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Sudden death-associated KCNH2 variants exert opposing effects on a nuclear subdomain of the cardiac potassium channel hERG1

Authors: Francisco G Sanchez-Conde, Matthew R Goodrich, Olivia M Stack, Louis N R Goldberg, Pamela K Ruzycki, Abhilasha Jain, Eric N Jimenez-Vazquez, David K Jones

Journal: Molecular Therapy

PubMed ID: 41708004

Doi: 10.1016/j.jbc.2026.111296

Products & Services: Mutagenesis Services

AE-MXene-modified titanium alloy promotes osseointegration by regulating the AMPKMTOR-autophagy pathway in macrophage

Authors: Rui Chao, Lei Sun, Xinyu Xu, Zhan Liu, Xinyi Xu, Zhen Ren, Xinwei Chen, Weifeng Xu, Xuzhuo Chen, Ying Hu, Shanyong Zhang

Journal: Journal of nanobiotechnology

PubMed ID: 41634773

Doi: 10.1186/s12951-026-04080-3

Products & Services: Protein Electrophoresis and Western

Adenine Base Editing Potently Suppresses Hepatitis B Surface Antigen Expression and Inhibits Hepatitis D Virus Release

Authors: Anuj Kumar, Emmanuel Combe, Elena M Smekalova, Selam Dejene, Dominique Leboeuf, Chao-Ying Chen, Léa Mougené, Marine Deleume, Caroline Scholtes, Marie-Laure Plissonnier, Xavier Grand, Maria G Martinez, Giuseppe Ciaramella, Francine Gregoire, Michael S Packer, Barbara Testoni, Fabien Zoulim

Journal: bioRvix

PubMed ID: 41676540

Doi: 10.64898/2026.02.06.704371

Products & Services: PCR Cloning and Subcloning

SmCPK20 phosphorylates SmWRKY2 to regulate jasmonate-mediated tanshinone synthesis in Salvia miltiorrhiza

Authors: Xueying Li, Xiumin Nie, Bolun Li, Xi Han, Xiaona Cai, Qian Yao, Junwen Bu, Jiulin Huang, Bin Zhang, Juane Dong

Journal: Journal of integrative plant biology

PubMed ID: 41736258

Doi: 10.1111/jipb.70195

Products & Services: Catalog Antibodies

MicroRNA-375-3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Authors: Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li

Journal: Advanced Science

PubMed ID: 41674346

Doi: 10.1002/advs.202513486

Products & Services: Catalog Antibodies

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Authors: Lyuba Y Salih, Nicolas L A Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P Moritz, Yannick Tholance, Jean-Philippe Camdessanché, Jean-Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François-Moutal, Aubin Moutal

Journal: Advanced Science

PubMed ID: 41700748

Doi: 10.1002/advs.202511413

Anticodon-edited transfer RNAs (ACE-tRNAs) encoded as therapeutic nonviral minimal DNA vectors

Authors: Joseph J Porter, Wooree Ko, Emily G Sorensen, Zachary Cheung, Kari Thrasher, Tyler Couch, Jeffrey T Gabell, Victoria Shwe, Julia Hyatt, Jennasea B Licata, Luke K Peterson, David A Dean, John D Lueck

Journal: Nucleic Acids Research

PubMed ID: 41641696

Doi: 10.1093/nar/gkag082

A novel two-component system regulates shikimate pathway for thermal adaptation in Thermus thermophilus

Authors: Xuying Bu, Yuwen Guo, Xiangyu Tian, Yuan Shao, Changyou Li, Pan Zhang, Yunxiang Liang, Yingjun Li

Journal: Nucleic Acids Research

PubMed ID: 41693563

Doi: 10.1093/nar/gkag116

Products & Services: Protein and Antibody Isolation

Divergent stem cell mechanisms govern the primary body axis and appendage regeneration in the axolotl

Authors: Liqun Wang, Li Song, Chao Yi, Jing Zhou, Zhouying Yong, Yan Hu, Xiangyu Pan, Na Qiao, Hao Cai, Wandong Zhao, Rui Zhang, Lieke Yang, Lei Liu, Guangdun Peng, Elly M Tanaka, Hanbo Li, Yanmei Liu, Ji-Feng Fei

Journal: SCIENCE ADVANCES

PubMed ID: 41650255

Doi: 10.1126/sciadv.adx5697

Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist

Authors: Eric Gibbs, Bjarne Feddersen, Kayla J Kindig, David Seiferth, Philip C Biggin, Sudha Chakrapani

Journal: SCIENCE ADVANCES

PubMed ID: 41686897

Doi: 10.1126/sciadv.aeb2036