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Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2

Authors: Jun Lan, Peng Chen, Weiming Liu, Wenlin Ren, Linqi Zhang, Qiang Ding, Qi Zhang, Xinquan Wang, Jiwan Ge

Journal: Structure

PubMed ID: 35917815

Doi: 10.1016/j.str.2022.07.005

Products & Services: Gene Synthesis

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Authors: Brian R Shy, Vivasvan S Vykunta, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye, Jonathan H Esensten, Justin Eyquem, Alexander Marson

Journal: Nat Biotechnol

PubMed ID: 36008610

Doi: 10.1038/s41587-022-01418-8

Products & Services: Gene Synthesis

Novel antiinflammatory biologics shaped by parasite-host coevolution

Authors: Stephanie M Ryan, Roland Ruscher, Wayne A Johnston, Darren A Pickering, Malcolm W Kennedy, Brian O Smith, Linda Jones, Geraldine Buitrago, Matt A Field, Adrian J Esterman, Connor P McHugh, Daniel J Browne, Martha M Cooper, Rachael Y M Ryan, Denise L Doolan, Christian R Engwerda, Kim Miles, Makedonka Mitreva, John Croese, Tony Rahman, Kirill Alexandrov, Paul R Giacomin, Alex Loukas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36037362

Doi: 10.1073/pnas.2202795119

Products & Services: Mammalian Expression

De Novo Design of an Androgen Receptor DNA Binding Domain Targeted peptide PROTAC for Prostate Cancer Therapy

Authors: Bohan Ma; Yizeng Fan; Dize Zhang; Yi Wei; Yanlin Jian; Donghua Liu; Zixi Wang; Yang Gao; Jian Ma; Yule Chen; Shan Xu; Lei Li

Journal: Advanced Science

PubMed ID: 35971165

Doi: 10.1002/advs.202201859

Products & Services: Plasmid DNA Preparation

CRISPR/Cpf1-Mediated Multiplex and Large-Fragment Gene Editing in Staphylococcus aureus

Authors: Zhipeng Wang , Yu Wang , Yujue Wang , Weizhong Chen , Quanjiang Ji

Journal: ACS Synth Biol

PubMed ID: 36001082

Doi: 10.1021/acssynbio.2c00248

Products & Services: Molecular Biology Reagents

Ultrabright nanoparticle-labeled lateral flow immunoassay for detection of anti-SARS-CoV-2 neutralizing antibodies in human serum

Authors: Lun Bian , Zhaoyue Li , An He , Biru Wu , Hui Yang , Yingsong Wu , Fang Hu , Guanfeng Lin , Deqing Zhang

Journal: Biomaterials

PubMed ID: 35977850

Doi: 10.1016/j.biomaterials.2022.121694

Products & Services: Recombinant Proteins

Subtype-Selective Positive Modulation of KCa2.3 Channels Increases Cilia Length

Authors: Young-Woo Nam , Rajasekharreddy Pala , Naglaa Salem El-Sayed , Denisse Larin-Henriquez , Farideh Amirrad , Grace Yang , Mohammad Asikur Rahman , Razan Orfali , Myles Downey , Keykavous Parang , Surya M Nauli , Miao Zhang

Journal: ACS Chem Biol

PubMed ID: 35947779

Doi: 10.1021/acschembio.2c00469

Products & Services: PCR Cloning and Subcloning

Hormone- and antibody-mediated activation of the thyrotropin receptor

Authors: Jia Duan , Peiyu Xu , Xiaodong Luan , Yujie Ji , Xinheng He , Ning Song , Qingning Yuan , Ye Jin , Xi Cheng , Hualiang Jiang , Jie Zheng , Shuyang Zhang , Yi Jiang , H Eric Xu

Journal: Nature

PubMed ID: 35940204

Doi: 10.1038/s41586-022-05173-3

Products & Services: Catalog Peptides Catalog Antibodies

Circular RNA hsa_circ_0007367 promotes the progression of pancreatic ductal adenocarcinoma by sponging miR-6820-3p and upregulating YAP1 expression

Authors: Haocheng Zhang, Xiaolei Ma, Luning Wang, Xinyu Li, Di Feng, Meiming Liu, Jiayang Li, Mengxing Cheng, Na Song, Xinxia Yang, Lina Ba, Yating Lei, Ruipu Zhang, Yunxiao Zhu, Wenxiao Xu, Guofen Qiao

Journal: Cell Death Dis

PubMed ID: 36008392

Doi: 10.1038/s41419-022-05188-8

Products & Services: Protein and Antibody Isolation

Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation

Authors: Maria Pascual-Torner, Dido Carrero, José G Pérez-Silva, Diana Álvarez-Puente, David Roiz-Valle, Gabriel Bretones, David Rodríguez, Daniel Maeso, Elena Mateo-González, Yaiza Español, Guillermo Mariño, José Luis Acuña, Víctor Quesada, Carlos López-Otín

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36037356

Doi: 10.1073/pnas.2118763119

Products & Services: Gene Synthesis