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Mammalian Target of Rapamycin Inhibition Decreases Angiotensin II-Induced Steroidogenesis in HAC15 Human Adrenocortical Carcinoma Cells

Authors: Yusuf Ali, Elise P Gomez-Sanchez, Celso E Gomez-Sanchez

Journal: Endocrinology

PubMed ID: 36320101

Doi: 10.1210/endocr/bqac185

Products & Services: Gene Synthesis

Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43

Authors: Anna Goc, Waldemar Sumera, Matthias Rath, Aleksandra Niedzwiecki

Journal: Sci Rep

PubMed ID: 36352079

Doi: 10.1038/s41598-022-23880-9

Products & Services: DNA Sequencing

New Effective Method of Lactococcus Genome Editing Using Guide RNA-Directed Transposition

Authors: Pavel Yu Pechenov, Danil A Garagulya, Daniil S Stanovov, Andrey V Letarov

Journal: Int J Mol Sci

PubMed ID: 36430465

Doi: 10.3390/ijms232213978

Products & Services: Gene Fragments

Broad-specificity indirect competitive enzyme-linked immunosorbent assay for aristolochic acids: Computer-aided hapten design and molecular mechanism of antibody recognition

Authors: Xiaonan Wang, Qingpeng Lu, Leina Dou, Minggang Liu, Peipei Li, Wenbo Yu, Xuezhi Yu, Zhanhui Wang, Kai Wen

Journal: Sci Total Environ

PubMed ID: 36347294

Doi: 10.1016/j.scitotenv.2022.159941

Products & Services: DNA Sequencing

The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice

Authors: Karianne Fjeld, Anny Gravdal, Ranveig S Brekke, Jahedul Alam, Steven J Wilhelm, Khadija El Jellas, Helene N Pettersen, Jianguo Lin, Marie H Solheim, Solrun J Steine, Bente B Johansson, Pål R Njølstad, Caroline S Verbeke, Xunjun Xiao, Mark E Lowe, Anders Molven

Journal: Pancreatology

PubMed ID: 36379850

Doi: 10.1016/j.pan.2022.11.003

Products & Services: Gene Synthesis

Alginate-Chitosan Hydrogel Formulations Sustain Baculovirus Delivery and VEGFA Expression Which Promotes Angiogenesis for Wound Dressing Applications

Authors: Sabrina Schaly, Paromita Islam, Ahmed Abosalha, Jacqueline L Boyajian, Dominique Shum-Tim, Satya Prakash

Journal: Pharmaceuticals (Basel)

PubMed ID: 36355553

Doi: 10.3390/ph15111382

Products & Services: Plasmid DNA Preparation

Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses

Authors: Ruyu Wang, Guanglei Zhai, Guanghao Zhu, Mengge Wang, Xiaoyi Gong, Weidong Zhang, Guangbo Ge, Hongzhuan Chen, Lili Chen

Journal: Bioorg Chem

PubMed ID: 36395603

Doi: 10.1016/j.bioorg.2022.106264

Products & Services: Gene Synthesis

Structures of trehalose-6-phosphate synthase, Tps1, from the fungal pathogen Cryptococcus neoformans : A target for antifungals

Authors: Erica J. Washington; Ye Zhou; Allen L. Hsu; Matthew Petrovich; Jennifer L. Tenor; Dena L. Toffaletti; Ziqiang Guan; John R. Perfect; Mario J. Borgnia; Alberto Bartesaghi; Richard G. Brennan

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 39083421

Doi: 10.1073/pnas.2314087121

In silico analysis of a novel protein in CAR T- cell therapy for the treatment of hematologic cancer through molecular modelling, docking, and dynamics approach

Authors: Rimjhim Mohanty, Manoswini Manoswini, Ajit Kumar Dhal, Niladri Ganguly

Journal: Comput Biol Med

PubMed ID: 36395593

Doi: 10.1016/j.compbiomed.2022.106285

Products & Services: Custom Vector Construction

synDNA-a Synthetic DNA Spike-in Method for Absolute Quantification of Shotgun Metagenomic Sequencing

Authors: Livia S Zaramela, Megan Tjuanta, Oriane Moyne, Maxwell Neal, Karsten Zengler

Journal: mSystems

PubMed ID: 36317886

Doi: 10.1128/msystems.00447-22

Products & Services: Gene Synthesis