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Impaired Humoral Immunity with Concomitant Preserved T Cell Reactivity in IBD Patients on Treatment with Infliximab 6 Month after Vaccination with the SARS-CoV-2 mRNA Vaccine BNT162b2: A Pilot Study

Authors: Richard Vollenberg, Phil-Robin Tepasse, Eva Lorentzen, Tobias Max Nowacki

Journal: J Pers Med

PubMed ID: 35629116

Doi: 10.3390/jpm12050694

BDSF Is a Degradation-Prone Quorum-Sensing Signal Detected by the Histidine Kinase RpfC of pv

Authors: Xiu-Qi Tian, Yao Wu, Zhen Cai, Wei Qian

Journal: Appl Environ Microbiol

PubMed ID: 35369702

Doi: 10.1128/aem.00031-22

Products & Services: Recombinant Proteins

Restoration of Sarco/Endoplasmic Reticulum Ca-ATPase Activity Functions as a Pivotal Therapeutic Target of Anti-Glutamate-Induced Excitotoxicity to Attenuate Endoplasmic Reticulum Ca Depletion

Authors: Wen Zhang, Fanghua Ye, Nan Pang, Miriam Kessi, Juan Xiong, Shimeng Chen, Jing Peng, Li Yang, Fei Yin

Journal: Front Pharmacol

PubMed ID: 35517826

Doi: 10.3389/fphar.2022.877175

Products & Services: Mutagenesis Services

Multiple-Allele MHC Class II Epitope Engineering by a Molecular Dynamics-Based Evolution Protocol

Authors: Rodrigo Ochoa, Victoria Alves Santos Lunardelli, Daniela Santoro Rosa, Alessandro Laio, Pilar Cossio

Journal: Front Immunol

PubMed ID: 35572587

Doi: 10.3389/fimmu.2022.862851

Products & Services: Peptide Synthesis

A conserved module regulates receptor kinase signalling in immunity and development

Authors: Thomas A DeFalco, Pauline Anne, Sean R James, Andrew C Willoughby, Florian Schwanke, Oliver Johanndrees, Yasmine Genolet, Paul Derbyshire, Qian Wang, Surbhi Rana, Anne-Marie Pullen, Frank L H Menke, Cyril Zipfel, Christian S Hardtke, Zachary L Nimchuk

Journal: Nat Plants

PubMed ID: 35422079

Doi: 10.1038/s41477-022-01134-w

Products & Services: Catalog Peptides

Gain-of-function and loss-of-function GABRB3 variants lead to distinct clinical phenotypes in patients with developmental and epileptic encephalopathies

Authors: Nathan L Absalom, Vivian W Y Liao, Katrine M H Johannesen, Elena Gardella, Julia Jacobs, Gaetan Lesca, Zeynep Gokce-Samar, Alexis Arzimanoglou, Shimriet Zeidler, Pasquale Striano, Pierre Meyer, Ira Benkel-Herrenbrueck, Inger-Lise Mero, Jutta Rummel, Mary Chebib, Rikke S Møller, Philip K Ahring

Journal: Nat Commun

PubMed ID: 35383156

Doi: 10.1038/s41467-022-29280-x

Products & Services: PCR Cloning and Subcloning

A Single-Domain TCR-like Antibody Selective for the Qa-1/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint

Authors: Soroush Ghaffari, Katherine Upchurch-Ange, Susanne Gimlin, Trivendra Tripathi, Marjolein Sluijter, Jim Middelburg, Thorbald van Hall, Jon Weidanz

Journal: J Immunol

PubMed ID: 35418467

Doi: 10.4049/jimmunol.2100790

Products & Services: Protein and Antibody Isolation

Structural insight into UV-B-activated UVR8 bound to COP1

Authors: Yidong Wang, Lixia Wang, Zeyuan Guan, Hongfei Chang, Ling Ma, Cuicui Shen, Liang Qiu, Junjie Yan, Delin Zhang, Jian Li, Xing Wang Deng, Ping Yin

Journal: Sci Adv

PubMed ID: 35442727

Doi: 10.1126/sciadv.abn3337

Products & Services: Protein and Antibody Isolation

Humoral immunity against SARS-CoV-2 variants including omicron in solid organ transplant recipients after three doses of a COVID-19 mRNA vaccine

Authors: Kapil K Saharia, Jennifer S Husson, Silke V Niederhaus, Thierry Iraguha, Stephanie V Avila, Youngchae J Yoo, Nancy M Hardy, Xiaoxuan Fan, Destiny Omili, Alice Crane, Amber Carrier, Wen Y Xie, Erica Vander Mause, Kim Hankey, Sherri Bauman, Patricia Lesho, Heather D Mannuel, Ashish Ahuja, Minu Mathew, James Avruch, John Baddley, Olga Goloubeva, Kirti Shetty, Saurabh Dahiya, Aaron P Rapoport, Tim Luetkens, Djordje Atanackovic

Journal: Clin Transl Immunology

PubMed ID: 35505864

Doi: 10.1002/cti2.1391

Products & Services: Catalog Peptides

Tripartite motif containing 63, regulated by E26 transformation specific variant 4, facilitates the thyroid carcinoma progression and the AKT, p38, and ERK signaling pathways

Authors: Jingni He, Ying Zhang, Baiyu Yao, Lidong Wang, Zhong Tian

Journal: Mol Cell Endocrinol

PubMed ID: 35390449

Doi: 10.1016/j.mce.2022.111639

Products & Services: Gene Synthesis