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CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation

Authors: Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang

Journal: Sci Adv

PubMed ID: 37205756

Doi: 10.1126/sciadv.adf8698

Products & Services: Molecular Biology Reagents

Analysis and comparisons of gene expression changes in patient- derived neurons from ROHHAD, CCHS, and PWS

Authors: A Kaitlyn Victor, Tayler Hedgecock, Martin Donaldson, Daniel Johnson, Casey M Rand, Debra E Weese-Mayer, Lawrence T Reiter

Journal: Front Pediatr

PubMed ID: 37234859

Doi: 10.3389/fped.2023.1090084

Products & Services: Molecular Biology Reagents

Antibacterial mechanism of the novel antimicrobial peptide Jelleine-Ic and its efficacy in controlling Pseudomonas syringae pv actinidiae in kiwifruit

Authors: Mingyu Zhang, Lifang Wang, Wei Tang, Yue Xing, Pu Liu, Xiangli Dang

Journal: Pest Manag Sci

PubMed ID: 37184207

Doi: 10.1002/ps.7548

Products & Services: Molecular Biology Reagents

Development of new mutant alleles and markers for and via CRISPR/Cas9-mediated mutagenesis to reduce trypsin inhibitor content and activity in soybean seeds

Authors: Zhibo Wang, Zachary Shea, Luciana Rosso, Chao Shang, Jianyong Li, Patrick Bewick, Qi Li, Bingyu Zhao, Bo Zhang

Journal: Front Plant Sci

PubMed ID: 37223818

Doi: 10.3389/fpls.2023.1111680

Products & Services: Protein and Antibody Isolation

Structural analysis of ING3 protein and histone H3 binding

Authors: Mariola Ferreras-Gutiérrez, Belén Chaves-Arquero, Amaia González-Magaña, Nekane Merino, Ignacio Amusategui-Mateu, Sonia Huecas, Francisco J Medrano, Francisco J Blanco

Journal: Int J Biol Macromol

PubMed ID: 37148949

Doi: 10.1016/j.ijbiomac.2023.124724

Products & Services: Protein and Antibody Isolation

A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells

Authors: Peter J Cook, Su Jung Yang, Gene I Uenishi, Annaiz Grimm, Samuel E West, Li-Jie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle P Dahl, Karen Sommer, Andrew M Scharenberg, David J Rawlings

Journal: Mol Ther

PubMed ID: 37147803

Doi: 10.1016/j.ymthe.2023.04.021

Products & Services: Protein and Antibody Isolation

Efficient expression of a cytokine combination in Saccharomyces cerevisiae for cultured meat production

Authors: Qingzi Lei, Jun Ma, Guocheng Du, Jingwen Zhou, Xin Guan

Journal: Food Research International

Doi: 10.1016/j.foodres.2023.113017

Products & Services: Protein and Antibody Isolation

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe

Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim

Journal: Nucleic Acids Research

PubMed ID: 37144518

Doi: 10.1093/nar/gkad363

Products & Services: ORF cDNA Clones/MolecularCloud

Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex

Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček

Journal: Plant J .

PubMed ID: 37191775

Doi: 10.1111/tpj.16282

Products & Services: Gene Synthesis

A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex

Authors: Hong-Wei Zhang, Kun Huang, Zhan-Xi Gu, Xiao-Xian Wu, Jia-Wei Wang, Yu Zhang

Journal: Nat Commun .

PubMed ID: 37253723

Doi: 10.1038/s41467-023-38619-x

Products & Services: Protein and Antibody Isolation