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Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation

Authors: Zixuan Mei, Kamuran Yilamu, Weiyu Ni, Panyang Shen, Nan Pan, Huasen Chen, Yingfeng Su, Lei Guo, Qunan Sun, Zhaomei Li, Dongdong Huang, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen

Journal: nature COMMUNICATION

PubMed ID: 40425566

Doi: 10.1038/s41467-025-60037-4

Products & Services: Catalog Antibodies Protein and Antibody Isolation

MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex

Authors: Xinyue Wu , Xin Gong , Tian Xie

Journal: nature COMMUNICATION

PubMed ID: 40442105

Doi: doi.org/10.1038/s41467-025-60423-y

Products & Services: Protein and Antibody Isolation

DNA-Engineered Modular Nanovaccines Featuring Precise Topology for Enhanced Immunogenicity

Authors: Yanfei Qu, Dawei Wang, Yunlong Zhang, Fengyun Shen, Binghui Xia, Qin Xu, Qisheng Wang, Huating Kong, Ying Zhu, Lihua Wang, Itamar Willner, Xiurong Yang, Chunhai Fan, Lele Sun

Journal: ADVANCED MATERIALS

PubMed ID: 40371439

Doi: 10.1002/adma.202500577

Products & Services: Protein and Antibody Reagents

Deep Proteomic Profiling of the Intra-Golgi Trafficking Intermediates

Authors: Farhana Taher Sumya , Walter S Aragon-Ramirez , Vladimir V Lupashin

Journal: Molecular biology of the cell

PubMed ID: 40397568

Doi: 10.1091/mbc.E24-12-0556

Products & Services: Gene Synthesis

Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease

Authors: Peifen Lu, Hongxiu Yuan, Gang Wang, Yixi Dong, Runyu Zhao, Jia Man, Jianwei Jiao, Zhaoyin Wang, Jin Jiao

Journal: Theranostics

Doi: 10.7150/thno.111583

Products & Services: Protein and Antibody Isolation

Engineering galactose oxidase for biocatalytic synthesis of 2-(furan-2-yl)-2-oxoacetic acid, a critical precursor of cefuroxime

Authors: Tong Zhang, Hao Wei, Yunju Zhang, Tengteng Qi, Kehao Yuan, Bin Wang, Ziyan Zhang, Liangqing Chen, Qinyuan Ma, Xiuzhen Gao

Journal: Journal Pre-proof

Doi: 10.1016/j.gresc.2025.05.010

Cnidaria XIAP activates caspase-mediated cell death

Authors: Yuan Chen, Meng Wu, Zihao Yuan, Qingyue Wang, Hang Xu, Li Sun

Journal: International Journal of Biological Macromolecules

PubMed ID: 40288723

Doi: doi.org/10.1016/j.ijbiomac.2025.143427

Products & Services: Protein and Antibody Isolation

A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase mediated catalysis

Authors: Pallavi Singh; Jae-Yeon Choi; Weiwei Wang; Tukiet T. Lam; Philip Lechner; Christopher D. Vanderwal; Sovitj Pou; Aaron Nilsen; Choukri Ben Mamoun

Journal: The Journal of Biological Chemistry

PubMed ID: 39342998

Doi: 10.1016/j.jbc.2024.107832

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

Authors: Xujie Zhang; Lin Sun; Megan E. Meuser; Waleed A. Zalloum; Shujing Xu; Tianguang Huang; Srinivasulu Cherukupalli; Xiangyi Jiang; Xiao Ding; Yucen Tao; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Alexej Dick; Simon Cocklin; Xinyong Liu; Peng Zhan

Journal: European Journal of Medicinal Chemistry

PubMed ID: 34592608

Doi: 10.1016/j.ejmech.2021.113848

Products & Services: Peptide Synthesis

CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters

Authors: Fadi Shehadeh; Biswajit Mishra; Raquel Ferrer-Espada; Anindya Basu; LewisOscar Felix; Charilaos Dellis; Narchonai Ganesan; Liyang Zhang; Andrew T. Martens; Youlian Goulev; Michael B. Sherman; Johan Paulsson; Mandar T. Naik; Paul P. Sotiriadis; Eleftherios Mylonakis

Journal: Nature Communications

PubMed ID: 41803147

Doi: 10.1038/s41467-026-70348-9

Products & Services: Peptide Synthesis