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The TMEM63B Channel Facilitates Intestinal Motility and Enhances Proliferation of Intestinal Stem Cells

Authors: Jing-Jing Tu , Yan-Yu Zang , Yun Stone Shi ,and Xiao-Yu Teng

Journal: Cells

Doi: doi.org/10.3390/cells13211784

Products & Services: Molecular Biology Reagents

5′-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response

Authors: Hanyong Jin , Ji-Hyun Yeom , Eunkyoung Shin , Yoonjie Ha , Haifeng Liu , Daeyoung Kim , Minju Joo , Yong-Hak Kim , Hak Kyun Kim , Minkyung Ryu, Hong-Man Kim , Jeongkyu Kim , Keun P Kim , Yoonsoo Hahn , Jeehyeon Bae , Kangseok Lee

Journal: Nature Communications

PubMed ID: 39468069

Doi: 10.1038/s41467-024-53624-4

Products & Services: Custom Vector Construction

Zinc oxide nanoparticles with catalase-like nanozyme activity and near-infrared light response: A combination of effective photodynamic therapy, autophagy, ferroptosis, and antitumor immunity

Authors: Jingru Wang , Man Liu , Jingwen Wang , Zhuoyue Li , Zhenhan Feng , Meiqi Xu , Hui Wang , Hui Li , Zhantao Li , Jianming Yu , Junwei Liu , Qingchao Wei , Shuang Zhang , Xuan Zhang

Journal: Acta Pharm Sin B

PubMed ID: 39525585

Doi: 10.1016/j.apsb.2024.07.002

Products & Services: Recombinant Proteins

Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O-Glycosylation

Authors: Amrita Khakurel , Irina Pokrovskaya , Vladimir V Lupashin

Journal: Traffic

PubMed ID: 39416116

Doi: 10.1111/tra.70003

Products & Services: Protein and Antibody Isolation Gene Synthesis

Target-based design of praziquantel analogs at cestode TRPM PZQ

Authors: Daniel J. Sprague; Sang-Kyu Park; Marc Kaethner; Claudia M. Rohr; Mina R. Ghobrial; D. Connor Barth; David Maillard; Thomas Spangenberg; Britta Lundstr m-Stadelmann; Jonathan S. Marchant

Journal: ACS Infectious Diseases

PubMed ID: 40754814

Doi: 10.1021/acsinfecdis.5c00449

Enhanced HIV SOSIP Envelope yields in plants through transient co-expression of peptidyl-prolyl isomerase B and calreticulin chaperones and ER targeting

Authors: Yvonne J. Rosenberg; Xiaoming Jiang; Jonathan P. Lees; Lori A. Urban; Lingjun Mao; Markus Sack

Journal: Scientific REPORTS

PubMed ID: 35705669

Doi: 10.1038/s41598-022-14075-3

Products & Services: Catalog Antibodies

Structure of Plasmodium vivax N -myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy

Authors: Alex Mendez; Cydni Bolling; Shane Taylor; Stanley Makumire; Bart Staker; Alexandra Reers; Brad Hammerson; Stephen J. Mayclin; Jan Abendroth; Donald D. Lorimer; Thomas E. Edwards; Edward W. Tate; Sandhya Subramanian; Andrew S. Bell; Peter J. Myler; Oluwatoyin A. Asojo; Graham Chakafana

Journal: Acta Crystallographica Section F: Structural Biology Communications

PubMed ID: 39655507

Doi: 10.1107/S2053230X24011348

Next-generation cell-penetrating antibodies for tumor targeting and RAD51 inhibition

Authors: Madison Rackear, Elias Quijano, Zaira Ianniello, Daniel A Colón-Ríos, Adam Krysztofiak, Rashed Abdullah, Yanfeng Liu, Faye A Rogers, Dale L Ludwig, Rohini Dwivedi, Franziska Bleichert, Peter M Glazer

Journal: Oncotarget

PubMed ID: 39352803

Doi: 10.18632/oncotarget.28651

Products & Services: Mammalian Expression Custom mRNA synthesis

Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists

Authors: Shristi Pawnikar; Brenda S Magenheimer; Keya Joshi; Ericka Nevarez-Munoz; Allan Haldane; Robin L Maser; Yinglong Miao; Qiang Cui; Shristi Pawnikar; Brenda Magenheimer; Keya Joshi; Ericka Nevarez-Munoz; Allan Haldane; Robin Maser; Yinglong Miao

Journal: Elife

PubMed ID: 39373641

Doi: 10.7554/eLife.95992

Products & Services: Peptide Synthesis

A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma

Authors: Xinhui Hui1†Muhammad Asad Farooq,&#x;Muhammad Asad Farooq1,2†Yiran ChenYiran Chen1Iqra Ajmal,Iqra Ajmal1,2Yaojun Ren,Yaojun Ren1,3Min XueMin Xue1Yuzhou JiYuzhou Ji1Bingtan DuBingtan Du1Shijia WuShijia Wu1Wenzheng Jiang*&#x;Wenzheng Jiang1*‡

Journal: Frontiers in Immunology

Doi: doi.org/10.3389/fimmu.2024.1462076

Products & Services: Nucleic Acid Purification