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Protocol for production and characterization of SARS-CoV-2 PL pro in Escherichia coli

Authors: Anna De Falco; Rebecca Greene-Cramer; Ben A. Shurina; Suren Zakian; Thomas B. Acton; Theresa A. Ramelot; Gaetano T. Montelione

Journal: STAR Protocols

PubMed ID: 40682779

Doi: 10.1016/j.xpro.2025.103952

A D-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of Mycobacterium tuberculosis

Authors: Michael J. Pepi; Shibin Chacko; Gary M. Marqus; Vinayak Singh; Zhe Wang; Kyle Planck; Ryan T. Cullinane; Penchala N. Meka; Deviprasad R. Gollapalli; Thomas R. Ioerger; Kyu Y. Rhee; Gregory D. Cuny; Helena I.M. Boshoff; Lizbeth Hedstrom

Journal: ACS Infectious Diseases

PubMed ID: 35015509

Doi: 10.1021/acsinfecdis.1c00461

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

Products & Services: Recombinant Proteins

ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Protein Electrophoresis and Western

Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

Authors: Shuai Jin, Zixu Zhu, Yunjia Li, Shouyue Zhang, Yijing Liu, Danyuan Li, Yuanqing Li, Yingfeng Luo, Zhiheng Cheng, Kevin Tianmeng Zhao, Qiang Gao, Guanglei Yang, Hongchao Li, Ronghong Liang, Rui Zhang, Jin-Long Qiu, Yong E Zhang, Jun-Jie Gogo Liu, Caixia Gao

Journal: Cell

PubMed ID: 41027434

Doi: doi.org/10.1016/j.cell.2025.09.004

Products & Services: Codon Optimization PCR Cloning and Subcloning

Neutrophil elastase-activatable ratiometric photoacoustic nanoprobes for imaging atherosclerotic plaque vulnerability

Authors: Hui Cao, Xin Meng, Yuan Ma, Zhe Li, Xinyu Xu, Jiaqi Fu, Qingpeng Zhang, Hanlin Wei, Peng Liang, Dingyou Lu, Jinyu Li, Baoli Yin, Shuangyan Huan, Xiao-Bing Zhang, Guosheng Song

Journal: Nature Communications

PubMed ID: 41173886

Doi: 10.1038/s41467-025-64633-2

Products & Services: Catalog Peptides

TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editors

Authors: Min Duan, Pan Gao, Yi-Zhou Zhang, Yu-Long Hu, Lei Zhou, Zhong-Chen Xu, Hou-Yuan Qiu, Xiao-Han Tong, Rui-Jin Ji, Xin-Lin Lei, Hao Yin, Cun-Lan Guo, Ying Zhang

Journal: Nature Chemical Biology

PubMed ID: 40175512

Doi: 10.1038/s41589-025-01867-7

Products & Services: Synthetic Guide RNA

Guidelines in the Preparation of Fully Synthetic, Human Single-Domain Antibody Phage Display Libraries

Authors: Mark A. Tornetta; Brian P. Whitaker; Olivia M. Cantwell; Peter N. Haytko; Eileen D. Pisors; Fulai Zhou; Mark L. Chiu

Journal: Antibodies

PubMed ID: 40843683

Doi: 10.3390/antib14030071

Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance

Authors: Vincent N. Azzolino; Ala M. Shaqra; Akbar Ali; Nese Kurt Yilmaz; Celia A. Schiffer

Journal: Viruses

PubMed ID: 39339895

Doi: 10.3390/v16091419

Products & Services: Peptide Synthesis