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Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Authors: Cheng-Bao Ma, Chen Liu, Young-Jun Park, Jingjing Tang, Jing Chen, Qing Xiong, Jimin Lee, Cameron Stewart, Daniel Asarnow, Jack Brown, M Alejandra Tortorici, Xiao Yang, Ye-Hui Sun, Yuan-Mei Chen, Xiao Yu, Jun-Yu Si, Peng Liu, Fei Tong, Mei-Ling Huang, Jing Li, Zheng-Li Shi, Zengqin Deng, David Veesler, Huan Yan

Journal: Cell

PubMed ID: 39922191

Doi: 10.1016/j.cell.2024.12.031

Products & Services: Codon Optimization

Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses

Authors: Young-Jun Park, Chen Liu, Jimin Lee, Jack T Brown, Cheng-Bao Ma, Peng Liu, Risako Gen, Qing Xiong, Samantha K Zepeda, Cameron Stewart, Amin Addetia, Caroline J Craig, M Alejandra Tortorici, Abeer N Alshukairi, Tyler N Starr, Huan Yan, David Veesler

Journal: Cell

PubMed ID: 39922192

Doi: 10.1016/j.cell.2024.12.032

Products & Services: Codon Optimization

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling

Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Journal: Nature Communications

PubMed ID: 39920161

Doi: 10.1038/s41467-025-56713-0

Products & Services: Peptide Synthesis

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350

Authors: M Gordon Joyce, Wei Bu, Wei-Hung Chen, Rebecca A Gillespie, Sarah F Andrews, Adam K Wheatley, Yaroslav Tsybovsky, Jaime L Jensen, Tyler Stephens, Madhu Prabhakaran, Brian E Fisher, Sandeep R Narpala, Meghna Bagchi, Adrian B McDermott, Gary J Nabel, Peter D Kwong, John R Mascola, Jeffrey I Cohen, Masaru Kanekiyo

Journal: Immunity

PubMed ID: 39909035

Doi: 10.1016/j.immuni.2025.01.010

Products & Services: Recombinant Antibody Expression

Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

Authors: Prakash Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra Ford, Francesc Xavier Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

Journal: Nature Communications

PubMed ID: 39948104

Doi: 10.1038/s41467-025-56902-x

Products & Services: Codon Optimization

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

The CXCL8/MAPK/hnRNP-K axis enables susceptibility to infection by EV-D68, rhinovirus, and influenza virus in vitro

Authors: Qingran Yang, Haoran Guo, Huili Li, Zhaoxue Li, Fushun Ni, Zhongmei Wen, Kai Liu, Huihui Kong, Wei Wei

Journal: Nature Communications

PubMed ID: 39962077

Doi: 10.1038/s41467-025-57094-0

Products & Services: Catalog Antibodies

Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

Authors: Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M Szewczyk, Ka Yang, Yani Zhao, Michael A Stashko, Jacqueline L Norris-Drouin, Jarod M Waybright, Serap Beldar, Justin M Rectenwald, Angie L Mordant, Thomas S Webb, Laura E Herring, Cheryl H Arrowsmith, Suzanne Ackloo, Steven P Gygi, Robert K McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I James, Kenneth H Pearce, Stephen V Frye

Journal: Nature Communications

PubMed ID: 39994194

Doi: 10.1038/s41467-025-57005-3

Products & Services: Peptide Synthesis

Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

Authors: Linjiao Zhou, Uriel Ortega-Rodriguez, Matthew J Flores, Yasuyuki Matsumoto, John Q Bettinger, Wells W Wu, Yaqin Zhang, Su-Ryun Kim, Thomas G Biel, Jordan D Pritts, Rong-Fong Shen, V Ashutosh Rao, Tongzhong Ju.

Journal: Nature Communications

PubMed ID: 40000644

Doi: 10.1038/s41467-025-57143-8

Products & Services: Codon Optimization

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation