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Mouse totipotent blastomere-like cells model embryogenesis from zygotic genome activation to post implantation
Authors: Bing Peng , Qingyi Wang , Feixiang Zhang , Hui Shen , Peng Du
Journal: Cell Stem Cell
PubMed ID: 39826539
Doi: doi.org/10.1016/j.stem.2024.12.006
Single-cycle parainfluenza virus type 5 vectors for producing recombinant proteins, including a humanized anti-V5 tag antibody
Authors: Richard E Randall , Dan Young , Maria Pisliakova , Jelena Andrejeva , Lynsey West , Luis Rossler , Volker Morath , David Hughes , Steve Goodbourn
Journal: JOURNAL OF GENERAL VIROLOGY
PubMed ID: 39786361
Doi: 10.1099/jgv.0.002061
Products & Services: Gene Synthesis   PCR Cloning and Subcloning   
Systematic functional characterization of non-coding regulatory SNPs associated with central obesity
Authors: Shan-Shan Dong, Yuan-Yuan Duan, Ren-Jie Zhu, Ying-Ying Jia, Jia-Xin Chen, Xiao-Ting Huang, Shi-Hao Tang, Ke Yu, Wei Shi, Xiao-Feng Chen, Feng Jiang, Ruo-Han Hao, Yunlong Liu, Zhongbo Liu, Yan Guo, and Tie-Lin Yang
Journal: The American Journal of Human Genetics
Doi: doi.org/10.1016/j.ajhg.2024.11.005
Products & Services: Custom DNA/RNA Oligos   Oligo pool   
Mismatch prime editing gRNA increased efficiency and reduced indels
Authors: Jidong Fei , Dongdong Zhao , Caiyi Pang , Ju Li , Siwei Li , Wentao Qiao , Juan Tan , Changhao Bi , Xueli Zhang
Journal: Nat Commun
PubMed ID: 39747083
Doi: 10.1038/s41467-024-55578-z
Products & Services: Synthetic sgRNA and crRNA Service   
Salivary elicitor disulffde isomerase from Nilaparvata lugens targets host rice UDP-glucose epimerase 2 to induce plant defenses
Authors: Jianmei Fu , Zhichang Zhao , Jichao Fang , Rui Ji
Journal: Plant Stress
Doi: doi.org/10.1016/j.stress.2025.100744
Products & Services: Polyclonal Antibody Services   
Energy-guided accumulated mutation strategy achieves a highly efficient polyethylene terephthalate-degrading enzyme
Authors: Zhi Wang, Jiaxing Zhang, Shengping You, Rongxin Su, Wei Qi
Journal: Biochemical Engineering Journal
Doi: 10.1016/j.bej.2025.109708
Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models
Authors: Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu
Journal: Nature Communications
PubMed ID: 39789054
Products & Services: Synthetic sgRNA and crRNA Service   
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing
Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen
Journal: Int J Biol Macromol
PubMed ID: 39824395
Doi: 10.1016/j.ijbiomac.2025.139953
Products & Services: Gene Synthesis   
Restoring tumor antigenicity activates the “bystander” T cell immune cycle
Authors: Yifan Yang , Qiumin Yu , Haoyu Zhang , Yuchen Liu , Hexuan Wang , Ningyi Yang , Yulian Shi , Wanli Zhang , Zijie Wu , Shitong Huang , Wenbin Xie , Ran Duan , Qiuli Mao , Xupeiyao Shi , Zheng Gao , Xiaoning Wang , Hanlin Guo , Lingxiao Chen , Yi Han , Ximing Li , Liyuan Chen , Siqi Tang , Ying Fan , Wenbing Yao , Hong Tian , Xiangdong Gao
Journal: J Control Release
PubMed ID: 39894265
Doi: 10.1016/j.jconrel.2025.01.094
Products & Services: Gene Synthesis   
Developing orthogonal fluorescent RNAs for photoactive dual-color imaging of RNAs in live cells
Authors: Peng Yin , Chunzheng Huang , Li Zhang , Zhenzhen Li , Caijun Zhong , Shi Kuang , Chunyang Lei , Yan Huang , Zhou Nie
Journal: Angew Chem Int Ed Engl
PubMed ID: 39801450
Doi: 10.1002/anie.202424060
Products & Services: Plasmid DNA Preparation   
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