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AI-Driven Robotics Laboratory Identifies Pharmacological TNIK Inhibition as a Potent Senomorphic Agent

Authors: Qiuqiong Tang; Deyong Xiao; Alexander Veviorskiy; Ying Xin; Sarah W.Y. Lok; Fadi E. Pulous; Peiran Zhang; Yunfeng Zhu; Yongming Ma; Xiao Hu; Shoulai Gu; Chenting Zong; Sabina Mukba; Mikhail Korzinkin; Frank W. Pun; Man Zhang; Alex Aliper; Lijuan Wu; Feng Ren; Li Zhang; Alex Zhavoronkov

Journal: Aging and Disease

PubMed ID: 39965245

Doi: 10.14336/AD.2024.1492

Products & Services: Recombinant Proteins

Bone-protective effects of deer-hide gelatin in cyclophosphamide-induced osteoporosis rats

Authors: Hongyun Mao; Xinyue Zhao; Shaoqin Mo; Haili Wang; Rui Liu; Yu Xie; Yong Huang; Yunfeng Zheng; Yongqing Hua

Journal: Frontiers in pharmacology

PubMed ID: 41126962

Doi: 10.3389/fphar.2025.1631924

Products & Services: Peptide Synthesis

Blockage of NDUFB9‑SCD1 pathway inhibits adipogenesis

Authors: Shenglong Zhu, Jingwei Zhang, Wei Wang, Xuan Jiang, Yong Q Chen

Journal: J Physiol Biochem

PubMed ID: 35122619

Doi: 10.1007/s13105-022-00876-7

Products & Services: Recombinant Proteins Plasmid DNA Preparation

Characterization of a Group of UDP-Glycosyltransferases Involved in the Biosynthesis of Triterpenoid Saponins of

Authors: Yanting Li, Jianxiu Li, Mengxue Diao, Longyun Peng, Shihai Huang, Nengzhong Xie

Journal: ACS Synth Biol

PubMed ID: 35107265

Doi: 10.1021/acssynbio.1c00469

Products & Services: Gene Synthesis

Germinal centre-driven maturation of B cell response to mRNA vaccination

Authors: Wooseob Kim, Julian Q Zhou, Stephen C Horvath, Aaron J Schmitz, Alexandria J Sturtz, Tingting Lei, Zhuoming Liu, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, Sean P J Whelan, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy

Journal: Nature

PubMed ID: 35168246

Doi: 10.1038/s41586-022-04527-1

Products & Services: Plasmid DNA Preparation

Disentangling the recognition complexity of a protein hub using a nanopore

Authors: Lauren Ashley Mayse, Ali Imran, Motahareh Ghahari Larimi, Michael S Cosgrove, Aaron James Wolfe, Liviu Movileanu

Journal: Nat Commun

PubMed ID: 35190547

Doi: 10.1038/s41467-022-28465-8

Products & Services: Plasmid DNA Preparation

Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy

Authors: Sheng-Han Kuo, Inmaculada Tasset, Melody M Cheng, Antonio Diaz, Ming-Kai Pan, Ori J Lieberman, Samantha J Hutten, Roy N Alcalay, Sangjun Kim, Pilar Ximénez-Embún, Li Fan, Donghoon Kim, Han Seok Ko, Talene Yacoubian, Ellen Kanter, Ling Liu, Guomei Tang, Javier Muñoz, Sergio Pablo Sardi, Aiqun Li, Li Gan, Ana Maria Cuervo, David Sulzer

Journal: Sci Adv

PubMed ID: 35138901

Doi: 10.1126/sciadv.abm6393

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CNOT6: A Novel Regulator of DNA Mismatch Repair

Authors: Peng Song, Shaojun Liu, Dekang Liu, Guido Keijzers, Daniela Bakula, Shunlei Duan, Niels de Wind, Zilu Ye, Sergey Y Vakhrushev, Morten Scheibye-Knudsen, Lene Juel Rasmussen

Journal: Cells

PubMed ID: 35159331

Doi: 10.3390/cells11030521

Products & Services: Plasmid DNA Preparation

mRNA COVID-19 vaccine booster fosters B- and T-cell responses in immunocompromised patients

Authors: Elena Azzolini, Chiara Pozzi, Luca Germagnoli, Bianca Oresta, Nicola Carriglio, Mariella Calleri, Carlo Selmi, Maria De Santis, Silvia Finazzi, Carmelo Carlo-Stella, Alexia Bertuzzi, Francesca Motta, Angela Ceribelli, Alberto Mantovani, Fabrizio Bonelli, Maria Rescigno

Journal: Life Sci Alliance

PubMed ID: 35169017

Doi: 10.26508/lsa.202201381

Humoral Immunity to Allogeneic Immunoproteasome-Expressing Mesenchymal Stromal Cells Requires Efferocytosis by Endogenous Phagocytes

Authors: Jean-Pierre Bikorimana, Jamilah Abusarah, Natasha Salame, Nehme El-Hachem, Riam Shammaa, Moutih Rafei

Journal: Cells

PubMed ID: 35203247

Doi: 10.3390/cells11040596

Products & Services: Peptide Synthesis