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Effective Functional Immunogenicity of a DNA Vaccine Combination Delivered via In Vivo Electroporation Targeting Malaria Infection and Transmission

Authors: Yi Cao , Clifford T H Hayashi , Fidel Zavala , Abhai K Tripathi , Hayk Simonyan , Colin N Young , Leor C Clark , Yukari Usuda , Jacob M Van Parys , Nirbhay Kumar

Journal: Vaccines (Basel)

PubMed ID: 35891298

Doi: 10.3390/vaccines10071134

Products & Services: Plasmid DNA Preparation

One-pot isothermal LAMP-CRISPR-based assay for Klebsiella pneumoniae detection

Authors: Xiaotong Qiu , Xueping Liu , Xiao Ma , Ruixue Wang , Shenglin Chen , Fang Li , Zhenjun Li

Journal: Microbiol Spectr

PubMed ID: 35856669

Doi: 10.1128/spectrum.01545-22

Products & Services: Synthetic Guide RNA

Direct adenylation from 5?-OH-terminated oligonucleotides by a fusion enzyme containing Pfu RNA ligase and T4 polynucleotide kinase

Authors: Zhengquan Yang , Chengliang Zhang , Guojun Lian , Shijie Dong , Menghui Song , Hengrong Shao , Jingmei Wang , Tao Zhong , Zhenni Luo , Shengnan Jin , Chunming Ding

Journal: Nucleic Acids Res

PubMed ID: 35819229

Doi: org/10.1093/nar/gkac604

Products & Services: Custom DNA/RNA Oligos

Structural insights into the activation of neurokinin 2 receptor by neurokinin A

Authors: Wenjing Sun , Qingning Yuan , Huanhuan Zhang , Fan Yang , Shenglong Ling , Yifan Luo , Pei Lv , H Eric Xu , Changlin Tian , Wanchao Yin , Pan Shi

Journal: Cell Discov

PubMed ID: 35882833

Doi: 10.1038/s41421-022-00437-8

Products & Services: Gene Synthesis

Discrimination between Different DNA Lesions by Monitoring Single-Molecule Polymerase Stalling Kinetics during Nanopore Sequencing

Authors: Jinyue Zhang , Yu Wang , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: Nano Lett

PubMed ID: 35713465

Doi: 10.1021/acs.nanolett.2c01833

Products & Services: Custom DNA/RNA Oligos

Development of a Multi-Epitope Vaccine for and Evaluation of Its Immune Responses in Mice and Piglets

Authors: Gaojian Li, Jinqi Shu, Jing Jin, Jianhong Shu, Huapeng Feng, Jian Chen, Yulong He

Journal: Int J Mol Sci

PubMed ID: 35887246

Doi: 10.3390/ijms23147899

Products & Services: Codon Optimization

Microfluidic Paper-Based Preconcentration and Retrieval for Rapid Ribonucleic Acid Biomarker Detection and Visualization

Authors: Yannan Yu, Fengya Fan, Zachary J Smith, Xi Wei

Journal: Anal Chem

PubMed ID: 35858837

Doi: 10.1021/acs.analchem.2c01442

Products & Services: Molecular Biology Tools

Expression of phenylalanine ammonia lyase as an intracellularly free and extracellularly cell surface-immobilized enzyme on a gut microbe as a live biotherapeutic for phenylketonuria

Authors: Yu Jiang, Bingbing Sun, Fenghui Qian, Feng Dong, Chongmao Xu, Wuling Zhong, Rui Huang, Qiwei Zhai, Yu Jiang, Sheng Yang

Journal: Sci China Life Sci

PubMed ID: 35907113

Doi: 10.1007/s11427-021-2137-3

Products & Services: Gene Synthesis

Biglycan neo-epitope (BGN), a novel biomarker for screening early changes in equine osteoarthritic subchondral bone

Authors: S Adepu, S Ekman, J Leth, U Johansson, A Lindahl, E Skiöldebrand

Journal: Osteoarthritis Cartilage

PubMed ID: 35870736

Doi: 10.1016/j.joca.2022.07.005

Products & Services: Protein and Antibody Isolation

Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model

Authors: Kyle Rosenke, Atsushi Okumura, Matthew C Lewis, Friederike Feldmann, Kimberly Meade-White, W Forrest Bohler, Amanda Griffin, Rebecca Rosenke, Carl Shaia, Michael A Jarvis, Heinz Feldmann

Journal: JCI Insight

PubMed ID: 35579953

Doi: 10.1172/jci.insight.160108

Products & Services: Catalog Antibodies