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A mitotic NADPH upsurge promotes chromosome segregation and tumour progression in aneuploid cancer cells

Authors: Aoxing Cheng, Tian Xu , Weiyi You, Ting Wang, Dongming Zhang, Huimin Guo , Haiyan Zhang , Xin Pan , Yucai Wang , Liu Liu , Kaiguang Zhang , Jue Shi , Xuebiao Yao ， Jing Guo , Zhenye Yang

Journal: Nat Metab .

PubMed ID: 37349486

Doi: 10.1038/s42255-023-00832-9

Products & Services: Antibody Modification and Purification Services

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

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Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue

Authors: Colin J. Palmer; Raphael J. Bruckner; Joao A. Paulo; Lawrence Kazak; Jonathan Z. Long; Amir I. Mina; Zhaoming Deng; Katherine B. LeClair; Jessica A. Hall; Shangyu Hong; Peter-James H. Zushin; Kyle L. Smith; Steven P. Gygi; Susan Hagen; David E. Cohen; Alexander S. Banks

Journal: Molecular Metabolism

PubMed ID: 29031721

Doi: 10.1016/j.molmet.2017.07.013

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Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue

Journal: Molecular Metabolism

PubMed ID: 29031721

Doi: 10.1016/j.molmet.2017.07.013

Products & Services: Custom Vector Construction

SAM1 domain of SASH1 harbors distinctive structural heterogeneity

Authors: Christopher M. Clements; Beat V geli; Yiqun G. Shellman; Morkos A. Henen

Journal: Journal of structural biology

PubMed ID: 36341956

Doi: 10.1016/j.jsb.2022.107914

Peptide Inhibitor Assay for Allocating Functionally Important Accessible Sites Throughout a Protein Chain: Restriction Endonuclease EcoRI as a Model Protein System

Authors: Joji M. Otaki

Journal: BioTech

PubMed ID: 39846550

Doi: 10.3390/biotech14010001

Products & Services: Peptide Synthesis

Negatively charged, intrinsically disordered regions can accelerate target search by DNA-binding proteins

Authors: Xi Wang, Lavi S Bigman, Harry M Greenblatt, Binhan Yu, Yaakov Levy, Junji Iwahara

Journal: Nucleic Acids Res

PubMed ID: 36774964

Doi: 10.1093/nar/gkad045

Products & Services: Molecular Biology Reagents

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

Authors: Songnan Wang, Volker Böhnert, Alby J Joseph, Valentino Sudaryo, Jason Swinderman, Feiqiao B Yu, Xuchao Lyu, Gemini Skariah, Vishvak Subramanyam, Luke A Gilbert, Hani Goodarzi, Li Lingyin

Journal: biorxiv

PubMed ID: 37333273

Doi: 10.1101/2023.06.01.543353

Products & Services: Protein and Antibody Isolation

CLDN182 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN182-expressing tumor-directed T-cell activation

Authors: Jing Gao, Zhengyi Wang, Wenqing Jiang, Yanni Zhang, Zhen Meng, Yanling Niu, Zhen Sheng, Chan Chen, Xuejun Liu, Xi Chen, Chanjuan Liu, Keren Jia, Cheng Zhang, Haiyan Liao, Jaeho Jung, Eunsil Sung, Hyejin Chung, Jingwu Z Zhang, Andrew X Zhu, Lin Shen

Journal: J Immunother Cancer

PubMed ID: 37364935

Doi: 10.1136/jitc-2023-006704

Products & Services: Protein and Antibody Isolation

Development and qualification of cell-based relative potency assay for a human respiratory syncytial virus (RSV) mRNA vaccine

Authors: Hualin Helen Li, Jenny Xu, Li He, Lynne Ireland Denny, Richard R Rustandi, Geethanjali Dornadula, Brock Fiorito, Zhi-Qiang Zhang

Journal: J Pharm Biomed Anal

PubMed ID: 37336039

Doi: 10.1016/j.jpba.2023.115523

Products & Services: Protein and Antibody Isolation