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14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin

Authors: Vikram Bhatia; Saeid Maghsoudi; Martha Hinton; Anjali Y. Bhagirath; Nisha Singh; Appalaraju Jaggupilli; Prashen Chelikani; Shyamala Dakshinamurti

Journal: Biology

PubMed ID: 37106773

Doi: 10.3390/biology12040572

Products & Services: Gene Synthesis

Functional Analysis of the Yeast Counterpart to the Human GCN2 p.Glu738_Asp739insArgArg Variant

Authors: Anja H Schiemann, Makhdoom Sarwar, Evelyn Sattlegger

Journal: microPublication biology

PubMed ID: 40880988

Doi: 10.17912/micropub.biology.001767

Products & Services: Mutagenesis Services

Structural basis for small molecule binding to the SARS-CoV-2 nsp10-nsp14 ExoN complex

Authors: Frank Kozielski, Suzanne Zoë Fisher, Shumeng Ma, Fatma Al Busaidi, Ewa Krupinska, Maria Nyblom, Céleste Sele, Heather McDuffie Sullivan, Tobias Krojer, Wolfgang Knecht

Journal: Nucleic Acids Research

PubMed ID: 40794865

Doi: 10.1093/nar/gkaf753

Products & Services: Codon Optimization

Anti-CV2/CRMP5 autoantibodies as drivers of sensory neuron excitability and pain in rats

Authors: Laurent Martin, Harrison J Stratton, Lyuba Y Salih, Nicolas LA Dumaire, Kimberly Gomez, Le Duy Do, Santiago Loya-Lopez, Cheng Tang, Aida Calderon-Rivera, Dongzhi Ran, Venkatrao Nunna, Shreya S Bellampalli, Liberty François-Moutal, Shizhen Luo, Frank Porreca, Mohab Ibrahim, Véronique Rogemond, Jérôme Honnorat, Rajesh Khanna, Aubin Moutal

Journal: Nature Communications

PubMed ID: 40775229

Doi: 10.1038/s41467-025-62380-y.

Products & Services: Peptide Synthesis

Functional and epitope specific monoclonal antibody discovery directly from immune sera using cryo-EM

Authors: James A Ferguson, Sai Sundar Rajan Raghavan, Garazi Peña Alzua, Disha Bhavsar, Jiachen Huang, Alesandra J Rodriguez, Jonathan L Torres, Maria Bottermann, Julianna Han, Florian Krammer, Facundo D Batista, Andrew B Ward

Journal: SCIENCE ADVANCES

PubMed ID: 40815640

Doi: 10.1126/sciadv.adv8257

Products & Services: Recombinant Antibody Expression

Internal ribosome entry sites enhance translation in trans in antisense non-coding SINEUP and circular RNAs

Authors: Sabrina D'Agostino, Abraham Tettey-Matey, Massimiliano Volpe, Bianca Pierattini, Mattia D'Agostino, Denisa Smělá, Federico Ansaloni, Laura Broglia, Pierre Lau, Omar Peruzzo, Clarissa Braccia, Andrea Armirotti, Margherita Scarpato, Devid Damiani, Gloria Ros, Valerio Di Carlo, Federica Maniscalco, Elias Bechara, Gian Gaetano Tartaglia, Piero Carninci, Claudio Santoro, Francesca Persichetti, Luca Pandolfini, Angelita Simonetti, Stefano Espinoza, Silvia Zucchelli, Remo Sanges, Carlotta Bon, Stefano Gustincich

Journal: Nucleic Acids Research

PubMed ID: 40823812

Doi: 10.1093/nar/gkaf788

Products & Services: Custom Vector Construction

Structural insights into Type II-D Cas9 and its robust cleavage activity

Authors: Kangkang Wang, Jiuyu Wang, Xiaoqi Yang, Wei Sun, Gang Sheng, Yanli Wang

Journal: Nature Communications

PubMed ID: 40790018

Doi: 10.1038/s41467-025-62128-8.

Products & Services: Codon Optimization

Expanding the cytokine receptor alphabet reprograms T cells into diverse states

Authors: Yang Zhao, Masato Ogishi, Aastha Pal, Leon L. Su, Pingdong Tao, Hua Jiang, Grayson E. Rodriguez, Xiaojing Chen, Qinli Sun, Lea Wenting Rysavy, Sam Limsuwannarot, Deepa Waghray, Anusha Kalbasi, K. Christopher Garcia

Journal: Nature

PubMed ID: 40804519

Doi: 10.1038/s41586-025-09393-1.

Products & Services: Peptide Synthesis