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Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection

Authors: Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao, Guann-Yi Yu

Journal: Front Immunol

PubMed ID: 35585971

Doi: 10.3389/fimmu.2022.872047

Products & Services: Codon Optimization

The E3 ubiquitin ligase RNF216/TRIAD3 is a key coordinator of the hypothalamic-pituitary-gonadal axis

Authors: Arlene J George, Bin Dong, Hannah Lail, Morgan Gomez, Yarely C Hoffiz, Christopher B Ware, Ning Fang, Anne Z Murphy, Erik Hrabovszky, Desiree Wanders, Angela M Mabb

Journal: iScience

PubMed ID: 35620441

Doi: 10.1016/j.isci.2022.104386

Products & Services: Gene Synthesis

PI Kinase-EhGEF2-EhRho5 axis contributes to LPA stimulated macropinocytosis in Entamoeba histolytica

Authors: Achala Apte, Maria Manich, Elisabeth Labruyère, Sunando Datta

Journal: PLoS Pathog

PubMed ID: 35594320

Doi: 10.1371/journal.ppat.1010550

Products & Services: Bacterial Expression

A bivalent vaccine containing D614G and BA.1 spike trimer proteins or a BA.1 spike trimer protein booster shows broad neutralizing immunity

Authors: Peng Du, Ning Li, Xinxin Xiong, Shengjun Tang, Qinjin Dai, Zhihai Liu, Taorui Wang, Xueping Gu, Zhongcheng Zhou

Journal: J Med Virol

PubMed ID: 35614524

Doi: 10.1002/jmv.27885

Products & Services: Gene Synthesis

Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development.

Authors: Blaine Connor, Kayla Titialii-Torres, Abigail E Rockenhaus, Samuel Passamonte, Ann C Morris, Young-Sam Lee

Journal: Sci Rep

PubMed ID: 35508617

Products & Services: Plasmid DNA Preparation

Silk-based hydrogel incorporated with metal-organic framework nanozymes for enhanced osteochondral regeneration

Authors: Zhicheng Cao , Hongmei Wang , Jialin Chen , Yanan Zhang , Qingyun Mo , Po Zhang, Mingyue Wang , Haoyang Liu , Xueyang Bao , Yuzhi Sun , Wei Zhang , Qingqiang Yao

Journal: Bioact Mater

PubMed ID: 35702612

Doi: 10.1016/j.bioactmat.2022.05.025

Products & Services: Protein and Antibody Isolation

Quadrivalent mosaic HexaPro-bearing nanoparticle vaccine protects against infection of SARS-CoV-2 variants

Authors: Yin-Feng Kang , Cong Sun , Jing Sun , Chu Xie , Zhen Zhuang , Hui-Qin Xu , Zheng Liu , Yi-Hao Liu , Sui Peng , Run-Yu Yuan , Jin-Cun Zhao , Mu-Sheng Zeng

Journal: Nat Commun

PubMed ID: 35562337

Doi: 10.1038/s41467-022-30222-w

Products & Services: Gene Synthesis Endotoxin Detection & Removal System

Author Correction: Deletion and tandem duplications of biosynthetic genes drive the diversity of triterpenoids in Aralia elata

Authors: Yu Wang, He Zhang, Hyok Chol Ri, Zeyu An, Xin Wang, Jia-Nan Zhou, Dongran Zheng, Hao Wu, Pengchao Wang, Jianfei Yang, Ding-Kun Liu, Diyang Zhang, Wen-Chieh Tsai, Zheyong Xue, Zhichao Xu, Peng Zhang, Zhong-Jian Liu, Hailong Shen, Yuhua Li

Journal: Nat Commun

PubMed ID: 35523784

Doi: 10.1038/s41467-022-30370-z

Products & Services: Custom Vector Construction

Strong off-target antibody reactivity to malarial antigens induced by RTS,S/AS01E vaccination is associated with protection

Authors: Dídac Macià, Joseph J Campo, Gemma Moncunill, Chenjerai Jairoce, Augusto J Nhabomba, Maximilian Mpina, Hermann Sorgho, David Dosoo, Ousmane Traore, Kwadwo Asamoah Kusi, Nana Aba Williams, Amit Oberai, Arlo Randall, Hèctor Sanz, Clarissa Valim, Kwaku Poku Asante, Seth Owusu-Agyei, Halidou Tinto, Selidji Todagbe Agnandji, Simon Kariuki, Ben Gyan, Claudia Daubenberger, Benjamin Mordmüller, Paula Petrone, Carlota Dobaño

Journal: JCI Insight

PubMed ID: 35446785

Doi: 10.1172/jci.insight.158030

Products & Services: Bacterial Expression

Characterization of Immunological Responses to Immunogenic Protein A (BipA), a Species-Specific Antigen for North American Tick-Borne Relapsing Fever

Authors: Michael W Curtis, Aparna Krishnavajhala, Alexander R Kneubehl, Monica E Embers, Jenna R Gettings, Michael J Yabsley, Job E Lopez

Journal: Microbiol Spectr

PubMed ID: 35579456

Doi: 10.1128/spectrum.01722-21

Products & Services: Plasmid DNA Preparation