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页码: 166/5356 每页显示数量
The E3 Ubiquitin Ligase FBXO38 Maintains the Antitumor Function of Natural Killer Cells by Sustaining IL15R Signaling
Authors: Yongjing Shi , Xiaodong Zheng , Hui Peng , Chenqi Xu , Rui Sun , Zhigang Tian , Haoyu Sun , Xianwei Wang
Journal: Cancer Immunol Res
PubMed ID: 38990095
Doi: 10.1158/2326-6066.CIR-23-1061
Products & Services: Protein and Antibody Isolation   
Neddylation and Its Target Cullin 3 Are Essential for Adipocyte Differentiation
Authors: Hongyi Zhou , Vijay Patel , Robert Rice , Richard Lee , Ha Won Kim , Neal L Weintraub , Huabo Su , Weiqin Chen
Journal: Cells
PubMed ID: 39404417
Doi: 10.3390/cells13191654
Products & Services: CRISPR Libraries   
Activation of polycystin-1 signaling by binding of stalk-derived peptide agonists
Authors: Shristi Pawnikar; Brenda S Magenheimer; Keya Joshi; Ericka Nevarez-Munoz; Allan Haldane; Robin L Maser; Yinglong Miao; Qiang Cui; Shristi Pawnikar; Brenda Magenheimer; Keya Joshi; Ericka Nevarez-Munoz; Allan Haldane; Robin Maser; Yinglong Miao
Journal: Elife
PubMed ID: 39373641
Doi: 10.7554/eLife.95992
Products & Services: Peptide Synthesis   
Target-based design of praziquantel analogs at cestode TRPM PZQ
Authors: Daniel J. Sprague; Sang-Kyu Park; Marc Kaethner; Claudia M. Rohr; Mina R. Ghobrial; D. Connor Barth; David Maillard; Thomas Spangenberg; Britta Lundstr m-Stadelmann; Jonathan S. Marchant
Journal: ACS Infectious Diseases
PubMed ID: 40754814
Doi: 10.1021/acsinfecdis.5c00449
Target-based design of praziquantel analogs at cestode TRPM PZQ
Authors: Daniel J. Sprague; Sang-Kyu Park; Marc Kaethner; Claudia M. Rohr; Mina R. Ghobrial; D. Connor Barth; David Maillard; Thomas Spangenberg; Britta Lundstr m-Stadelmann; Jonathan S. Marchant
Journal: ACS Infectious Diseases
PubMed ID: 40754814
Doi: 10.1021/acsinfecdis.5c00449
Target-based design of praziquantel analogs at cestode TRPM PZQ
Authors: Daniel J. Sprague; Sang-Kyu Park; Marc Kaethner; Claudia M. Rohr; Mina R. Ghobrial; D. Connor Barth; David Maillard; Thomas Spangenberg; Britta Lundstr m-Stadelmann; Jonathan S. Marchant
Journal: ACS Infectious Diseases
PubMed ID: 40754814
Doi: 10.1021/acsinfecdis.5c00449
Structure of Plasmodium vivax N -myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy
Authors: Alex Mendez; Cydni Bolling; Shane Taylor; Stanley Makumire; Bart Staker; Alexandra Reers; Brad Hammerson; Stephen J. Mayclin; Jan Abendroth; Donald D. Lorimer; Thomas E. Edwards; Edward W. Tate; Sandhya Subramanian; Andrew S. Bell; Peter J. Myler; Oluwatoyin A. Asojo; Graham Chakafana
Journal: Acta Crystallographica Section F: Structural Biology Communications
PubMed ID: 39655507
Doi: 10.1107/S2053230X24011348
Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder
Authors: Percy S Agogo-Mawuli, Joseph Mendez, Emily A Oestreich, Dustin E Bosch, David P Siderovski
Journal: International Journal of Molecular Sciences
PubMed ID: 39518985
Doi: 10.3390/ijms252111431
Products & Services: Peptide Synthesis   Bacterial Expression   
Two riboswitch classes that share a common ligand-binding fold show major differences in the ability to accommodate mutations
Authors: Yoshita Srivastava , Olayinka Akinyemi , Tiana C Rohe , Elizabeth M Pritchett , Cameron D Baker , Akshara Sharma , Jermaine L Jenkins , David H Mathews , Joseph E Wedekind
Journal: Nucleic Acids Research
PubMed ID: 39413212
Doi: 10.1093/nar/gkae886
Disrupting Intracellular Homeostasis by Copper-Based Nanoinducer with Multiple Enzyme-Mimicking Activities to Induce Disulfidptosis-Enhanced Pyroptosis for Tumor Immunotherapy
Authors: Xiao-Kang Jin , Shun-Kang Zhang , Shi-Man Zhang , Jun-Long Liang , Xiao Yan , Yan-Tong Lin , Ran Meng , Zi-Han Xu , Chuan-Jun Liu , Xian-Zheng Zhang
Journal: ADVANCED MATERIALS
PubMed ID: 39468892
Doi: 10.1002/adma.202410957
Products & Services: Recombinant Proteins   
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