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Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus

Authors: Mengjun Li, Zuning Ren, Yuelin Wang, Yushan Jiang, Minghui Yang, Delin Li, Jiayin Chen, Zuxin Liang, Yuhao Lin, Zhujun Zeng, Rui Xu, Yiting Wang, Li Zhu, Weiwei Xiao, Qinghua Wu, Bao Zhang, Chengsong Wan, Yang Yang, Bo Wu, Jie Peng, Wei Zhao, Chenguang Shen

Journal: Emerging Microbes & Infections.

PubMed ID: 37288876

Doi: 10.1080/22221751.2023.2223669

Products & Services: Peptide Synthesis

Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis

Authors: Tian Xie , Peng Liu , Xinyue Wu , Feitong Dong, Zike Zhang, Jian Yue, Usha Mahawar, Faheem Farooq, Hisham Vohra, Qi Fang, Wenchen Liu, Binks W Wattenberg, Xin Gong

Journal: Nat Commun.

PubMed ID: 37308477

Doi: 10.1038/s41467-023-39274-y

Products & Services: Protein and Antibody Isolation

Varicella-zoster virus proteome-wide T-cell screening demonstrates low prevalence of virus-specific CD8 T-cells in latently infected human trigeminal ganglia

Authors: Michiel van Gent, Werner J D Ouwendijk, Victoria L Campbell, Kerry J Laing, Georges M G M Verjans, David M Koelle

Journal: J Neuroinflammation

PubMed ID: 37308917

Doi: 10.1186/s12974-023-02820-y

Products & Services: Peptide Synthesis

Improved extracellular vesicle-based mRNA delivery for familial hypercholesterolemia treatment

Authors: Zheng Yang, Panpan Ji, Zhelong Li, Rongxin Zhang, Mengying Wei, Yang Yang, Lijun Yuan, Yan Han, Guodong Yang

Journal: Theranostics

PubMed ID: 37351166

Doi: 10.7150/thno.82873

Products & Services: Recombinant Antibody Expression

Trypanosoma cruzi Tc24 Antigen Expressed and Orally Delivered by Schizochytrium sp Microalga is Immunogenic in Mice

Authors: Abel Ramos-Vega, Elizabeth Monreal-Escalante, Sergio Rosales-Mendoza, Bernardo Bañuelos-Hernández, Eric Dumonteil, Carlos Angulo

Journal: Mol Biotechnol

PubMed ID: 37344711

Doi: 10.1007/s12033-023-00763-6

Products & Services: Peptide Synthesis

Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination

Authors: Hadeel T Zedan, Maria K Smatti, Swapna Thomas, Gheyath K Nasrallah, Nahla M Afifi, Ali Ait Hssain, Laith J Abu Raddad, Peter V Coyle, Jean-Charles Grivel, Muna A Almaslamani, Asmaa A Althani, Hadi M Yassine

Journal: JAMA Netw Open

PubMed ID: 37389876

Doi: 10.1001/jamanetworkopen.2023.19222

Products & Services: ELISA Kits

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

Products & Services: Custom Vector Construction

Engineering B cells with customized therapeutic responses using a synthetic circuit

Authors: Audrey Page, Marie Delles, Didier Nègre, Caroline Costa, Floriane Fusil, François-Loïc Cosset

Journal: Mol Ther Nucleic Acids

PubMed ID: 37359346

Doi: 10.1016/j.omtn.2023.05.024

Products & Services: PCR Cloning and Subcloning

Structural mechanism of intracellular autoregulation of zinc uptake in ZIP transporters

Authors: Changxu Pang, Jin Chai, Ping Zhu, John Shanklin, Qun Liu

Journal: Nat Commun

PubMed ID: 37296139

Doi: 10.1038/s41467-023-39010-6

Products & Services: Gene Synthesis

Scribble mis-localization induces adaptive resistance to KRAS G12C inhibitors through feedback activation of MAPK signaling mediated by YAP-induced MRAS

Authors: Yuta Adachi, Ryo Kimura, Kentaro Hirade, Shogo Yanase, Yuki Nishioka, Natsumi Kasuga, Rui Yamaguchi, Hiromichi Ebi

Journal: Nat Cancer

PubMed ID: 37277529

Doi: 10.1038/s43018-023-00575-2

Products & Services: PCR Cloning and Subcloning