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A dual regulatory circuit consisting of S -adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei

Authors: Manish M. Patel; Oleg A. Volkov; Christopher Leija; Andrew Lemoff; Margaret A. Phillips

Journal: PLOS Pathogens

PubMed ID: 30365568

Doi: 10.1371/journal.ppat.1007404

Discovery of Fragment-Based Inhibitors of SARS-CoV 2 PL Pro

Authors: Qiangqiang Wei; Ashley J. Taylor; Mahesh Angadrao Barmade; Kevin B. Teuscher; Somanath Chowdhury; Chideraa Apakama; Jordan Anderson-Daniels; Zhu Yongqing; David C. Schultz; Tyson A. Rietz; Taylor M. South; Mackenzie M. Crow; Bin Zhao; Kangsa Amporndanai; John L. Sensintaffar; Jason Phan; Sara Cherry; Mark Denison; Taekyu Lee; Stephen W. Fesik

Journal: Journal of Medicinal Chemistry

PubMed ID: 41521555

Doi: 10.1021/acs.jmedchem.5c02832

Ternary structure of Plasmodium vivax N -myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173

Authors: Cydni Bolling; Alex Mendez; Shane Taylor; Stanley Makumire; Alexandra Reers; Rachael Zigweid; Sandhya Subramanian; David M. Dranow; Bart Staker; Thomas E. Edwards; Edward W. Tate; Andrew S. Bell; Peter J. Myler; Oluwatoyin A. Asojo; Graham Chakafana

Journal: Acta Crystallographica Section F: Structural Biology Communications

PubMed ID: 39291304

Doi: 10.1107/S2053230X24008604

Expression of progerin enhances disease-related endpoints in a tau seeding reporter cell system

Authors: Zhuang Zhuang Han; Sang-Gyun Kang; Erik Gomez-Cardona; Serene Wohlgemuth; Klinton Shmeit; Luis Arce; Jiri G. Safar; Olivier Julien; David Westaway

Journal: Geroscience

PubMed ID: 40660080

Doi: 10.1007/s11357-025-01737-z

Products & Services: Catalog Antibodies

Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

Products & Services: Protein Tools

Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

Products & Services: Bacterial Expression

A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

Products & Services: Gene Synthesis

High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

Products & Services: Gene Synthesis

The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang

Journal: Redox Biol

PubMed ID: 35077997

Doi: 10.1016/j.redox.2022.102244

Products & Services: Peptide Synthesis