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Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6

Authors: Kaito A Nagashima, John V Dzimianski, Meng Yang, Jan Abendroth, Giuseppe A Sautto, Ted M Ross, Rebecca M DuBois, Thomas E Edwards, Jarrod J Mousa

Journal: Structure

PubMed ID: 38810648

Doi: 10.1016/j.str.2024.05.001

Products & Services: Molecular Biology Reagents

Retinoic acid related orphan receptor α is a genetic modifier that rescues retinal degeneration in a mouse model of Stargardt disease and Dry AMD

Authors: M Akula, S M McNamee, Z Love, N Nasraty, N P M Chan, M Whalen, M O Avola, A M Olivares, B D Leehy, A S Jelcick, P Singh, A K Upadhyay, D F Chen, N B Haider

Journal: Gene Ther

PubMed ID: 38755404

Doi: 10.1038/s41434-024-00455-z

Products & Services: Catalog Antibodies

A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Protein and Antibody Isolation

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Authors: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón & Andreas Hougaard Laustsen

Journal: Nat Commun

PubMed ID: 38773068

Doi: 10.1038/s41467-024-48539-z

Products & Services: Gene Synthesis

Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus

Authors: Yuhang Wang, Matthew Theodore, Zhongliang Xing, Utkarsh Narsaria, Zihao Yu, Lanying Zeng, Junjie Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38701202

Doi: 10.1126/sciadv.adl4450

Products & Services: PCR Cloning and Subcloning

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

Products & Services: Protein Electrophoresis and Western

Leptospiral LipL45 lipoprotein undergoes processing and shares structural similarities with bacterial sigma regulators

Authors: Gabriel de Assis Noman, Bárbara Emmanuelle Lacerda de Moura, Mônica Larucci Vieira

Journal: Biochem Biophys Res Commun

PubMed ID: 38718568

Doi: 10.1016/j.bbrc.2024.150057

Products & Services: Protein and Antibody Isolation

Design and Evaluation of a Humanized Anti-EGFR huscFv Antibody Fragment in Combination With Metformin in A549 Cells

Authors: Jorge Solis-Estrada, Eder Arredondo-Espinoza, Elizeth Pioquinto-Ávila, Aldo O González-Cruz, Xristo Zarate, Isaías Balderas-Rentería

Journal: Anticancer Res

PubMed ID: 38677771

Doi: 10.21873/anticanres.16998

Products & Services: Protein and Antibody Isolation

Evaluating the clinical utility of semi-quantitative luciferase immunosorbent assay using antigens in syphilis diagnosis and treatment monitoring

Authors: Wujian Ke, Cailing Ao, Ran Wei, Xiaozhen Zhu, Jingwei Shui, Jianhui Zhao, Xiaohui Zhang, Liuyuan Wang, Liping Huang, Xinying Leng, Rui Zhu, Jiaxin Wu, Lixia Huang, Nanxuan Huang, Haiying Wang, Wenjia Weng, Ligang Yang, Shixing Tang

Journal: Emerg Microbes Infect

PubMed ID: 38661428

Doi: 10.1080/22221751.2024.2348525

Products & Services: Protein and Antibody Isolation

Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones

Authors: Jennifer A Smith, Benjamin T K Yuen, Whitney Purtha, Jared M Balolong, Jonah D Phipps, Frances Crawford, Jeffrey A Bluestone, John W Kappler, Mark S Anderson

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38709934

Doi: 10.1073/pnas.2320268121

Products & Services: Catalog Peptides