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The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

Authors: Robert D Murphy, Tiantian Chen, Jianping Lin, Rongjun He, Li Wu, Caden R Pearson, Savita Sharma, Carl D Vander Kooi, Anthony P Sinai, Zhong-Yin Zhang, Craig W Vander Kooi, Matthew S Gentry

Journal: J Biol Chem

PubMed ID: 35640720

Doi: 10.1016/j.jbc.2022.102089

Products & Services: Mutant Libraries

Sox2 levels regulate the chromatin occupancy of WNT mediators in epiblast progenitors responsible for vertebrate body formation

Authors: Robert Blassberg, Harshil Patel, Thomas Watson, Mina Gouti, Vicki Metzis, M Joaquina Delás, James Briscoe

Journal: Nat Cell Biol

PubMed ID: 35550614

Doi: 10.1038/s41556-022-00910-2

Products & Services: Custom DNA/RNA Oligos

Candidate Chemosensory Genes Identified in the Adult Antennae of and Binding Property of Odorant-Binding Protein 15

Authors: Xiao Li, Jian-Wen Li, Wen-Xiu Sun, Wei Li, Hua-Yuan Gao, Tong-Xian Liu, Ming-Jing Qu

Journal: Front Physiol

PubMed ID: 35711318

Doi: 10.3389/fphys.2022.907667

Products & Services: Protein and Antibody Isolation

Structural variation between neuropeptide isoforms affects function in the lobster cardiac system

Authors: Audrey J Muscato, Daniel J Powell, Warsameh Bulhan, Evalyn S Mackenzie, Alixander Pupo, Madeline Rolph, Andrew E Christie, Patsy S Dickinson

Journal: Gen Comp Endocrinol

PubMed ID: 35623446

Doi: 10.1016/j.ygcen.2022.114065

Products & Services: Peptide Synthesis

Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment

Authors: Yang Liu, Qiang Guo, Heng Yang, Xiao-Wen Zhang, Na Feng, Jing-Kang Wang, Ting-Ting Liu, Ke-Wu Zeng, Peng-Fei Tu

Journal: ACS Cent Sci

PubMed ID: 36032766

Doi: 10.1021/acscentsci.2c00107

Products & Services: Plasmid DNA Preparation

Combinatorial Engineering Enables Photoautotrophic Growth in High Cell Density Phosphite-Buffered Media to Support Engineered Chlamydomonas reinhardtii Bio-Production Concepts

Authors: Malak N Abdallah, Gordon B Wellman, Sebastian Overmans, Kyle J Lauersen

Journal: Frontiers in Microbiology

Doi: 10.3389/fmicb.2022.885840

Products & Services: Plasmid DNA Preparation

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP

Authors: Andrea Pawellek; Ursula Ryder; Triin Tammsalu; Lewis J King; Helmi Kreinin; Tony Ly; Ronald T Hay; Richard C Hartley; Angus I Lamond

Journal: Elife

PubMed ID: 28884683

Doi: 10.7554/eLife.27402

Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug resistant fungi

Authors: Xuefei Chen; H. Diessel Duan; Michael J. Hoy; Kalinka Koteva; Michaela Spitzer; Allison K. Guitor; Emily Puumala; Aline A. Fiebig; Guanggan Hu; Bonnie Yiu; Sommer Chou; Zhuyun Bian; Yeseul Choi; Amelia Bing Ya Guo; Wenliang Wang; Sheng Sun; Nicole Robbins; Anna Floyd Averette; Michael A. Cook; Ray Truant; Lesley T. MacNeil; Eric D. Brown; James W. Kronstad; Brian K. Coombes; Leah E. Cowen; Joseph Heitman; Huilin Li; Gerard D. Wright

Journal: Cell

PubMed ID: 41478284

Doi: 10.1016/j.cell.2025.11.036

Products & Services: Protein and Antibody Isolation

A model for drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly

Authors: Zhaojun Zhong; Tuerxunjiang Maimaiti; Matthew L. Jackson; Rui Dong; Xueyan Gao; Qing Ouyang; Wenqian Wang; Jinliang Guo; Shangrong Li; Wenyu Shang; Huajun Liu; Hongnian Jiang; Shuo Zhang; Ulrich Zachariae; Ben F. Luisi; Yanjie Chao; Dijun Du

Journal: Nature Communications

PubMed ID: 41839863

Doi: 10.1038/s41467-026-70500-5

Products & Services: Protein and Antibody Isolation

Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant

Authors: Kanwal Khan, Salman Ali Khan, Khurshid Jalal, Zaheer Ul-Haq, Reaz Uddin

Journal: Virology

PubMed ID: 35576833

Doi: 10.1016/j.virol.2022.05.001

Products & Services: Peptide Synthesis