

PubMed ID: 40461574

Doi: 10.1038/s41467-025-60430-z

Products & Services: Mutagenesis Services

Structural and molecular mechanisms of an Ro60 homolog from a Thermus bacteriophage

Authors: Zetao Hu, Zhaohui Jin, Lulu Guo, Ling Zeng, Xuanjia Dong, Lin Jiang, Wenting Dai, Jinbiao Ma, Ying Huang

Journal: Nucleic Acids Research

PubMed ID: 40464688

Doi: 10.1093/nar/gkaf470

A post-assembly conformational change makes the SARS-CoV-2 polymerase elongation-competent

Authors: Misha Klein, Arnab Das, Subhas C Bera, Thomas K Anderson, Dana Kocincova, Hery W Lee, Bing Wang, Flavia S Papini, John C Marecki, Jamie J Arnold, Craig E Cameron, Kevin D Raney, Irina Artsimovitch, Mathias Götte, Robert N Kirchdoerfer, Martin Depken, David Dulin

Journal: Nucleic Acids Research

PubMed ID: 40464687

Doi: 10.1093/nar/gkaf450

Products & Services: PCR Cloning and Subcloning