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Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults

Authors: Chanchan Xiao, Zhiyao Ren , Bei Zhang , Lipeng Mao , Guodong Zhu , Lijuan Gao , Jun Su , Jiezhou Ye , Ze Long , Yue Zhu , Pengfei Chen , Xiangmeng Su , Tong Zhou , Yanhao Huang , Xiongfei Chen , Chaojun Xie , Jun Yuan , Yutian Hu , Jingshan Zheng , Zhigang Wang , Jianrong Lou , Xiang Yang , Zhiqiang Kuang , Hongyi Zhang , Pengcheng Wang , Xiaofeng Liang , Oscar Junhong Luo , Guobing Chen

Journal: Nat Aging .

PubMed ID: 37117789

Doi: 10.1038/s43587-023-00379-0

Products & Services: Peptide Synthesis

Diversity of the Gβγ complexes defines spatial and temporal bias of GPCR signaling

Authors: Ikuo Masuho , Nickolas K Skamangas , Brian S Muntean , Kirill A Martemyanov

Journal: Cell Syst .

PubMed ID: 33667409

Doi: 10.1016/j.cels.2021.02.001

Products & Services: Gene Synthesis

Sustained secretion of human growth hormone from TheraCyte devices encapsulated with PiggyBac-engineered retinal pigment epithelium cells

Authors: Claudia R Cecchi, Sidsel Alsing, Gustavo P P Jesus, Enio A Zacarias, Lisbeth Kjaer, Michelle S Clement, Makiko Kumagai-Braesch, Thomas J Corydon, Paolo Bartolini, Cibele N Peroni, Lars Aagaard

Journal: Tissue Cell

PubMed ID: 37087908

Doi: 10.1016/j.tice.2023.102095

Products & Services: Gene Synthesis

l -Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Authors: Remon Soliman; Maria Lorena Cordero-Maldonado; Teresa G. Martins; Mahsa Moein; Jean-Fran ois Conrotte; Rebeccah A. Warmack; Alexander Skupin; Alexander D. Crawford; Steven G. Clarke; Carole L. Linster

Journal: Frontiers in genetics

PubMed ID: 33552132

Doi: 10.3389/fgene.2020.612343

Products & Services: Protein Electrophoresis and Western

l -Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Journal: Frontiers in genetics

PubMed ID: 33552132

Doi: 10.3389/fgene.2020.612343

Products & Services: Protein Electrophoresis and Western

l -Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

Journal: Frontiers in genetics

PubMed ID: 33552132

Doi: 10.3389/fgene.2020.612343

Products & Services: Protein Electrophoresis and Western

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

Authors: Madison S. Strine; Wesley L. Cai; Jin Wei; Mia Madel Alfajaro; Renata B. Filler; Scott B. Biering; Sylvia Sarnik; Ryan D. Chow; Ajinkya Patil; Kasey S. Cervantes; Clayton K. Collings; Peter C. DeWeirdt; Ruth E. Hanna; Kevin Schofield; Christopher Hulme; Silvana Konermann; John G. Doench; Patrick D. Hsu; Cigall Kadoch; Qin Yan; Craig B. Wilen

Journal: PLoS biology

PubMed ID: 37310920

Doi: 10.1371/journal.pbio.3002097

Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

Authors: Akihiro Kitagawa, Tsuyoshi Osawa, Miwa Noda, Yuta Kobayashi, Sho Aki, Yusuke Nakano, Tomoko Saito, Dai Shimizu, Hisateru Komatsu, Maki Sugaya, Junichi Takahashi, Keisuke Kosai, Seiichiro Takao, Yushi Motomura, Kuniaki Sato, Qingjiang Hu, Atsushi Fujii, Hiroaki Wakiyama, Taro Tobo, Hiroki Uchida, Keishi Sugimachi, Kohei Shibata, Tohru Utsunomiya, Shogo Kobayashi, Hideshi Ishii, Takanori Hasegawa, Takaaki Masuda, Yusuke Matsui, Atsushi Niida, Tomoyoshi Soga, Yutaka Suzuki, Satoru Miyano, Hiroyuki Aburatani, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Keiichi I Nakayama, Teppei Shimamura, Tatsuhiro Shibata, Koshi Mimori

Journal: Br J Cancer

PubMed ID: 37076565

Doi: 10.1038/s41416-023-02256-4

Products & Services: Molecular Biology Reagents

Single von Willebrand factor C-domain protein confers host defense against white spot syndrome virus by functioning as a pattern recognition receptor in Macrobrachium nipponense

Authors: Nan Qin, Muyi Li, Han Zhang, Feifei Li, Xinrui Guo, Mengjia Wu, Qingli Zhang, Ting Tang, Fengsong Liu

Journal: Int J Biol Macromol

PubMed ID: 37085073

Doi: 10.1016/j.ijbiomac.2023.124520

Products & Services: Molecular Biology Reagents

19n01, a broadly neutralizing antibody against omicron BA1, BA2, BA4/5, and other SARS-CoV-2 variants of concern

Authors: Melissa García-Vega, Edgar A Melgoza-González, Sofía Hernández-Valenzuela, Diana Hinojosa-Trujillo, Mónica Reséndiz-Sandoval, Mara Anais Llamas-Covarrubias, Martín Loza-López, Olivia Valenzuela, Alan Soto-Gaxiola, Miguel A Hernández-Oñate, Verónica Mata-Haro, Irene Cassaniti, Josè Camilla Sammartino, Alessandro Ferrari, Luca Simonelli, Mattia Pedotti, Rui Sun, Fanglei Zuo, Fausto Baldanti, Luca Varani, Harold Marcotte, Qiang Pan-Hammarström, Jesús Hernández

Journal: iScience

PubMed ID: 37063467

Doi: 10.1016/j.isci.2023.106562

Products & Services: Peptide Synthesis