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Chemoproteomic identification of CO-dependent lysine carboxylation in proteins

Authors: Dustin T King, Sha Zhu, Darryl B Hardie, Jesús E Serrano-Negrón, Zarina Madden, Subramania Kolappan, David J Vocadlo

Journal: Nat Chem Biol

PubMed ID: 35710617

Doi: 10.1038/s41589-022-01043-1

Products & Services: Mutagenesis Services

Uricase sensitizes hepatocellular carcinoma cells to 5-fluorouracil through uricase-uric acid-UMP synthase axis

Authors: Saihong Yu, Zhuduo Li, Linglan Tu, Yiyi Pu, Dongmei Yan, Xiaoju Wang, Xiaoliang Zheng, Jie Yu

Journal: J Physiol Biochem

PubMed ID: 35674867

Doi: 10.1007/s13105-022-00894-5

Products & Services: Plasmid DNA Preparation

Preclinical evaluation of a plant-derived SARS-CoV-2 subunit vaccine: Protective efficacy, immunogenicity, safety, and toxicity

Authors: Balamurugan Shanmugaraj, Narach Khorattanakulchai, Chalisa Panapitakkul, Ashwini Malla, Rawiwan Im-Erbsin, Manutsanun Inthawong, Piyanate Sunyakumthorn, Taweewun Hunsawong, Chonticha Klungthong, Matthew C Reed, Taratorn Kemthong, Nutchanat Suttisan, Suchinda Malaivijitnond, Passaraporn Srimangkornkaew, Aekkarin Klinkhamhom, Suwimon Manopwisedjaroen, Arunee Thitithanyanont, Suthira Taychakhoonavudh, Waranyoo Phoolcharoen

Journal: Vaccine

PubMed ID: 35697573

Doi: 10.1016/j.vaccine.2022.05.087

Products & Services: Insect Expression

An epitope-optimized human H3N2 influenza vaccine induces broadly protective immunity in mice and ferrets

Authors: Brianna L Bullard, Jennifer DeBeauchamp, Matthew J Pekarek, Erika Petro-Turnquist, Peter Vogel, Richard J Webby, Eric A Weaver

Journal: npj Vaccines

PubMed ID: 35739199

Doi: 10.1038/s41541-022-00492-y

Products & Services: Mammalian Expression

Structural analysis of LpqY, a substrate-binding protein from the SugABC transporter of Mycobacterium tuberculosis, provides insights into its trehalose specificity

Authors: Dipika Sharma, Mandeep Singh, Punit Kaur, Uddipan Das

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35775983

Doi: 10.1107/S2059798322005290

Products & Services: Custom Vector Construction

miR-452-3p Targets HDAC3 to Inhibit p65 Deacetylation and Activate the NF-κB Signaling Pathway in Early Brain Injury after Subarachnoid Hemorrhage

Authors: Junti Lu, Xiaodong Huang, Aiping Deng, Hong Yao, Gao Wu, Na Wang, Hui Gui, Mojie Ren, Shiwen Guo

Journal: Neurocrit Care

PubMed ID: 35641805

Doi: 10.1007/s12028-022-01509-z

Products & Services: Peptide Synthesis

Disease-linked mutations cause exposure of a protein quality control degron

Authors: Caroline Kampmeyer, Sven Larsen-Ledet, Morten Rose Wagnkilde, Mathias Michelsen, Henriette K M Iversen, Sofie V Nielsen, Søren Lindemose, Alberto Caregnato, Tommer Ravid, Amelie Stein, Kaare Teilum, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Structure

PubMed ID: 35700725

Doi: 10.1016/j.str.2022.05.016

Products & Services: Gene Synthesis

Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA

Authors: Elena S Kim, Jun Zhou, Hu Zhang, Alexander Marchetti, Maarten van de Klundert, Dawei Cai, Xiaoyang Yu, Bidisha Mitra, Yuanjie Liu, Mu Wang, Ulrike Protzer, Haitao Guo

Journal: PLoS Pathog

PubMed ID: 35679251

Doi: 10.1371/journal.ppat.1010576

Products & Services: Custom DNA/RNA Oligos

Duplication of horizontally acquired GH5_2 enzymes played a central role in the evolution of longhorned beetles

Authors: Na Ra Shin, Daniel Doucet, Yannick Pauchet

Journal: Mol Biol Evol

PubMed ID: 35763818

Doi: 10.1093/molbev/msac128

Products & Services: Custom Vector Construction

A novel dual-targeting delivery system for specific delivery of CRISPR/Cas9 using hyaluronic acid, chitosan and AS1411

Authors: Zahra Khademi, Mohammad Ramezani, Mona Alibolandi, Mohammad Reza Zirak, Zahra Salmasi, Khalil Abnous, Seyed Mohammad Taghdisi

Journal: Carbohydr Polym

PubMed ID: 35725215

Doi: 10.1016/j.carbpol.2022.119691

Products & Services: Plasmid DNA Preparation