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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Authors: Ashleigh Shannon, Véronique Fattorini, Bhawna Sama, Barbara Selisko, Mikael Feracci, Camille Falcou, Pierre Gauffre, Priscila El Kazzi, Adrien Delpal, Etienne Decroly, Karine Alvarez, Cécilia Eydoux, Jean-Claude Guillemot, Adel Moussa, Steven S Good, Paolo La Colla, Kai Lin, Jean-Pierre Sommadossi, Yingxiao Zhu, Xiaodong Yan, Hui Shi, François Ferron, Bruno Canard

Journal: Nat Commun

PubMed ID: 35110538

Doi: 10.1038/s41467-022-28113-1

Products & Services: Custom DNA/RNA Oligos

Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease

Authors: Ádám Diós, Bharani Srinivasan, Judit Gyimesi, Katharina Werkstetter, Rudolf Valenta, Sibylle Koletzko, Ilma R Korponay-Szabó

Journal: Int J Mol Sci

PubMed ID: 35269639

Doi: 10.3390/ijms23052498

Products & Services: Catalog Peptides

Affibody Modified G-quadruplex DNA Micelles Incorporating Polymeric 5-Fluorodeoxyuridine for Targeted Delivery of Curcumin to Enhance Synergetic Therapy of HER2 Positive Gastric Cancer

Authors: Chao Zhang, Shuangqing Fu, Fanghua Zhang, Mengnan Han, Xuming Wang, Jie Du, Honglei Zhang, Wei Li

Journal: Nanomaterials (Basel)

PubMed ID: 35215023

Doi: 10.3390/nano12040696

Products & Services: Custom DNA/RNA Oligos

KIF18B promotes breast cancer cell proliferation, migration and invasion by targeting TRIP13 and activating the Wnt/β-catenin signaling pathway

Authors: Lan Liu, Zhaofeng Zhang, Xiulin Xia, Jing Lei

Journal: Oncol Lett

PubMed ID: 35251343

Doi: 10.3892/ol.2022.13232

Products & Services: Custom Vector Construction

AI-Driven Robotics Laboratory Identifies Pharmacological TNIK Inhibition as a Potent Senomorphic Agent

Authors: Qiuqiong Tang; Deyong Xiao; Alexander Veviorskiy; Ying Xin; Sarah W.Y. Lok; Fadi E. Pulous; Peiran Zhang; Yunfeng Zhu; Yongming Ma; Xiao Hu; Shoulai Gu; Chenting Zong; Sabina Mukba; Mikhail Korzinkin; Frank W. Pun; Man Zhang; Alex Aliper; Lijuan Wu; Feng Ren; Li Zhang; Alex Zhavoronkov

Journal: Aging and Disease

PubMed ID: 39965245

Doi: 10.14336/AD.2024.1492

Products & Services: Recombinant Proteins

AI-Driven Robotics Laboratory Identifies Pharmacological TNIK Inhibition as a Potent Senomorphic Agent

Journal: Aging and Disease

PubMed ID: 39965245

Doi: 10.14336/AD.2024.1492

Products & Services: Recombinant Proteins

Bone-protective effects of deer-hide gelatin in cyclophosphamide-induced osteoporosis rats

Authors: Hongyun Mao; Xinyue Zhao; Shaoqin Mo; Haili Wang; Rui Liu; Yu Xie; Yong Huang; Yunfeng Zheng; Yongqing Hua

Journal: Frontiers in pharmacology

PubMed ID: 41126962

Doi: 10.3389/fphar.2025.1631924

Products & Services: Peptide Synthesis

The receptor CgIL-17R1 expressed in granulocytes mediates the CgIL-17 induced haemocytes proliferation in Crassostrea gigas

Authors: Wanqing Cao, Weilin Wang, Siqi Fan, Jialuo Li, Qing Li, Shasha Wu, Lingling Wang, Linsheng Song

Journal: Dev Comp Immunol

PubMed ID: 35183562

Doi: 10.1016/j.dci.2022.104376

Products & Services: Protein and Antibody Isolation

High level SARS-CoV-2 nucleocapsid refolding using mild condition for inclusion bodies solubilization: Application of high pressure at pH 90

Authors: Rosa Maria Chura-Chambi, Alvaro Rossan de Brandão Prieto-da-Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade Junior, Ligia Morganti

Journal: PLoS ONE

PubMed ID: 35113919

Doi: 10.1371/journal.pone.0262591

Products & Services: Protein and Antibody Isolation

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

Authors: John P Evans, Cong Zeng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu

Journal: Sci Transl Med

PubMed ID: 35166573

Doi: 10.1126/scitranslmed.abn8057

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